LOCUS BC002369 2204 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens polo-like kinase 1 (Drosophila), mRNA (cDNA clone
MGC:8502 IMAGE:2822226), complete cds.
ACCESSION BC002369
VERSION BC002369.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2204)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2204)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (05-FEB-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC002369.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 1 Row: h Column: 13
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 34147632.
FEATURES Location/Qualifiers
source 1..2204
/db_xref="H-InvDB:HIT000030836"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:8502 IMAGE:2822226"
/tissue_type="Lung, small cell carcinoma"
/clone_lib="NIH_MGC_7"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2204
/gene="PLK1"
/gene_synonym="STPK13"
/db_xref="GeneID:5347"
/db_xref="HGNC:HGNC:9077"
/db_xref="MIM:602098"
CDS 54..1865
/gene="PLK1"
/gene_synonym="STPK13"
/codon_start=1
/product="polo-like kinase 1 (Drosophila)"
/protein_id="AAH02369.1"
/db_xref="GeneID:5347"
/db_xref="HGNC:HGNC:9077"
/db_xref="MIM:602098"
/translation="MSAAVTAGKLARAPADPGKAGVPGVAAPGAPAAAPPAKEIPEVL
VDPRSRRRYVRGRFLGKGGFAKCFEISDADTKEVFAGKIVPKSLLLKPHQREKMSMEI
SIHRSLAHQHVVGFHGFFEDNDFVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQI
VLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYDGERKKTLCGTPNYI
APEVLSKKGHSFEVDVWSIGCIMYTLLVGKPPFETSCLKETYLRIKKNEYSIPKHINP
VAASLIQKMLQTDPTARPTINELLNDEFFTSGYIPARLPITCLTIPPRFSIAPSSLDP
SNRKPLTVLNKGLENPLPERPREKEEPVVRETGEVVDCHLSDMLQQLHSVNASKPSER
GLVRQEEAEDPACIPIFWVSKWVDYSDKYGLGYQLCDNSVGVLFNDSTRLILYNDGDS
LQYIERDGTESYLTVSSHPNSLMKKITLLKYFRNYMSEHLLKAGANITPREGDELARL
PYLRTWFRTRSAIILHLSNGSVQINFFQDHTKLILCPLMAAVTYIDEKRDFRTYRLSL
LEEYGCCKELASRLRYARTMVDKLLSSRSASNRLKAS"
BASE COUNT 503 a 647 c 594 g 460 t
ORIGIN
1 gagcggtgcg gaggctctgc tcggatcgag gtctgcagcg cagcttcggg agcatgagtg
61 ctgcagtgac tgcagggaag ctggcacggg caccggccga ccctgggaaa gccggggtcc
121 ccggagttgc agctcccgga gctccggcgg cggctccacc ggcgaaagag atcccggagg
181 tcctagtgga cccacgcagc cggcggcgct atgtgcgggg ccgctttttg ggcaagggcg
241 gctttgccaa gtgcttcgag atctcggacg cggacaccaa ggaggtgttc gcgggcaaga
301 ttgtgcctaa gtctctgctg ctcaagccgc accagaggga gaagatgtcc atggaaatat
361 ccattcaccg cagcctcgcc caccagcacg tcgtaggatt ccacggcttt ttcgaggaca
421 acgacttcgt gttcgtggtg ttggagctct gccgccggag gtctctcctg gagctgcaca
481 agaggaggaa agccctgact gagcctgagg cccgatacta cctacggcaa attgtgcttg
541 gctgccagta cctgcaccga aaccgagtta ttcatcgaga cctcaagctg ggcaaccttt
601 tcctgaatga agatctggag gtgaaaatag gggattttgg actggcaacc aaagtcgaat
661 atgacgggga gaggaagaag accctgtgtg ggactcctaa ttacatagct cccgaggtgc
721 tgagcaagaa agggcacagt ttcgaggtgg atgtgtggtc cattgggtgt atcatgtata
781 ccttgttagt gggcaaacca ccttttgaga cttcttgcct aaaagagacc tacctccgga
841 tcaagaagaa tgaatacagt attcccaagc acatcaaccc cgtggccgcc tccctcatcc
901 agaagatgct tcagacagat cccactgccc gcccaaccat taacgagctg cttaatgacg
961 agttctttac ttctggctat atccctgccc gtctccccat cacctgcctg accattccac
1021 caaggttttc gattgctccc agcagcctgg accccagcaa ccggaagccc ctcacagtcc
1081 tcaataaagg cttggagaac cccctgcctg agcgtccccg ggaaaaagaa gaaccagtgg
1141 ttcgagagac aggtgaggtg gtcgactgcc acctcagtga catgctgcag cagctgcaca
1201 gtgtcaatgc ctccaagccc tcggagcgtg ggctggtcag gcaagaggag gctgaggatc
1261 ctgcctgcat ccccatcttc tgggtcagca agtgggtgga ctattcggac aagtacggcc
1321 ttgggtatca gctctgtgat aacagcgtgg gggtgctctt caatgactca acacgcctca
1381 tcctctacaa tgatggtgac agcctgcagt acatagagcg tgacggcact gagtcctacc
1441 tcaccgtgag ttcccatccc aactccttga tgaagaagat caccctcctt aaatatttcc
1501 gcaattacat gagcgagcac ttgctgaagg caggtgccaa catcacgccg cgcgaaggtg
1561 atgagctcgc ccggctgccc tacctacgga cctggttccg cacccgcagc gccatcatcc
1621 tgcacctcag caacggcagc gtgcagatca acttcttcca ggatcacacc aagctcatct
1681 tgtgcccact gatggcagcc gtgacctaca tcgacgagaa gcgggacttc cgcacatacc
1741 gcctgagtct cctggaggag tacggctgct gcaaggagct ggccagccgg ctccgctacg
1801 cccgcactat ggtggacaag ctgctgagct cacgctcggc cagcaaccgt ctcaaggcct
1861 cctaatagct gccctcccct ccggactggt gccctcctca ctcccacctg catctggggc
1921 ccatactggt tggctcccgc ggtgccatgt ctgcagtgtg ccccccagcc ccggtggctg
1981 ggcagagctg catcatcctt gcaggtgggg gttgctgtgt aagttatttt tgtacatgtt
2041 cgggtgtggg ttctacagcc ttgtccccct ccccctcaac cccaccatat gaattgtaca
2101 gaatatttct attgaattcg gaactgtcct ttccttggct ttatgcacat taaacagatg
2161 tgaatattca aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaa
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