LOCUS       AY376402                3357 bp    mRNA    linear   HUM 06-MAY-2008
DEFINITION  Homo sapiens solute carrier family 4 sodium bicarbonate
            cotransporter-like member 10 (SLC4A10) mRNA, complete cds.
ACCESSION   AY376402
VERSION     AY376402.1
KEYWORDS    .
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3357)
  AUTHORS   Parker,M.D., Musa-Aziz,R., Rojas,J.D., Choi,I., Daly,C.M. and
            Boron,W.F.
  TITLE     Characterization of human SLC4A10 as an electroneutral Na/HCO3
            cotransporter (NBCn2) with Cl- self-exchange activity
  JOURNAL   J. Biol. Chem. 283 (19), 12777-12788 (2008)
   PUBMED   18319254
REFERENCE   2  (bases 1 to 3357)
  AUTHORS   Choi,I., Kobayashi,C., Rojas,J.R. and Boron,W.F.
  TITLE     Cloning and functional characterisation of human kidney 'NCBE'
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 3357)
  AUTHORS   Choi,I., Kobayashi,C., Rojas,J.R. and Boron,W.F.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2003) Cellular and Molecular Physiology, Yale
            University, 333 Cedar Street, New Haven, CT 06520-8026, USA
FEATURES             Location/Qualifiers
     source          1..3357
                     /db_xref="H-InvDB:HIT000253403"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2q23-q24"
                     /tissue_type="kidney"
     gene            1..3357
                     /gene="SLC4A10"
     CDS             1..3357
                     /gene="SLC4A10"
                     /codon_start=1
                     /product="solute carrier family 4 sodium bicarbonate
                     cotransporter-like member 10"
                     /protein_id="AAQ83632.1"
                     /translation="MEIKDQGAQMEPLLPTRNDEEAVVDRGGTRSILKTHFEKEDLEG
                     HRTLFIGVHVPLGGRKSHRRHRHRGHKHRKRDRERDSGLEDGRESPSFDTPSQRVQFI
                     LGTEDDDEEHIPHDLFTELDEICWREGEDAEWRETARWLKFEEDVEDGGERWSKPYVA
                     TLSLHSLFELRSCILNGTVLLDMHANTLEEIADMVLDQQVSSGQLNEDVRHRVHEALM
                     KQHHHQNQKKLTNRIPIVRSFADIGKKQSEPNSMDKNAGQVVSPQSAPACVENKNDVS
                     RENSTVDFSKGLGGQQKGHTSPCGMKQRHEKGPPHQQEREVDLHFMKKIPPGAEASNI
                     LVGELEFLDRTVVAFVRLSPAVLLQGLAEVPIPTRFLFILLGPLGKGQQYHEIGRSIA
                     TLMTDEVFHDVAYKAKDRNDLVSGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKR
                     KIPAVPNGTAAHGEAEPHGGHSGPELQRTGRIFGGLILDIKRKAPYFWSDFRDAFSLQ
                     CLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFGGQPLTIL
                     GSTGPVLVFEKILFKFCKEYGLSYLSLRASIGLWTATLCIILVATDASSLVCYITRFT
                     EEAFASLICIIFIYEALEKLFELSEAYPINMHNDLELLTQYSCNCVEPHNPSNGTLKE
                     WRESNISASDIIWENLTVSECKSLHGEYVGRACGHDHPYVPDVLFWSVILFFSTVTLS
                     ATLKQFKTSRYFPTKVRSIVSDFAVFLTILCMVLIDYAIGIPSPKLQVPSVFKPTRDD
                     RGWFVTPLGPNPWWTVIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDL
                     LMVAVMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTGL
                     MIFILMGSSVFMTSILKFIPMPVLYGVFLYMGASSLKGIQFFDRIKLFWMPAKHQPDF
                     IYLRHVPLRKVHLFTIIQMSCLGLLWIIKVSRAAIVFPMMVLALVFVRKLMDLLFTKR
                     ELSWLDDLMPESKKKKLEDAEKEEEQSMLAMEDEGTVQLPLEGHYRDDPSVINISDEM
                     SKTALWRNLLITADNSKDKESSFPSKSSPS"
BASE COUNT          958 a          668 c          802 g          929 t
ORIGIN      
        1 atggagatta aagaccaggg agcccaaatg gagccgctgc tgcctacgag aaatgatgaa
       61 gaagcagttg tggatagagg tggaactcgt tctattctca aaacacactt tgagaaagaa
      121 gatttagaag gtcatcgaac actatttatt ggagtacatg tgcccttggg aggaagaaaa
      181 agccatcgac gtcacaggca tcgtggtcat aaacacagaa agagagacag agaaagagat
      241 tcaggattag aggatggaag ggagtcacct tcttttgaca ccccatcaca gagggtacag
      301 tttattcttg gaaccgagga tgatgacgag gaacacattc ctcatgacct tttcacagaa
