LOCUS BC003002 2165 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens polo-like kinase 1 (Drosophila), mRNA (cDNA clone
MGC:3988 IMAGE:2823623), complete cds.
ACCESSION BC003002
VERSION BC003002.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2165)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2165)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (06-FEB-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 9 Row: m Column: 18
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 34147632.
FEATURES Location/Qualifiers
source 1..2165
/db_xref="H-InvDB:HIT000031349"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:3988 IMAGE:2823623"
/tissue_type="Lung, small cell carcinoma"
/clone_lib="NIH_MGC_7"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2165
/gene="PLK1"
/gene_synonym="STPK13"
/db_xref="GeneID:5347"
/db_xref="HGNC:HGNC:9077"
/db_xref="MIM:602098"
CDS 32..1843
/gene="PLK1"
/gene_synonym="STPK13"
/codon_start=1
/product="polo-like kinase 1 (Drosophila)"
/protein_id="AAH03002.1"
/db_xref="GeneID:5347"
/db_xref="HGNC:HGNC:9077"
/db_xref="MIM:602098"
/translation="MSAAVTAGKLARAPADPGKAGVPGVAAPGAPAAAPPAKEIPEVL
VDPRSRRRYVRGRFLGKGGFAKCFEISDADTKEVFAGKIVPKSLLLKPHQREKMSMEI
SIHRSLAHQHVVGFHGFFEDNDFVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQI
VLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYDGERKKTLCGTPNYI
APEVLSKKGHSFEVDVWSIGCIMYTLLVGKPPFETSCLKETYLRIKKNEYSIPKHINP
VAASLIQKMLQTDPTARPTINELLNDEFFTSGYIPARLPITCLTIPPRFSIAPSSLDP
SNRKPLTVLNKGLENPLPERPREKEEPVVRETGEVVDCHLSDMLQQLHSVNASKPSER
GLVRQEEAEDPACIPIFWVSKWVDYSDKYGLGYQLCDNSVGVLFNDSTRLILYNDGDS
LQYIERDGTESYLTVSSHPNSLMKKITLLKYFRNYMSEHLLKAGANITPREGDELARL
PYLRTWFRTRSAIILHLSNGSVQINFFQDHTKLILCPLMAAVTYIDEKRDFRTYRLSL
LEEYGCCKELASRLRYARTMVDKLLSSRSASNRLKAS"
BASE COUNT 484 a 641 c 584 g 456 t
ORIGIN
1 ggatcgaggt ctgcagcgca gcttcgggag catgagtgct gcagtgactg cagggaagct
61 ggcacgggca ccggccgacc ctgggaaagc cggggtcccc ggagttgcag ctcccggagc
121 tccggcggcg gctccaccgg cgaaagagat cccggaggtc ctagtggacc cacgcagccg
181 gcggcgctat gtgcggggcc gctttttggg caagggcggc tttgccaagt gcttcgagat
241 ctcggacgcg gacaccaagg aggtgttcgc gggcaagatt gtgcctaagt ctctgctgct
301 caagccgcac cagagggaga agatgtccat ggaaatatcc attcaccgca gcctcgccca
361 ccagcacgtc gtaggattcc acggcttttt cgaggacaac gacttcgtgt tcgtggtgtt
421 ggagctctgc cgccggaggt ctctcctgga gctgcacaag aggaggaaag ccctgactga
481 gcctgaggcc cgatactacc tacggcaaat tgtgcttggc tgccagtacc tgcaccgaaa
541 ccgagttatt catcgagacc tcaagctggg caaccttttc ctgaatgaag atctggaggt
601 gaaaataggg gattttggac tggcaaccaa agtcgaatat gacggggaga ggaagaagac
661 cctgtgtggg actcctaatt acatagctcc cgaggtgctg agcaagaaag ggcacagttt
721 cgaggtggat gtgtggtcca ttgggtgtat catgtatacc ttgttagtgg gcaaaccacc
781 ttttgagact tcttgcctaa aagagaccta cctccggatc aagaagaatg aatacagtat
841 tcccaagcac atcaaccccg tggccgcctc cctcatccag aagatgcttc agacagatcc
901 cactgcccgc ccaaccatta acgagctgct taatgacgag ttctttactt ctggctatat
961 ccctgcccgt ctccccatca cctgcctgac cattccacca aggttttcga ttgctcccag
1021 cagcctggac cccagcaacc ggaagcccct cacagtcctc aataaaggct tggagaaccc
1081 cctgcctgag cgtccccggg aaaaagaaga accagtggtt cgagagacag gtgaggtggt
1141 cgactgccac ctcagtgaca tgctgcagca gctgcacagt gtcaatgcct ccaagccctc
1201 ggagcgtggg ctggtcaggc aagaggaggc tgaggatcct gcctgcatcc ccatcttctg
1261 ggtcagcaag tgggtggact attcggacaa gtacggcctt gggtatcagc tctgtgataa
1321 cagcgtgggg gtgctcttca atgactcaac acgcctcatc ctctacaatg atggtgacag
1381 cctgcagtac atagagcgtg acggcactga gtcctacctc accgtgagtt cccatcccaa
1441 ctccttgatg aagaagatca ccctccttaa atatttccgc aattacatga gcgagcactt
1501 gctgaaggca ggtgccaaca tcacgccgcg cgaaggtgat gagctcgccc ggctgcccta
1561 cctacggacc tggttccgca cccgcagcgc catcatcctg cacctcagca acggcagcgt
1621 gcagatcaac ttcttccagg atcacaccaa gctcatcttg tgcccactga tggcagccgt
1681 gacctacatc gacgagaagc gggacttccg cacataccgc ctgagtctcc tggaggagta
1741 cggctgctgc aaggagctgg ccagccggct ccgctacgcc cgcactatgg tggacaagct
1801 gctgagctca cgctcggcca gcaaccgtct caaggcctcc taatagctgc cctcccctcc
1861 ggactggtgc cctcctcact cccacctgca tctggggccc atactggttg gctcccgcgg
1921 tgccatgtct gcagtgtgcc ccccagcccc ggtggctggg cagagctgca tcatccttgc
1981 aggtgggggt tgctgtgtaa gttatttttg tacatgttcg ggtgtgggtt ctacagcctt
2041 gtccccctcc ccctcaaccc caccatatga attgtacaga atatttctat tgaattcgga
2101 actgtccttt ccttggcttt atgcacatta aacagatgtg aatattcaaa aaaaaaaaaa
2161 aaaaa
//