LOCUS BC005123 2085 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens serine palmitoyltransferase, long chain base subunit
2, mRNA (cDNA clone MGC:10362 IMAGE:3688136), complete cds.
ACCESSION BC005123
VERSION BC005123.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2085)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2085)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (26-MAR-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC005123.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Louis M. Staudt, M.D., Ph.D.
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 14 Row: k Column: 13
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 31881646.
FEATURES Location/Qualifiers
source 1..2085
/db_xref="H-InvDB:HIT000032227"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:10362 IMAGE:3688136"
/tissue_type="Lymph, Burkitt lymphoma"
/clone_lib="NIH_MGC_8"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2085
/gene="SPTLC2"
/gene_synonym="KIAA0526"
/gene_synonym="LCB2"
/gene_synonym="SPT2"
/db_xref="GeneID:9517"
/db_xref="HGNC:HGNC:11278"
/db_xref="MIM:605713"
CDS 90..1778
/gene="SPTLC2"
/gene_synonym="KIAA0526"
/gene_synonym="LCB2"
/gene_synonym="SPT2"
/codon_start=1
/product="serine palmitoyltransferase, long chain base
subunit 2"
/protein_id="AAH05123.1"
/db_xref="GeneID:9517"
/db_xref="HGNC:HGNC:11278"
/db_xref="MIM:605713"
/translation="MRPEPGGCCCRRTVRANGCVANGEVRNGYVRSSAAAAAAAAAGQ
IHHVTQNGGLYKRPFNEAFEETPMLVAVLTYVGYGVLTLFGYLRDFLRYWRIEKCHHA
TEREEQKDFVSLYQDFENFYTRNLYMRIRDNWNRPICSVPGARVDIMERQSHDYNWSF
KYTGNIIKGVINMGSYNYLGFARNTGSCQEAAAKVLEEYGAGVCSTRQEIGNLDKHEE
LEELVARFLGVEAAMAYGMGFATNSMNIPALVGKGCLILSDELNHASLVLGARLSGAT
IRIFKHNNMQSLEKLLKDAIVYGQPRTRRPWKKILILVEGIYSMEGSIVRLPEVIALK
KKYKAYLYLDEAHSIGALGPTGRGVVEYFGLDPEDVDVMMGTFTKSFGASGGYIGGKK
ELIDYLRTHSHSAVYATSLSPPVVEQIITSMKCIMGQDGTSLGKECVQQLAENTRYFR
RRLKEMGFIIYGNEDSPVVPLMLYMPAKIGAFGREMLKRNIGVVVVGFPATPIIESRA
RFCLSAAHTKEILDTALKEIDEVGDLLQLKYSRHRLVPLLDRPFDETTYEETED"
BASE COUNT 591 a 443 c 550 g 501 t
ORIGIN
1 ggtgggtggg gtgcggagcg ggacttggag cagccgccgc cgctgccacc gcctacagag
61 cctgccttgc gcctggtgct gccaggaaga tgcggccgga gcccggaggc tgctgctgcc
121 gccgcacggt gcgggcgaat ggctgcgtgg cgaacgggga agtacggaac gggtacgtga
181 ggagcagcgc tgcagccgca gccgcagccg ccgccggcca gatccatcat gttacacaaa
241 atggaggact atataaaaga ccgtttaatg aagcttttga agaaacacca atgctggttg
301 ctgtgctcac gtatgtgggg tatggcgtac tcaccctctt tggatatctt cgagatttct
361 tgaggtattg gagaattgaa aagtgtcacc atgcaacaga aagagaagaa caaaaggact
421 ttgtgtcatt gtatcaagat tttgaaaact tttatacaag gaatctgtac atgaggataa
481 gagacaactg gaatcggcca atctgtagtg tgcctggagc cagggtggac atcatggaga
541 gacagtctca tgattataac tggtccttca agtatacagg gaatataata aagggtgtta
601 taaacatggg ttcctacaac tatcttggat ttgcacggaa tactggatca tgtcaagaag
661 cagccgccaa agtccttgag gagtatggag ctggagtgtg cagtactcgg caggaaattg
721 gaaacctgga caagcatgaa gaactagagg agcttgtagc aaggttctta ggagtagaag
781 ctgctatggc gtatggcatg ggatttgcaa cgaattcaat gaacattcct gctcttgttg
841 gcaaaggttg cctgattctg agtgatgaac tgaaccatgc atcactggtt ctgggagcca
901 gactgtcagg agcaaccatt agaatcttca aacacaacaa tatgcaaagc ctagagaagc
961 tattgaaaga tgccattgtt tatggtcagc ctcggacacg aaggccctgg aagaaaattc
1021 tcatccttgt ggaaggaata tatagcatgg agggatctat tgttcgtctt cctgaagtga
1081 ttgccctcaa gaagaaatac aaggcatact tgtatctgga tgaggctcac agcattggcg
1141 ccctgggccc cacaggccgg ggtgtggtgg agtactttgg cctggatccc gaggatgtgg
1201 atgttatgat gggaacgttc acaaagagtt ttggtgcttc tggaggatat attggaggca
1261 agaaggagct gatagactac ctgcgaacac attctcatag tgcagtgtat gccacgtcat
1321 tgtcacctcc tgtagtggag cagatcatca cctccatgaa gtgcatcatg gggcaggatg
1381 gcaccagcct tggtaaagag tgtgtacaac agttagctga aaacaccagg tatttcagga
1441 gacgcctgaa agagatgggc ttcatcatct atggaaatga agactctcca gtagtgcctt
1501 tgatgctcta catgcctgcc aaaattggcg cctttggacg ggagatgctg aagcggaaca
1561 tcggtgtcgt tgtggttgga tttcctgcca ccccaattat tgagtccaga gccaggtttt
1621 gcctgtcagc agctcatacc aaagaaatac ttgatactgc tttaaaggag atagatgaag
1681 ttggggacct attgcagctg aagtattccc gtcatcggtt ggtacctcta ctggacaggc
1741 cctttgacga gacgacgtat gaagaaacag aagactgagc ctttttggtg ctccctcaga
1801 ggaactctcc ctcacccagg acagcctgtg gcctttgtga gccagttcca ggaaccacac
1861 ttctgtggcc atctcacgtg aaagacattg cctcagctac tgaaggtggc cacctccact
1921 ctaaatgaca ttttgtaaat agtaaaaaac tgcttctaat ccttcctttg ctaaatctca
1981 cctttaaaaa cgaaggtgac tcactttgct ttttcagtcc attaaaaaaa cattttattt
2041 tgcaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaa
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