LOCUS BC000251 1639 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens glycogen synthase kinase 3 beta, mRNA (cDNA clone
MGC:1736 IMAGE:3357620), complete cds.
ACCESSION BC000251
VERSION BC000251.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1639)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1639)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (14-NOV-2000) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 6 Row: a Column: 20
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 21361339.
FEATURES Location/Qualifiers
source 1..1639
/db_xref="H-InvDB:HIT000029461"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:1736 IMAGE:3357620"
/tissue_type="Eye, retinoblastoma"
/clone_lib="NIH_MGC_16"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1639
/gene="GSK3B"
/db_xref="GeneID:2932"
/db_xref="HGNC:HGNC:4617"
/db_xref="MIM:605004"
CDS 233..1534
/gene="GSK3B"
/codon_start=1
/product="glycogen synthase kinase 3 beta"
/protein_id="AAH00251.1"
/db_xref="GeneID:2932"
/db_xref="HGNC:HGNC:4617"
/db_xref="MIM:605004"
/translation="MSGRPRTTSFAESCKPVQQPSAFGSMKVSRDKDGSKVTTVVATP
GQGPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMR
KLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKL
YMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYIC
SRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTP
TREQIREMNPNYTEFKFPQIKAHPWTKDSSGTGHFTSGVRVFRPRTPPEAIALCSRLL
EYTPTARLTPLEACAHSFFDELRDPNVKLPNGRDTPALFNFTTQELSSNPPLATILIP
PHARIQAAASTPTNATAASDANTGDRGQTNNAASASASNST"
BASE COUNT 495 a 366 c 374 g 404 t
ORIGIN
1 atcatctata tgttaaatat ccgtgccgat ctgtcttgaa ggagaaatat atcgcttgtt
61 ttgtttttta tagtatacaa aaggagtgaa aagccaagag gacgaagtct ttttcttttt
121 cttctgtggg agaacttaat gctgcattta tcgttaacct aacaccccaa cataaagaca
181 aaaggaagaa aaggaggaag gaaggaaaag gtgattcgcg aagagagtga tcatgtcagg
241 gcggcccaga accacctcct ttgcggagag ctgcaagccg gtgcagcagc cttcagcttt
301 tggcagcatg aaagttagca gagacaagga cggcagcaag gtgacaacag tggtggcaac
361 tcctgggcag ggtccagaca ggccacaaga agtcagctat acagacacta aagtgattgg
421 aaatggatca tttggtgtgg tatatcaagc caaactttgt gattcaggag aactggtcgc
481 catcaagaaa gtattgcagg acaagagatt taagaatcga gagctccaga tcatgagaaa
541 gctagatcac tgtaacatag tccgattgcg ttatttcttc tactccagtg gtgagaagaa
601 agatgaggtc tatcttaatc tggtgctgga ctatgttccg gaaacagtat acagagttgc
661 cagacactat agtcgagcca aacagacgct ccctgtgatt tatgtcaagt tgtatatgta
721 tcagctgttc cgaagtttag cctatatcca ttcctttgga atctgccatc gggatattaa
781 accgcagaac ctcttgttgg atcctgatac tgctgtatta aaactctgtg actttggaag
841 tgcaaagcag ctggtccgag gagaacccaa tgtttcgtat atctgttctc ggtactatag
901 ggcaccagag ttgatctttg gagccactga ttatacctct agtatagatg tatggtctgc
961 tggctgtgtg ttggctgagc tgttactagg acaaccaata tttccagggg atagtggtgt
1021 ggatcagttg gtagaaataa tcaaggtcct gggaactcca acaagggagc aaatcagaga
1081 aatgaaccca aactacacag aatttaaatt ccctcaaatt aaggcacatc cttggactaa
1141 ggattcgtca ggaacaggac atttcacctc aggagtgcgg gtcttccgac cccgaactcc
1201 accggaggca attgcactgt gtagccgtct gctggagtat acaccaactg cccgactaac
1261 accactggaa gcttgtgcac attcattttt tgatgaatta cgggacccaa atgtcaaact
1321 accaaatggg cgagacacac ctgcactctt caacttcacc actcaagaac tgtcaagtaa
1381 tccacctctg gctaccatcc ttattcctcc tcatgctcgg attcaagcag ctgcttcaac
1441 ccccacaaat gccacagcag cgtcagatgc taatactgga gaccgtggac agaccaataa
1501 tgctgcttct gcatcagctt ccaactccac ctgaacagtc ccgagcagcc agctgcacag
1561 gaaaaaccac cagttacttg agtgtcactc agcaacactg gtcacgtttg gaaagaatat
1621 taaaaaaaaa aaaaaaaaa
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