LOCUS BC006089 1339 bp mRNA linear HUM 19-OCT-2006
DEFINITION Homo sapiens phosphomevalonate kinase, mRNA (cDNA clone MGC:12661
IMAGE:3604167), complete cds.
ACCESSION BC006089
VERSION BC006089.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1339)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1339)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (02-APR-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 18 Row: f Column: 9
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 20127505.
FEATURES Location/Qualifiers
source 1..1339
/db_xref="H-InvDB:HIT000032596"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:12661 IMAGE:3604167"
/tissue_type="Uterus, endometrium adenocarcinoma"
/clone_lib="NIH_MGC_44"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1339
/gene="PMVK"
/gene_synonym="HUMPMKI"
/gene_synonym="PMK"
/gene_synonym="PMKA"
/gene_synonym="PMKASE"
/db_xref="GeneID:10654"
/db_xref="HGNC:HGNC:9141"
/db_xref="MIM:607622"
CDS 307..885
/gene="PMVK"
/gene_synonym="HUMPMKI"
/gene_synonym="PMK"
/gene_synonym="PMKA"
/gene_synonym="PMKASE"
/codon_start=1
/product="phosphomevalonate kinase"
/protein_id="AAH06089.1"
/db_xref="GeneID:10654"
/db_xref="HGNC:HGNC:9141"
/db_xref="MIM:607622"
/translation="MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLS
GPLKEQYAQEHGLNFQRLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQP
IWLVSDTRRVSDIQWFREAYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDN
FGDFDWVIENHGVEQRLEEQLENLIEFIRSRL"
BASE COUNT 295 a 328 c 441 g 275 t
ORIGIN
1 gaaggttctg ggcggggctg gactgttcta agtgagttcg ggtgggggag cttcacgagg
61 ggaggctgct ctgtgaagga accgcctttc tctccgcgtg tctcaccctt ttctccccat
121 atctgtttgg acatgagctg agggcacggt cgcgggcggt cagccctgtt cgcagctacg
181 gcgaggaggg gcgcgattgt tccttgttgc cgctccgctt agtggccgcg tccattccgc
241 gcggtgtccc gattttaggg gtagggagaa gtgtcagctt caggcatcgc gaggcgtggc
301 ggccccatgg ccccgctggg aggcgccccg cggctggtac tgctgttcag cggcaagagg
361 aaatccggga aggacttcgt gaccgaggcg ctgcagagca gacttggagc tgatgtctgt
421 gctgtcctcc ggctctctgg tccactcaag gaacagtatg ctcaggagca tggcttgaac
481 ttccagagac tcctggacac cagcacctac aaggaggcct ttcggaagga catgatccgc
541 tggggagagg agaaacgcca ggctgaccca ggcttctttt gcaggaagat tgtggagggc
601 atctcccagc ccatctggct ggtgagtgac acacggagag tgtctgacat ccagtggttt
661 cgggaggcct atggggccgt gacgcagacg gtccgcgttg tagcgttgga gcagagccga
721 cagcagcggg gctgggtgtt cacgccaggg gtggacgatg ctgagtcaga atgtggcctg
781 gacaacttcg gggactttga ctgggtcatc gagaaccatg gagttgaaca gcgcctggag
841 gagcagttgg agaacctgat agaatttatc cgctccagac tttagtcact aggttctagg
901 agtgagctgg ggcctgctga ggtgggggtg gggctgactc tgcaaaatgg gggtgtcccc
961 cgatcctggc cgaggtgagg aacagacagg gggggtctag attctgaggg ggttggtgga
1021 tattgggcaa ggcaggaaac ctctggagac ctcattttct ccatggggaa gacagccatg
1081 ctcttcagga ggagactcca agggcaaagg agggtgtctt ggctgtgctt gaaggcgaaa
1141 ccctgccata tccccagtgc cagtcccctc agcctgtggt ggccttgcat cctgactgga
1201 tgttctcagc cccttgttct gggcaagaac ccagagctcc ccagtgtgga tactaataaa
1261 cctcttggag cacactctca aaacaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
1321 aaaaaaaaaa aacctcggg
//