LOCUS BC007761 1583 bp mRNA linear HUM 11-DEC-2003
DEFINITION Homo sapiens protease, serine, 12 (neurotrypsin, motopsin), mRNA
(cDNA clone MGC:12722 IMAGE:4126901), complete cds.
ACCESSION BC007761
VERSION BC007761.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1583)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1583)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (11-MAY-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Dec 9, 2003 this sequence version replaced BC007761.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 17 Row: h Column: 18
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 21327713.
FEATURES Location/Qualifiers
source 1..1583
/db_xref="H-InvDB:HIT000033428"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:12722 IMAGE:4126901"
/tissue_type="Brain, neuroblastoma"
/clone_lib="NIH_MGC_19"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1583
/gene="PRSS12"
/gene_synonym="BSSP-3"
/gene_synonym="BSSP3"
/gene_synonym="MGC12722"
/gene_synonym="MOTOPSIN"
/db_xref="GeneID:8492"
/db_xref="MIM:606709"
CDS 48..1565
/gene="PRSS12"
/gene_synonym="BSSP-3"
/gene_synonym="BSSP3"
/gene_synonym="MGC12722"
/gene_synonym="MOTOPSIN"
/codon_start=1
/product="PRSS12 protein"
/protein_id="AAH07761.1"
/db_xref="GeneID:8492"
/db_xref="MIM:606709"
/translation="MTLARFVLALMLGALPEVVGFDSVLNDSLHHSHRHSPPAGPHYP
YYLPTQQRPPTTRPPPPLPRFPRPPRALPAQRPHALQAGHTPRPHPWGCPAGEPWVSV
TDFGAPCLRWAEVPPFLERSPPASWAQLRGQRHNFCRSPDGAGRPWCFYGDARGKVDW
GYCDCRHGSVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGI
AKQTPFSGLGLIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPT
FPIIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIAKAWHQAY
FGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTPLTDGVIRLAGG
KGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGKQASANHFEESTGPIWL
DDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIACYPGGEGHRLSLGFPVRLMDG"
misc_feature 342..539
/gene="PRSS12"
/gene_synonym="BSSP-3"
/gene_synonym="BSSP3"
/gene_synonym="MGC12722"
/gene_synonym="MOTOPSIN"
/note="KR; Region: Kringle domain"
/db_xref="CDD:smart00130"
misc_feature 555..857
/gene="PRSS12"
/gene_synonym="BSSP-3"
/gene_synonym="BSSP3"
/gene_synonym="MGC12722"
/gene_synonym="MOTOPSIN"
/note="SR; Region: Scavenger receptor Cys-rich"
/db_xref="CDD:smart00202"
misc_feature 885..1187
/gene="PRSS12"
/gene_synonym="BSSP-3"
/gene_synonym="BSSP3"
/gene_synonym="MGC12722"
/gene_synonym="MOTOPSIN"
/note="SR; Region: Scavenger receptor Cys-rich"
/db_xref="CDD:smart00202"
misc_feature 1206..1505
/gene="PRSS12"
/gene_synonym="BSSP-3"
/gene_synonym="BSSP3"
/gene_synonym="MGC12722"
/gene_synonym="MOTOPSIN"
/note="SR; Region: Scavenger receptor Cys-rich"
/db_xref="CDD:smart00202"
BASE COUNT 343 a 433 c 484 g 323 t
ORIGIN
1 gcccgagaag ctggggagca tggaccagac cccgcagcgc tggcaccatg acgctcgccc
61 gcttcgtgct agccctgatg ttaggggcgc tccccgaagt ggtcggcttt gattctgtcc
121 tcaatgattc cctccaccac agccaccgcc attcgccccc tgcgggtccg cactacccct
181 attaccttcc cacccagcag cggcccccga cgacgcgtcc gccgccgcct ctcccgcgct
241 tcccgcgccc cccgcgggcg ctccctgccc agcgcccgca cgccctccag gccgggcaca
301 cgccccggcc gcacccctgg ggctgccccg ccggcgagcc atgggtcagc gtgacggact
361 tcggcgcccc gtgtctgcgg tgggcggagg tgccaccctt cctggagcgg tcgcccccag
421 cgagctgggc tcagctgcga ggacagcgcc acaacttttg tcggagcccc gacggcgcgg
481 gcagaccctg gtgtttctac ggagacgccc gtggcaaggt ggactggggc tactgcgact
541 gcagacacgg atcagtacga cttcgtggcg gcaaaaatga gtttgaaggc acagtggaag
601 tatatgcaag tggagtttgg ggcactgtct gtagcagcca ctgggatgat tctgatgcat
661 cagtcatttg tcaccagctg cagctgggag gaaaaggaat agcaaaacaa accccgtttt
721 ctggactggg ccttattccc atttattgga gcaatgtccg ttgccgagga gatgaagaaa
781 atatactgct ttgtgaaaaa gacatctggc agggtggggt gtgtcctcag aagatggcag
841 ctgctgtcac gtgtagcttt tcccatggcc caacgttccc catcattcgc cttgctggag
901 gcagcagtgt gcatgaaggc cgggtggagc tctaccatgc tggccagtgg ggaaccgttt
961 gtgatgacca atgggatgat gccgatgcag aagtgatctg caggcagctg ggcctcagtg
1021 gcattgccaa agcatggcat caggcatatt ttggggaagg gtctggccca gttatgttgg
1081 atgaagtacg ctgcactggg aatgagcttt caattgagca gtgtccaaag agctcctggg
1141 gagagcataa ctgtggccat aaagaagatg ctggagtgtc ctgtacccct ctaacagatg
1201 gggtcatcag acttgcaggt gggaaaggca gccatgaggg tcgcttggag gtatattaca
1261 gaggccagtg gggaactgtc tgtgatgatg gctggactga gctgaataca tacgtggttt
1321 gtcgacaatt gggatttaaa tatggtaaac aagcatctgc caaccatttt gaagaaagca
1381 cagggcccat atggttggat gacgtcagct gctcaggaaa ggaaaccaga tttcttcagt
1441 gttccaggcg acagtgggga aggcatgact gcagccaccg cgaagatgtt agcattgcct
1501 gctaccctgg cggcgaggga cacaggctct ctctgggttt tcctgtcaga ctgatggatg
1561 gatgaaaaaa aaaaaaaaaa aaa
//