LOCUS BC008318 1941 bp mRNA linear HUM 06-MAR-2007
DEFINITION Homo sapiens isoleucyl-tRNA synthetase, mRNA (cDNA clone
IMAGE:3343584), partial cds.
ACCESSION BC008318
VERSION BC008318.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1941)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1941)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (25-MAY-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 22 Row: k Column: 7.
FEATURES Location/Qualifiers
source 1..1941
/db_xref="H-InvDB:HIT000033720"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:3343584"
/tissue_type="Eye, retinoblastoma"
/clone_lib="NIH_MGC_16"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene <1..1941
/gene="IARS"
/gene_synonym="IARS1"
/gene_synonym="ILRS"
/gene_synonym="PRO0785"
/db_xref="GeneID:3376"
/db_xref="HGNC:HGNC:5330"
/db_xref="MIM:600709"
CDS <1..1447
/gene="IARS"
/gene_synonym="IARS1"
/gene_synonym="ILRS"
/gene_synonym="PRO0785"
/codon_start=2
/product="IARS protein"
/protein_id="AAH08318.2"
/db_xref="GeneID:3376"
/db_xref="HGNC:HGNC:5330"
/db_xref="MIM:600709"
/translation="QNLKVLIDPVSVQDKDTLSIHYLMLPRVREELIDKKTESAVSQM
QSVIELGRVIRDRKTIPIKYPLKEIVVIHQDPEALKDIKSLEKYIIEELNVRKVTLST
DKNKYGIRLRAEPDHMVLGKRLKGAFKAVMTSIKQLSSEELEQFQKTGTIVVEGHELH
DEDIRLMYTFDQATGGTAQFEAHSDAQALVLLDVTPDQSMVDEGMAREVINRIQKLRK
KCNLVPTDEITVYYKAKSEGTYLNSVIESHTEFIFTTIKAPLKPYPVSPSDKVLIQEK
TQLKGSELEITLTRGSSLPGPACAYVNLNICANGSEQGGVLLLENPKGDNRLDLLKLK
SVVTSIFGVKNTELAVFHDETEIQNQTDLLSLSGKTLCVTAGSAPSLINSSSTLLCQY
INLQLLNAKPQECLMGTVGTLLLENPLGQNGLTHQGLLYEAAKVFGLRSRKLKLFLNE
TQTQEITEDIPVKTLNMKTVYVSVLPTTADF"
BASE COUNT 627 a 391 c 404 g 519 t
ORIGIN
1 ccagaatcta aaggtgctga ttgaccctgt ttctgttcag gacaaggaca cactcagcat
61 tcactacctc atgctgcccc gtgttcgaga agaattgatt gacaagaaaa cagagagtgc
121 agtatctcag atgcagtctg tgattgaact tggaagagtg atcagagacc gaaaaactat
181 tcccataaag tatcctttga aagaaattgt ggttatccat caagatccag aagctcttaa
241 agatatcaag tctttggaga agtatatcat tgaggaactc aatgttcgaa aagttacact
301 gtctacagat aaaaacaagt atggcattcg gctaagggca gaaccagatc acatggtcct
361 ggggaagcgt ctgaagggag cctttaaggc agtgatgacg tccatcaagc agttgagcag
421 tgaggagctg gagcagttcc agaagactgg gaccattgtt gtggaaggcc atgaattgca
481 cgatgaagac atccgcctca tgtacacctt tgatcaggcc acaggtggga ctgcgcaatt
541 tgaagcacac tcagatgctc aggctttggt cctcttagat gtcactcctg accagtcaat
601 ggtagatgaa ggaatggctc gggaagtcat caatcgcata cagaaacttc gcaaaaagtg
661 caatctggtt ccaactgatg aaatcacagt gtactataaa gcaaagtctg aaggaacata
721 tctgaatagt gttattgaaa gccacacaga gttcatattt accaccataa aggctccctt
781 gaaaccatat ccagtttctc catcggataa agtccttatt caagaaaaaa cacagttgaa
841 gggatctgaa ctggaaatta cactcaccag aggatcttcc cttcctggtc ctgcttgtgc
901 atatgtcaat cttaacattt gtgcaaatgg cagtgaacaa ggtggagtat tgctcctgga
961 aaatccaaaa ggtgacaata ggttggacct tttaaagctg aagagtgttg tcactagcat
1021 ttttggtgtg aaaaatacag agctggctgt cttccatgat gaaacagaaa tacaaaacca
1081 aactgactta ctgagtctta gtggaaaaac actttgtgtg actgcaggat cggctccctc
1141 tctgatcaac agttctagta ctcttctttg tcagtatatc aacctacagc tcctgaatgc
1201 aaagccacaa gagtgtttaa tggggacagt gggcactctc ctgcttgaaa acccacttgg
1261 gcagaatgga ctcacccacc aaggtcttct gtatgaagca gccaaggtgt ttggccttcg
1321 gagcaggaag ctaaagctgt ttctgaatga gacccaaacg caggaaatta cagaagacat
1381 ccccgtgaag actttgaata tgaagactgt gtatgtttct gtgttaccaa caacagcaga
1441 cttctagcat gtacttatca atgttgttcg gtcagccctt ccctaattac acctatcccc
1501 tacacataca tgcacataga cacacacatg aacacactga agatatttcc ttcaggtgtg
1561 tgtaaaatat gctgcttgga ttgaaattca aatgggattg attagtcaag taacttgaga
1621 cctcacagta atcttcacac ttaaccttag acacctatgc agtcatgttg ggagcaggtt
1681 acaatgttac ttcagcccac agtttatttc tatacttgag ttcttaagta cagaagatag
1741 aagtgattta aatggcatag tatatatatc attttctggc cttttaaaat ttatttgaga
1801 cctcttgatg aaatggacat attatatatt tctgccacct ggattttcct ggataatttg
1861 atggaatatt ttaagtttca gtaaatcaga acaataaaca aactcagata taaaaaaaaa
1921 aaaaaaaaaa aaaaaaaaaa a
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