LOCUS BC001479 1240 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens aldo-keto reductase family 1, member C3 (3-alpha
hydroxysteroid dehydrogenase, type II), mRNA (cDNA clone MGC:1160
IMAGE:2988160), complete cds.
ACCESSION BC001479
VERSION BC001479.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1240)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1240)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (21-DEC-2000) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 20, 2003 this sequence version replaced BC001479.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 3 Row: d Column: 7
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 24497582.
FEATURES Location/Qualifiers
source 1..1240
/db_xref="H-InvDB:HIT000030442"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:1160 IMAGE:2988160"
/tissue_type="Colon, adenocarcinoma"
/clone_lib="NIH_MGC_15"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1240
/gene="AKR1C3"
/gene_synonym="DD3"
/gene_synonym="HA1753"
/gene_synonym="HAKRB"
/gene_synonym="HAKRe"
/gene_synonym="hluPGFS"
/gene_synonym="KIAA0119"
/db_xref="GeneID:8644"
/db_xref="HGNC:HGNC:386"
/db_xref="MIM:603966"
CDS 57..1028
/gene="AKR1C3"
/gene_synonym="DD3"
/gene_synonym="HA1753"
/gene_synonym="HAKRB"
/gene_synonym="HAKRe"
/gene_synonym="hluPGFS"
/gene_synonym="KIAA0119"
/codon_start=1
/product="aldo-keto reductase family 1, member C3 (3-alpha
hydroxysteroid dehydrogenase, type II)"
/protein_id="AAH01479.1"
/db_xref="GeneID:8644"
/db_xref="HGNC:HGNC:386"
/db_xref="MIM:603966"
/translation="MDSKHQCVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEA
GFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENS
LKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLA
KSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSA
LGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQR
IRQNVQVFEFQLTAEDMKAIDGLDRNLHYFNSDSFASHPNYPYSDEY"
BASE COUNT 381 a 269 c 288 g 302 t
ORIGIN
1 gtaatctctg aggagaagca gcagcaaaca tttgctagtc agacaagtga cagggaatgg
61 attccaaaca ccagtgtgta aagctaaatg atggccactt catgcctgta ttgggatttg
121 gcacctatgc acctccagag gttccaagaa gtaaagcttt ggaggtcaca aaattagcaa
181 tagaagctgg gttccgccat atagattctg ctcatttata caataatgag gagcaggttg
241 gactggccat ccgaagcaag attgcagatg gcagtgtgaa gagagaagac atattctaca
301 cttcaaagct ttggtccact tttcatcgac cagagttggt ccgaccagcc ttggaaaact
361 cactgaaaaa agctcaattg gactatgttg acctctatct tattcattct ccaatgtctc
421 taaagccagg tgaggaactt tcaccaacag atgaaaatgg aaaagtaata tttgacatag
481 tggatctctg taccacctgg gaggccatgg agaagtgtaa ggatgcagga ttggccaagt
541 ccattggggt gtcaaacttc aaccgcaggc agctggagat gatcctcaac aagccaggac
601 ttaagtacaa gcctgtctgc aaccaggtag aatgtcatcc gtatttcaac cggagtaaat
661 tgctagattt ctgcaagtcg aaagatattg ttctggttgc ctatagtgct ctgggatctc
721 aacgagacaa acgatgggtg gacccgaact ccccggtgct cttggaggac ccagtccttt
781 gtgccttggc aaaaaagcac aagcgaaccc cagccctgat tgccctgcgc taccagctgc
841 agcgtggggt tgtggtcctg gccaagagct acaatgagca gcgcatcaga cagaacgtgc
901 aggtttttga gttccagttg actgcagagg acatgaaagc catagatggc ctagacagaa
961 atctccacta ttttaacagt gatagttttg ctagccaccc taattatcca tattcagatg
1021 aatattaaca tggagagctt tgcctgatgt ctaccagaag ccctgtgtgt ggatggtgac
1081 gcagaggacg tctctatgcc ggtgactgga catatcacct ctacttaaat ccgtcctgtt
1141 tagcgacttc agtcaactac agctgagtcc atagcccaga aagacaataa atttttatca
1201 ttttgaaata aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
//