LOCUS       AY429111                2295 bp    mRNA    linear   HUM 03-NOV-2003
DEFINITION  Homo sapiens thyroid stimulating hormone receptor mRNA, complete
            cds.
ACCESSION   AY429111
VERSION     AY429111.1
KEYWORDS    .
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2295)
  AUTHORS   Kopatz,S.A., Aronstam,R.S. and Sharma,S.V.
  TITLE     Isolation of cDNA coding for thyroid stimulating hormone receptor
            (TSHR)
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 2295)
  AUTHORS   Kopatz,S.A., Aronstam,R.S. and Sharma,S.V.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2003) Guthrie cDNA Resource Center, Guthrie
            Research Institute, 1 Guthrie Square, Sayre, PA 18840, USA
FEATURES             Location/Qualifiers
     source          1..2295
                     /db_xref="H-InvDB:HIT000254599"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /tissue_type="thyroid"
     CDS             1..2295
                     /note="G-protein coupled receptor; TSHR"
                     /codon_start=1
                     /product="thyroid stimulating hormone receptor"
                     /protein_id="AAR07906.1"
                     /translation="MRPADLLQLVLLLDLPRDLGGMGCSSPPCECHQEEDFRVTCKDI
                     QRIPSLPPSTQTLKLIETHLRTIPSHAFSNLPNISRIYVSIDVTLQQLESHSFYNLSK
                     VTHIEIRNTRNLTYIDPDALKELPLLKFLGIFNTGLKMFPDLTKVYSTDIFFILEITD
                     NPYMTSIPVNAFQGLCNETLTLKLYNNGFTSVQGYAFNGTKLDAVYLNKNKYLTVIDK
                     DAFGGVYSGPSLLDVSQTSVTALPSKGLEHLKELIARNTWTLKKLPLSLSFLHLTRAD
                     LSYPSHCCAFKNQKKIRGILESLMCNESSMQSLRQRKSVNALNSPLHQEYEENLGDSI
                     VGYKEKSKFQDTHNNAHYYVFFEEQEDEIIGFGQELKNPQEETLQAFDSHYDYTICGD
                     SEDMVCTPKSDEFNPCEDIMGYKFLRIVVWFVSLLALLGNVFVLLILLTSHYKLNVPR
                     FLMCNLAFADFCMGMYLLLIASVDLYTHSEYYNHAIDWQTGPGCNTAGFFTVFASELS
                     VYTLTVITLERWYAITFAMRLDRKIRLRHACAIMVGGWVCCFLLALLPLVGISSYAKV
                     SICLPMDTETPLALAYIVFVLTLNIVAFVIVCCCYVKIYITVRNPQYNPGDKDTKIAK
                     RMAVLIFTDFICMAPISFYALSAILNKPLITVSNSKILLVLFYPLNSCANPFLYAIFT
                     KAFQRDVFILLSKFGICKRQAQAYRGQRVPPKNSTDIQVQKVTHDMRQGLHNMEDVYE
                     LIENSHLTPKKQGQISEEYMQTVL"
BASE COUNT          599 a          599 c          498 g          599 t
ORIGIN      
        1 atgaggccgg cggacttgct gcagctggtg ctgctgctcg acctgcccag ggacctgggc
       61 ggaatggggt gttcgtctcc accctgcgag tgccatcagg aggaggactt cagagtcacc
      121 tgcaaggata ttcaacgcat ccccagctta ccgcccagta cgcagactct gaagcttatt
      181 gagactcacc tgagaactat tccaagtcat gcattttcta atctgcccaa tatttccaga
      241 atctacgtat ctatagatgt gactctgcag cagctggaat cacactcctt ctacaatttg
      301 agtaaagtga ctcacataga aattcggaat accaggaact taacttacat agaccctgat
      361 gccctcaaag agctccccct cctaaagttc cttggcattt tcaacactgg acttaaaatg
      421 ttccctgacc tgaccaaagt ttattccact gatatattct ttatacttga aattacagac
      481 aacccttaca tgacgtcaat ccctgtgaat gcttttcagg gactatgcaa tgaaaccttg
      541 acactgaagc tgtacaacaa tggctttact tcagtccaag gatatgcttt caatgggaca
      601 aagctggatg ctgtttacct aaacaagaat aaatacctga cagttattga caaagatgca
      661 tttggaggag tatacagtgg accaagcttg ctggacgtgt ctcaaaccag tgtcactgcc
      721 cttccatcca aaggcctgga gcacctgaag gaactgatag caagaaacac ctggactctt
      781 aagaaacttc cactttcctt gagtttcctt cacctcacac gggctgacct ttcttaccca
      841 agccactgct gtgcttttaa gaatcagaag aaaatcagag gaatccttga gtccttgatg
      901 tgtaatgaga gcagtatgca gagcttgcgc cagagaaaat ctgtgaatgc cttgaatagc
      961 cccctccacc aggaatatga agagaatctg ggtgacagca ttgttgggta caaggaaaag
     1021 tccaagttcc aggatactca taacaacgct cattattacg tcttctttga agaacaagag
     1081 gatgagatca ttggttttgg ccaggagctc aaaaaccccc aggaagagac tctacaagct
     1141 tttgacagcc attatgacta caccatatgt ggggacagtg aagacatggt gtgtaccccc
     1201 aagtccgatg agttcaaccc gtgtgaagac ataatgggct acaagttcct gagaattgtg
     1261 gtgtggttcg ttagtctgct ggctctcctg ggcaatgtct ttgtcctgct tattctcctc
     1321 accagccact acaaactgaa cgtcccccgc tttctcatgt gcaacctggc ctttgcggat
     1381 ttctgcatgg ggatgtacct gctcctcatc gcctctgtag acctctacac tcactctgag
     1441 tactacaacc atgccatcga ctggcagaca ggccctgggt gcaacacggc tggtttcttc
     1501 actgtctttg caagcgagtt atcggtgtat acgctgacgg tcatcaccct ggagcgctgg
     1561 tatgccatca ccttcgccat gcgcctggac cggaagatcc gcctcaggca cgcatgtgcc
     1621 atcatggttg ggggctgggt ttgctgcttc cttctcgccc tgcttccttt ggtgggaata
     1681 agtagctatg ccaaagtcag tatctgcctg cccatggaca ccgagacccc tcttgctctg
     1741 gcatatattg tttttgttct gacgctcaac atagttgcct tcgtcatcgt ctgctgctgt
     1801 tatgtgaaga tctacatcac agtccgaaat ccgcagtaca acccagggga caaagatacc
     1861 aaaattgcca agaggatggc tgtgttgatc ttcaccgact tcatatgcat ggccccaatc
     1921 tcattctatg ctctgtcagc aattctgaac aagcctctca tcactgttag caactccaaa
     1981 atcttgctgg tactcttcta tccacttaac tcctgtgcca atccattcct ctatgctatt
     2041 ttcaccaagg ccttccagag ggatgtgttc atcctactca gcaagtttgg catctgtaaa
     2101 cgccaggctc aggcataccg ggggcagagg gttcctccaa agaacagcac tgatattcag
     2161 gttcaaaagg ttacccacga catgaggcag ggtctccaca acatggaaga tgtctatgaa
     2221 ctgattgaaa actcccatct aaccccaaag aagcaaggcc aaatctcaga agagtatatg
     2281 caaacggttt tgtaa
//