LOCUS BC000301 2084 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens histone deacetylase 1, mRNA (cDNA clone MGC:8378
IMAGE:2820260), complete cds.
ACCESSION BC000301
VERSION BC000301.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2084)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2084)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (15-NOV-2000) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Nov 6, 2003 this sequence version replaced BC000301.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 1 Row: c Column: 9
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 13128859.
FEATURES Location/Qualifiers
source 1..2084
/db_xref="H-InvDB:HIT000029498"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:8378 IMAGE:2820260"
/tissue_type="Lung, small cell carcinoma"
/clone_lib="NIH_MGC_7"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2084
/gene="HDAC1"
/gene_synonym="GON-10"
/gene_synonym="HD1"
/gene_synonym="RPD3"
/db_xref="GeneID:3065"
/db_xref="HGNC:HGNC:4852"
/db_xref="MIM:601241"
CDS 35..1483
/gene="HDAC1"
/gene_synonym="GON-10"
/gene_synonym="HD1"
/gene_synonym="RPD3"
/codon_start=1
/product="histone deacetylase 1"
/protein_id="AAH00301.1"
/db_xref="GeneID:3065"
/db_xref="HGNC:HGNC:4852"
/db_xref="MIM:601241"
/translation="MAQTQGTRRKVCYYYDGDVGNYYYGQGHPMKPHRIRMTHNLLLN
YGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPV
FDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAI
LELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGK
GKYYAVNYPLRDGIDDESYEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNL
TIKGHAKCVEFVKSFNLPMLMLGGGGYTIRNVARCWTYETAVALDTEIPNELPYNDYF
EYFGPDFKLHISPSNMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAIPEDAIPEE
SGDEDEDDPDKRISICSSDKRIACEEEFSDSEEEGEGGRKNSSNFKKAKRVKTEDEKE
KDPEEKKEVTEEEKTKEEKPEAKGVKEEVKLA"
BASE COUNT 568 a 478 c 526 g 512 t
ORIGIN
1 gaccgactga cggtagggac gggaggcgag caagatggcg cagacgcagg gcacccggag
61 gaaagtctgt tactactacg acggggatgt tggaaattac tattatggac aaggccaccc
121 aatgaagcct caccgaatcc gcatgactca taatttgctg ctcaactatg gtctctaccg
181 aaaaatggaa atctatcgcc ctcacaaagc caatgctgag gagatgacca agtaccacag
241 cgatgactac attaaattct tgcgctccat ccgtccagat aacatgtcgg agtacagcaa
301 gcagatgcag agattcaacg ttggtgagga ctgtccagta ttcgatggcc tgtttgagtt
361 ctgtcagttg tctactggtg gttctgtggc aagtgctgtg aaacttaata agcagcagac
421 ggacatcgct gtgaattggg ctgggggcct gcaccatgca aagaagtccg aggcatctgg
481 cttctgttac gtcaatgata tcgtcttggc catcctggaa ctgctaaagt atcaccagag
541 ggtgctgtac attgacattg atattcacca tggtgacggc gtggaagagg ccttctacac
601 cacggaccgg gtcatgactg tgtcctttca taagtatgga gagtacttcc caggaactgg
661 ggacctacgg gatatcgggg ctggcaaagg caagtattat gctgttaact acccgctccg
721 agacgggatt gatgacgagt cctatgaggc cattttcaag ccggtcatgt ccaaagtaat
781 ggagatgttc cagcctagtg cggtggtctt acagtgtggc tcagactccc tatctgggga
841 tcggttaggt tgcttcaatc taactatcaa aggacacgcc aagtgtgtgg aatttgtcaa
901 gagctttaac ctgcctatgc tgatgctggg aggcggtggt tacaccattc gtaacgttgc
961 ccggtgctgg acatatgaga cagctgtggc cctggatacg gagatcccta atgagcttcc
1021 atacaatgac tactttgaat actttggacc agatttcaag ctccacatca gtccttccaa
1081 tatgactaac cagaacacga atgagtacct ggagaagatc aaacagcgac tgtttgagaa
1141 ccttagaatg ctgccgcacg cacctggggt ccaaatgcag gcgattcctg aggacgccat
1201 ccctgaggag agtggcgatg aggacgaaga cgaccctgac aagcgcatct cgatctgctc
1261 ctctgacaaa cgaattgcct gtgaggaaga gttctccgat tctgaagagg agggagaggg
1321 gggccgcaag aactcttcca acttcaaaaa agccaagaga gtcaaaacag aggatgaaaa
1381 agagaaagac ccagaggaga agaaagaagt caccgaagag gagaaaacca aggaggagaa
1441 gccagaagcc aaaggggtca aggaggaggt caagttggcc tgaatggacc tctccagctc
1501 tggcttcctg ctgagtccct cacgtttctt ccccaacccc tcagatttta tattttctat
1561 ttctctgtgt atttatataa aaatttatta aatataaata tccccaggga cagaaaccaa
1621 ggccccgagc tcagggcagc tgtgctgggt gagctcttcc aggagccacc ttgccaccca
1681 ttcttcccgt tcttaacttt gaaccataaa gggtgccagg tctgggtgaa agggatactt
1741 ttatgcaacc ataagacaaa ctcctgaaat gccaagtgcc tgcttagtag ctttggaaag
1801 gtgcccttat tgaacattct agaaggggtg gctgggtctt caaggatctc ctgttttttt
1861 caggctccta aagtaacatc agccattttt agattggttc tgttttcgta ccttcccact
1921 ggcctcaagt gagccaagaa acactgcctg ccctctgtct gtcttctcct aattctgcag
1981 gtggaggttg ctagtctagt ttcctttttg agatactatt ttcatttttg tgagcctctt
2041 tgtaataaaa tggtacattt ctataaaaaa aaaaaaaaaa aaaa
//