LOCUS BC007441 1407 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens S-phase kinase-associated protein 2 (p45), mRNA (cDNA
clone MGC:4483 IMAGE:2962938), complete cds.
ACCESSION BC007441
VERSION BC007441.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1407)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1407)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (01-MAY-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 20, 2003 this sequence version replaced BC007441.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 10 Row: d Column: 13
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 16306593.
FEATURES Location/Qualifiers
source 1..1407
/db_xref="H-InvDB:HIT000033225"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:4483 IMAGE:2962938"
/tissue_type="Placenta, choriocarcinoma"
/clone_lib="NIH_MGC_21"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1407
/gene="SKP2"
/gene_synonym="FBL1"
/gene_synonym="FBXL1"
/gene_synonym="FLB1"
/gene_synonym="MGC1366"
/db_xref="GeneID:6502"
/db_xref="HGNC:HGNC:10901"
/db_xref="MIM:601436"
CDS 144..1376
/gene="SKP2"
/gene_synonym="FBL1"
/gene_synonym="FBXL1"
/gene_synonym="FLB1"
/gene_synonym="MGC1366"
/codon_start=1
/product="S-phase kinase-associated protein 2 (p45)"
/protein_id="AAH07441.1"
/db_xref="GeneID:6502"
/db_xref="HGNC:HGNC:10901"
/db_xref="MIM:601436"
/translation="MHRKHLQEIPDLSSNVATSFTWGWDSSKTSELLSGMGVSALEKE
EPDSENIPQELLSNLGHPESPPRKRLKSKGSDKDFVIVRRPKLNRENFPGVSWDSLPD
ELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGV
IAFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEGLRL
SDPIVNTLAKNSNLVRLNLSGCSGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQV
AVAHVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQL
NYLQHLSLSRCYDIIPETLLLVTRAGVRIRLDSDIGCPQTYRTSKLKSSHKLFCQHVR
VICIFVCDFYFYRLVLKQ"
BASE COUNT 360 a 350 c 335 g 362 t
ORIGIN
1 ggaacgttgc taggcttagc gggtctggct gctgggggcc cgagcagcac gctcggagcc
61 gccgcgcgcc aaagcgggaa tctgggaggc gagcagctct gcagttaatg cacgtatttt
121 aaactcccgg gcctgcggac gctatgcaca ggaagcacct ccaggagatt ccagacctga
181 gtagcaacgt tgccaccagc ttcacgtggg gatgggattc cagcaagact tctgaactgc
241 tgtcaggcat gggggtctcc gccctggaga aagaggagcc cgacagtgag aacatccccc
301 aggaactgct ctcaaacctg ggccacccgg agagcccccc acggaaacgg ctgaagagca
361 aagggagtga caaagacttt gtgattgtcc gcaggcctaa gctaaatcga gagaactttc
421 caggtgtttc atgggactcc cttccggatg agctgctctt gggaatcttt tcctgtctgt
481 gcctccctga gctgctaaag gtctctggtg tttgtaagag gtggtatcgc ctagcgtctg
541 atgagtctct atggcagacc ttagacctca caggtaaaaa tctgcacccg gatgtgactg
601 gtcggttgct gtctcaaggg gtgattgcct tccgctgccc acgatcattt atggaccaac
661 cattggctga acatttcagc ccttttcgtg tacagcacat ggacctatcg aactcagtta
721 tagaagtgtc caccctccac ggcatactgt ctcagtgttc caagttgcag aatctaagcc
781 tggaaggcct gcggctttcg gatcccattg tcaatactct cgcaaaaaac tcaaatttag
841 tgcgacttaa cctttctggg tgttctggat tctctgaatt tgccctgcag actttgctaa
901 gcagctgttc cagactggat gagctgaacc tctcctggtg ttttgatttc actgaaaagc
961 atgtacaggt ggctgttgcg catgtgtcag agaccatcac ccagctgaat cttagcggct
1021 acagaaagaa tctccagaaa tcagatctct ctactttagt tagaagatgc cccaatcttg
1081 tccatctaga cttaagtgat agtgtcatgc taaagaatga ctgctttcag gaatttttcc
1141 agctcaacta cctccaacac ctatcactca gtcggtgcta tgatataata cctgaaactt
1201 tactattagt gacaagagct ggggttagga tccggttgga ctctgacatc ggatgccctc
1261 aaacatacag aacttccaaa ctcaagtcca gccataagct attttgccaa catgtcagag
1321 taatctgtat ttttgtatgt gatttctact tttatagact tgttttaaaa caataaaaca
1381 catttttata aaaaaaaaaa aaaaaaa
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