      361 ctggatgaga tttgttggcg tgaaggtgag gacgctgagt ggcgagaaac agccaggtgg
      421 ttgaagtttg aagaagatgt ggaagatgga ggagaaaggt ggagcaagcc ttatgtggct
      481 actctttcat tgcacagctt gtttgaattg agaagttgta ttctgaatgg aactgtgttg
      541 ctggacatgc atgccaacac tttagaagaa attgcagata tggttcttga ccaacaagtg
      601 agctcaggtc agctgaatga agatgtacgc catagggtcc atgaggcatt gatgaaacag
      661 catcatcatc agaatcagaa aaaactcacc aacaggattc ccattgttcg ttcctttgct
      721 gatattggca agaaacagtc agaaccaaat tccatggaca aaaatgcagg tcaggttgtt
      781 tctcctcagt ctgctccagc ctgtgttgaa aataaaaatg atgttagcag agaaaacagc
      841 actgttgact ttagcaaggg actgggaggc caacaaaagg ggcatactag tccatgtggg
      901 atgaaacaaa ggcatgaaaa aggacctcca caccagcaag agagagaggt tgatctgcat
      961 tttatgaaaa agattcctcc aggtgctgaa gcatcgaaca tcttagtggg ggaactggag
     1021 ttcttggatc gaacagtagt tgcgtttgtc aggttgtctc cagctgtatt gcttcaagga
     1081 ctggctgaag tcccaatccc aaccagattt ttgttcattc ttctgggacc cctgggaaag
     1141 ggtcaacagt accatgagat tggcagatca attgcaaccc taatgacaga tgaggtattt
     1201 catgatgttg cctataaagc taaagatcgt aatgacttgg tatcaggaat tgatgagttt
     1261 ctggatcagg ttactgttct ccctcctgga gaatgggatc caagcattcg aatagagcct
     1321 cccaaaaatg ttccttccca ggagaagagg aagattcctg ctgtaccaaa tggaacagca
     1381 gctcatgggg aagcagagcc ccacggagga catagtggac ctgaactcca gcgaactgga
     1441 aggatttttg ggggacttat tttagatatc aaaagaaaag ctccatactt ctggagtgac
     1501 ttcagagatg ctttcagcct gcagtgctta gcatcttttc tatttctcta ctgcgcgtgt
     1561 atgtctcctg tcatcacgtt tggaggactg ctgggagaag caactgaagg gcgtataagt
     1621 gcaattgaat ctctctttgg agcatccatg accgggatag cctattctct ctttggtgga
     1681 cagcctctta ccatattagg cagtacagga ccagttttgg tgtttgaaaa gattttgttt
     1741 aaattttgca aagaatatgg gctgtcatac ctatctttaa gagctagcat tggactttgg
     1801 actgcaactc tatgtatcat acttgtggcc acagatgcta gttcccttgt ctgctacatc
     1861 actcggttta ctgaagaagc ttttgcttcc ctgatttgca tcattttcat ttatgaggcc
     1921 ctggagaagt tgtttgaact cagtgaagca tatccaatca acatgcataa tgatctggaa
     1981 ctgctgacac aatactcgtg taactgtgtg gaaccgcata atcccagcaa tggcacattg
     2041 aaggaatgga gggaatccaa tatttctgcc tctgacataa tttgggagaa cctaactgtg
     2101 tcagaatgca aatcattgca tggagagtat gttggacggg cctgtggcca tgatcaccca
     2161 tatgttccag atgttctatt ttggtctgtg atcctgttct tttccacagt tactctgtca
     2221 gccaccctga agcagttcaa gactagcaga tattttccaa ccaaggttcg atccatagtg
     2281 agtgactttg cggtctttct tacaattctg tgtatggttt taattgacta tgccattggg
     2341 atcccatctc caaaactaca agtaccaagt gttttcaagc ccactagaga tgatcgtggc
     2401 tggtttgtta cgcctttagg tccaaaccca tggtggacag taatagctgc tataattcca
     2461 gctctgcttt gtactattct aatttttatg gaccaacaga ttacagctgt catcatcaac
     2521 aggaaagagc ataagctaaa gaaaggttgc gggtaccatc tggacctatt aatggtggct
     2581 gtcatgctcg gtgtatgctc catcatgggc ctgccatggt ttgtggctgc cacagtcctc
     2641 tccatcactc atgtcaatag cctaaaactg gaatcagaat gctcagctcc aggagaacaa
     2701 cccaaatttc tcggcattcg ggagcaaagg gttactgggc ttatgatttt tattcttatg
     2761 ggttcatcag tctttatgac cagtattctg aagtttattc ccatgccagt gctatatgga
     2821 gtgtttcttt atatgggtgc ttcatctcta aagggaattc agttctttga taggataaag
     2881 ctcttctgga tgccggcaaa acatcaacca gattttatat acctaaggca cgtaccgctt
     2941 cgaaaagtgc atctcttcac aattattcag atgagttgcc ttggcctttt gtggataata
     3001 aaagtttcaa gagctgctat tgtctttccc atgatggtgt tagccctggt atttgtaaga
     3061 aagttgatgg acttgttgtt cacgaagcgg gaactcagct ggttggatga tttgatgccc
     3121 gagagtaaga aaaagaaact ggaagatgct gaaaaagaag aagaacaaag tatgctagct
     3181 atggaagatg agggcacagt acaactccca ttggaagggc actatagaga tgatccatct
     3241 gtgatcaata tatctgatga aatgtcaaag actgccttgt ggaggaacct tctgattact
     3301 gccgataact caaaagataa ggagtcaagc tttccttcca aaagctcccc ttcctaa
//