LOCUS       BC008495                1330 bp    mRNA    linear   HUM 15-JUL-2006
DEFINITION  Homo sapiens nucleophosmin (nucleolar phosphoprotein B23,
            numatrin), mRNA (cDNA clone MGC:14826 IMAGE:4276604), complete cds.
ACCESSION   BC008495
VERSION     BC008495.1
KEYWORDS    MGC.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1330)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
   PUBMED   12477932
REFERENCE   2  (bases 1 to 1330)
  CONSRTM   NIH MGC Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-MAY-2001) National Institutes of Health, Mammalian
            Gene Collection (MGC), Bethesda, MD 20892-2590, USA
  REMARK    NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT     Contact: MGC help desk
            Email: cgapbs-r@mail.nih.gov
            Tissue Procurement: ATCC
            cDNA Library Preparation: CLONTECH Laboratories, Inc.
            cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
            DNA Sequencing by: Sequencing Group at the Stanford Human Genome
            Center, Stanford University School of Medicine, Stanford, CA  94305
            Web site:       http://www-shgc.stanford.edu
            Contact:  (Dickson, Mark) mcd@paxil.stanford.edu
            Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
            R. M.
            
            Clone distribution: MGC clone distribution information can be found
            through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
            Series: IRAL Plate: 21 Row: g Column: 20
            This clone was selected for full length sequencing because it
            passed the following selection criteria: matched mRNA gi: 40353733.
FEATURES             Location/Qualifiers
     source          1..1330
                     /db_xref="H-InvDB:HIT000033829"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /clone="MGC:14826 IMAGE:4276604"
                     /tissue_type="Brain, primitive neuroectodermal"
                     /clone_lib="NIH_MGC_56"
                     /lab_host="DH10B"
                     /note="Vector: pDNR-LIB"
     gene            1..1330
                     /gene="NPM1"
                     /gene_synonym="B23"
                     /gene_synonym="NPM"
                     /db_xref="GeneID:4869"
                     /db_xref="HGNC:HGNC:7910"
                     /db_xref="MIM:164040"
     CDS             98..982
                     /gene="NPM1"
                     /gene_synonym="B23"
                     /gene_synonym="NPM"
                     /codon_start=1
                     /product="nucleophosmin (nucleolar phosphoprotein B23,
                     numatrin)"
                     /protein_id="AAH08495.1"
                     /db_xref="GeneID:4869"
                     /db_xref="HGNC:HGNC:7910"
                     /db_xref="MIM:164040"
                     /translation="MEDSMDMDMSPLRPQNYLFGCELKADKDYHFKVDNDENEHQLSL
                     RTVSLGAGAKDELHIVEAEAMNYEGSPIKVTLATLKMSVQPTVSLGGFEITPPVVLRL
                     KCGSGPVHISGQHLVAVEEDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAA
                     DEDDDDDDEEDDDEDDDDDDFDDEEAEEKAPVKKSIRDTPAKNAQKSNQNGKDSKPSS
                     TPRSKGQESFKKQEKTPKTPKGPSSVEDIKAKMQASIEKGGSLPKVEAKFINYVKNCF
                     RMTDQEAIQDLWQWRKSL"
BASE COUNT          452 a          226 c          312 g          340 t
ORIGIN      
        1 tccctggtgt gattccgtcc tgcgcggttg ttctctggag cagcgttctt ttatctccgt
       61 ccgccttctc tcctacctaa gtgcgtgccg ccacccgatg gaagattcga tggacatgga
      121 catgagcccc ctgaggcccc agaactatct tttcggttgt gaactaaagg ccgacaaaga
      181 ttatcacttt aaggtggata atgatgaaaa tgagcaccag ttatctttaa gaacggtcag
      241 tttaggggct ggtgcaaagg atgagttgca cattgttgaa gcagaggcaa tgaattacga
      301 aggcagtcca attaaagtaa cactggcaac tttgaaaatg tctgtacagc caacggtttc
      361 ccttgggggc tttgaaataa caccaccagt ggtcttaagg ttgaagtgtg gttcagggcc
      421 agtgcatatt agtggacagc acttagtagc tgtggaggaa gatgcagagt cagaagatga
      481 agaggaggag gatgtgaaac tcttaagtat atctggaaag cggtctgccc ctggaggtgg
      541 tagcaaggtt ccacagaaaa aagtaaaact tgctgctgat gaagatgatg acgatgatga
      601 tgaagaggat gatgatgaag atgatgatga tgatgatttt gatgatgagg aagctgaaga
      661 aaaagcgcca gtgaagaaat ctatacgaga tactccagcc aaaaatgcac aaaagtcaaa
      721 tcagaatgga aaagactcaa aaccatcatc aacaccaaga tcaaaaggac aagaatcctt
      781 caagaaacag gaaaaaactc ctaaaacacc aaaaggacct agttctgtag aagacattaa
      841 agcaaaaatg caagcaagta tagaaaaagg tggttctctt cccaaagtgg aagccaaatt
      901 catcaattat gtgaagaatt gcttccggat gactgaccaa gaggctattc aagatctctg
      961 gcagtggagg aagtctcttt aagaaaatag tttaaacaat ttgttaaaaa attttccgtc
     1021 ttatttcatt tctgtaacag ttgatatctg gctgtccttt ttataatgca gagtgagaac
     1081 tttccctacc gtgtttgata aatgttgtcc aggttctatt gccaagaatg tgttgtccaa
     1141 aatgcctgtt tagtttttaa agatggaact ccaccctttg cttggtttta agtatgtatg
     1201 gaatgttatg ataggacata gtagtagcgg tggtcagaca tggaaatggt ggggagacaa
     1261 aaatatacat gtgaaataaa actcagtatt ttaataaagc aaaaaaaaaa aaaaaaaaaa
     1321 aaaaaaaaaa
//