LOCUS AY574904 1604 bp mRNA linear HUM 01-APR-2005
DEFINITION Homo sapiens regulated in COPD kinase transcript variant 4 mRNA,
complete cds.
ACCESSION AY574904
VERSION AY574904.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1604)
AUTHORS Watanabe,S., Kondo,S., Tanabe,E., Takao,E., Bacon,K.B. and
Encinas,J.A.
TITLE Molecular cloning and characterization of RCK, a MAPK kinase kinase
that specifically phosphorylates MKK4
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 1604)
AUTHORS Watanabe,S., Kondo,S., Tanabe,E., Takao,E., Bacon,K.B. and
Encinas,J.A.
TITLE Direct Submission
JOURNAL Submitted (17-MAR-2004) Research Center Kyoto, Bayer Yakuhin, Ltd.,
6-5-1-3 Kunimidai, Kizucho, Sorakugun, Kyoto 619-0216, Japan
FEATURES Location/Qualifiers
source 1..1604
/db_xref="H-InvDB:HIT000331956"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="2"
/map="2q21.3"
CDS 32..1564
/note="MAPK kinase kinase; RCK"
/codon_start=1
/product="regulated in COPD kinase transcript variant 4"
/protein_id="AAT81413.1"
/translation="MSSMPKPERHAESLLDICHDTNSSPTDLMTVTKNQNIILQSISR
SEEFDQDGDCSHSTLVNEEEDPSGGRQDWQPRTEGVEITVTFPRDVSPPQEMSQEDLK
EKNLINSSLQEWAQAHAVSHPNEIETVELRKKKLTMRPLVLQKEESSRELCNVNLGFL
LPRSCLELNISKSVTREDAPHFLKEQQRKSEEFSTSHMKYSGRSIKRHSSGLRIYDRE
EKFLISNEKKIFSENSLKSEEPILWTKGEILGKGAYGTVYCGLTSQGQLIAVKQVALD
TSNKLAAEKEYRKLQEEVDLLKALKHVNIVAYLGTCLQENTVSIFMEFVPGGSISSII
NRFGPLPEMVFCKYTKQILQGVAYLHENCVVHRDIKGNNVMLMPTGIIKLIDFGCARR
LAWAGLNGTHSDMLKSMHGTPYWMAPEVINESGYGRKSDIWSIGCTVFEMATGKPPLA
SMDRMAAMFYIGAHRGLMPPLPDHFSENAADFVRMCLTRDQHERPSALQLLKHSFLER
SH"
BASE COUNT 492 a 329 c 377 g 406 t
ORIGIN
1 ttcaaagaaa cagcagcttt tggacatttt aatgagttct atgccaaaac cagaaagaca
61 tgctgagtca ttgcttgaca tttgtcatga tacaaactct tctccaactg atttgatgac
121 agttaccaaa aatcaaaaca tcatcttgca aagcatcagc agaagtgagg agttcgacca
181 agatggtgac tgcagtcatt ccacactggt taatgaagaa gaagatccca gtggtggtag
241 acaggactgg caacccagga cagaaggtgt tgagatcact gtaacttttc caagagatgt
301 cagtcctccc caagaaatga gccaagaaga cttaaaagaa aagaatctga taaactcatc
361 gcttcaagaa tgggcacaag cacatgcagt ttctcatcca aatgaaatag aaacggtgga
421 gctcaggaaa aagaagctga ccatgcggcc cttagttttg caaaaagagg aaagttccag
481 ggagctctgc aatgtgaact tgggcttttt gctaccaaga tcttgtttag aactgaacat
541 ttccaagtct gtaaccagag aagatgctcc tcattttctg aaggagcagc aaagaaaatc
601 tgaagagttt tcgacctctc atatgaagta cagtggccga agcatcaaga ggcatagtag
661 tgggctcagg atatatgaca gggaggagaa atttctcatc tcaaatgaaa agaagatatt
721 ttctgaaaat agtttaaagt ctgaagaacc tatcctatgg accaagggtg agattcttgg
781 aaagggagcc tacggcacag tatactgtgg tctcactagt caaggacagc taatagctgt
841 aaaacaggtg gctttggata cctctaataa attagctgct gaaaaggaat accggaaact
901 acaggaagaa gtagatttgc tcaaagcact gaaacatgtc aacattgtgg cctatttggg
961 gacatgcttg caagagaaca ctgtgagcat tttcatggag tttgttcctg gtggctcaat
1021 ctctagtatt ataaaccgtt ttgggccatt gcctgagatg gtgttctgta aatatacgaa
1081 acaaatactt caaggtgttg cttatctcca tgagaactgt gtggtacatc gcgatatcaa
1141 aggaaataat gttatgctca tgccaactgg aataataaag ctgattgact ttggctgtgc
1201 caggcgtttg gcctgggcag gtttaaatgg cacccacagt gacatgctta agtccatgca
1261 tgggactcca tattggatgg ccccagaagt catcaatgag tctggctatg gacggaaatc
1321 agatatctgg agcattggtt gtactgtgtt tgagatggct acagggaagc ctccactggc
1381 ttccatggac aggatggccg ccatgtttta catcggagca caccgagggc tgatgcctcc
1441 tttaccagac cacttctcag aaaatgcagc agactttgtg cgcatgtgcc tgaccaggga
1501 ccagcatgag cgaccttctg ctctccagct cctgaagcac tccttcttgg agagaagtca
1561 ctgaatatac atcaagactt tcttcccagt tccactgcag atgc
//