LOCUS BC007878 1749 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens branched chain keto acid dehydrogenase E1, alpha
polypeptide, mRNA (cDNA clone MGC:14115 IMAGE:3938510), complete
cds.
ACCESSION BC007878
VERSION BC007878.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1749)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1749)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (11-MAY-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Dec 9, 2003 this sequence version replaced BC007878.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 20 Row: b Column: 11
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 38372929.
FEATURES Location/Qualifiers
source 1..1749
/db_xref="H-InvDB:HIT000033510"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:14115 IMAGE:3938510"
/tissue_type="Lung, small cell carcinoma"
/clone_lib="NIH_MGC_7"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1749
/gene="BCKDHA"
/gene_synonym="MSU"
/gene_synonym="MSUD1"
/db_xref="GeneID:593"
/db_xref="HGNC:HGNC:986"
/db_xref="MIM:608348"
CDS 6..1343
/gene="BCKDHA"
/gene_synonym="MSU"
/gene_synonym="MSUD1"
/codon_start=1
/product="branched chain keto acid dehydrogenase E1, alpha
polypeptide"
/protein_id="AAH07878.1"
/db_xref="GeneID:593"
/db_xref="HGNC:HGNC:986"
/db_xref="MIM:608348"
/translation="MAVAIAAARVWRLNRGLSQAALLLLRQPGARGLARSHPPRQQQQ
FSSLDDKPQFPGASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKV
LKLYKSMTLLNTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDNTDLVFGQYRE
AGVLMYRDYPLELFMAQCYGNISDLGKGRQMPVHYGCKERHFVTISSPLATQIPQAVG
AAYAAKRANANRVVICYFGEGAASEGDAHAGFNFAATLECPIIFFCRNNGYAISTPTS
EQYRGDGIAARGPGYGIMSIRVDGNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIG
HHSTSDDSSAYRSVDEVNYWDKQDHPISRLRHYLLSQGWWDEEQEKAWRKQSRRKVME
AFEQAERKPKPNPNLLFSDVYQEMPAQLRKQQESLARHLQTYGEHYPLDHFDK"
BASE COUNT 387 a 544 c 504 g 314 t
ORIGIN
1 ccaagatggc ggtagcgatc gctgcagcga gggtctggcg gctaaaccgt ggtttgagcc
61 aggctgccct cctgctgctg cggcagcctg gggctcgggg actggctaga tctcaccccc
121 ccaggcagca gcagcagttt tcatctctgg atgacaagcc ccagttccca ggggcctcgg
181 cggagtttat agataagttg gaattcatcc agcccaacgt catctctgga atccccatct
241 accgcgtcat ggaccggcaa ggccagatca tcaaccccag cgaggacccc cacctgccga
301 aggagaaggt gctgaagctc tacaagagca tgacactgct taacaccatg gaccgcatcc
361 tctatgagtc tcagcggcag ggccggatct ccttctacat gaccaactat ggtgaggagg
421 gcacgcacgt ggggagtgcc gccgccctgg acaacacgga cctggtgttt ggccagtacc
481 gggaggcagg tgtgctgatg tatcgggact accccctgga actattcatg gcccagtgct
541 atggcaacat cagtgacttg ggcaaggggc gccagatgcc tgtccactac ggctgcaagg
601 aacgccactt cgtcactatc tcctctccac tggccacgca gatccctcag gcggtggggg
661 cggcgtacgc agccaagcgg gccaatgcca acagggtcgt catctgttac ttcggcgagg
721 gggcagccag tgagggggac gcccatgccg gcttcaactt cgctgccaca cttgagtgcc
781 ccatcatctt cttctgccgg aacaatggct acgccatctc cacgcccacc tctgagcagt
841 atcgcggcga tggcattgca gcacgaggcc ccgggtatgg catcatgtca atccgcgtgg
901 atggtaatga tgtgtttgcc gtatacaacg ccacaaagga ggcccgacgg cgggctgtgg
961 cagagaacca gccctttctc atcgaggcca tgacctacag gatcgggcac cacagcacca
1021 gtgacgacag ttcagcgtac cgctcggtgg atgaggtcaa ttactgggat aaacaggacc
1081 accccatctc ccggctgcgg cactatctgc tgagccaagg ctggtgggat gaggagcagg
1141 agaaggcctg gaggaagcag tcccgcagga aggtgatgga ggcctttgag caggccgagc
1201 ggaagcccaa acccaacccc aacctgctct tctcagacgt gtatcaggag atgcccgccc
1261 agctccgcaa gcagcaggag tctctggccc gccacctgca gacctacggg gagcactacc
1321 cactggatca cttcgataag tgagacctgc tcagcccacc cccacccatc ctcagctacc
1381 ccgagaggta gccccactct aaggggagca gggggacctg acagcacacc actgtcttcc
1441 ccagtcagct ccctctaaaa tactcagcgg ccagggcggc tgccactctt cacccctgct
1501 cctcccggct gttacattgt caggggacag catctgcagc agttgctgag gctccgtcag
1561 ccccctcttc acctgttgtt acagtgcctt ctcccagggg ctgggtgagg gcacattcag
1621 gactagaagc ccctctgggc atggggtgga catggcaggt cagcctgtgg aacttgcgca
1681 ggtgcgagtg gccagcagag gtcacgaata aactgcatct ctgcgaaaaa aaaaaaaaaa
1741 aaaaaaaaa
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