LOCUS BC001441 1425 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens S-phase kinase-associated protein 2 (p45), mRNA (cDNA
clone MGC:1366 IMAGE:3138709), complete cds.
ACCESSION BC001441
VERSION BC001441.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1425)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1425)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (12-DEC-2000) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC001441.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 4 Row: d Column: 17
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 16306593.
FEATURES Location/Qualifiers
source 1..1425
/db_xref="H-InvDB:HIT000030417"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:1366 IMAGE:3138709"
/tissue_type="Placenta, choriocarcinoma"
/clone_lib="NIH_MGC_21"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1425
/gene="SKP2"
/gene_synonym="FBL1"
/gene_synonym="FBXL1"
/gene_synonym="FLB1"
/gene_synonym="MGC1366"
/db_xref="GeneID:6502"
/db_xref="HGNC:HGNC:10901"
/db_xref="MIM:601436"
CDS 140..1372
/gene="SKP2"
/gene_synonym="FBL1"
/gene_synonym="FBXL1"
/gene_synonym="FLB1"
/gene_synonym="MGC1366"
/codon_start=1
/product="S-phase kinase-associated protein 2 (p45)"
/protein_id="AAH01441.1"
/db_xref="GeneID:6502"
/db_xref="HGNC:HGNC:10901"
/db_xref="MIM:601436"
/translation="MHRKHLQEIPDLSSNVATSFTWGWDSSKTSELLSGMGVSALEKE
EPDSENIPQELLSNLGHPESPPRKRLKSKGSDKDFVIVRRPKLNRENFPGVSWDSLPD
ELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGV
IAFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEGLRL
SDPIVNTLAKNSNLVRLNLSGCSGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQV
AVAHVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQL
NYLQHLSLSRCYDIIPETLLLVTRAGVRIRLDSDIGCPQTYRTSKLKSSHKLFCQHVR
VICIFVCDFYFYRLVLKQ"
BASE COUNT 371 a 352 c 336 g 366 t
ORIGIN
1 cgttgctagg cttagcgggt ctggctgctg ggggcccgag cagcacgctc ggagccgccg
61 cgcgccaaag cgggaatctg ggaggcgagc agctctgcag ttaatgcacg tattttaaac
121 tcccgggcct gcggacgcta tgcacaggaa gcacctccag gagattccag acctgagtag
181 caacgttgcc accagcttca cgtggggatg ggattccagc aagacttctg aactgctgtc
241 aggcatgggg gtctccgccc tggagaaaga ggagcccgac agtgagaaca tcccccagga
301 actgctctca aacctgggcc acccggagag ccccccacgg aaacggctga agagcaaagg
361 gagtgacaaa gactttgtga ttgtccgcag gcctaagcta aatcgagaga actttccagg
421 tgtttcatgg gactcccttc cggatgagct gctcttggga atcttttcct gtctgtgcct
481 ccctgagctg ctaaaggtct ctggtgtttg taagaggtgg tatcgcctag cgtctgatga
541 gtctctatgg cagaccttag acctcacagg taaaaatctg cacccggatg tgactggtcg
601 gttgctgtct caaggggtga ttgccttccg ctgcccacga tcatttatgg accaaccatt
661 ggctgaacat ttcagccctt ttcgtgtaca gcacatggac ctatcgaact cagttataga
721 agtgtccacc ctccacggca tactgtctca gtgttccaag ttgcagaatc taagcctgga
781 aggcctgcgg ctttcggatc ccattgtcaa tactctcgca aaaaactcaa atttagtgcg
841 acttaacctt tctgggtgtt ctggattctc tgaatttgcc ctgcagactt tgctaagcag
901 ctgttccaga ctggatgagc tgaacctctc ctggtgtttt gatttcactg aaaagcatgt
961 acaggtggct gttgcgcatg tgtcagagac catcacccag ctgaatctta gcggctacag
1021 aaagaatctc cagaaatcag atctctctac tttagttaga agatgcccca atcttgtcca
1081 tctagactta agtgatagtg tcatgctaaa gaatgactgc tttcaggaat ttttccagct
1141 caactacctc caacacctat cactcagtcg gtgctatgat ataatacctg aaactttact
1201 attagtgaca agagctgggg ttaggatccg gttggactct gacatcggat gccctcaaac
1261 atacagaact tccaaactca agtccagcca taagctattt tgccaacatg tcagagtaat
1321 ctgtattttt gtatgtgatt tctactttta tagacttgtt ttaaaacaat aaaacacatt
1381 tttataaaaa tgagtgctta aaaacaaaaa aaaaaaaaaa aaaaa
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