LOCUS AH005712 1920 bp DNA linear HUM 10-JUN-2016
DEFINITION Homo sapiens chromosome 13 insulin promoter factor 1 (PDX1) gene,
complete cds.
ACCESSION AH005712 AF035259 AF035260
VERSION AH005712.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1920)
AUTHORS Hara,M., Lindner,T.H., Paz,V.P., Wang,X., Iwasaki,N. and Bell,G.I.
TITLE Mutations in the pancreatic and duodenal homeobox gene (PDX1) are
not a common cause of MODY/Early-onset Type 2 diabetes in Japanese
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 1920)
AUTHORS Hara,M., Lindner,T.H., Paz,V.P., Wang,X., Iwasaki,N. and Bell,G.I.
TITLE Direct Submission
JOURNAL Submitted (19-NOV-1997) Biochemistry, Molecular Biology, and
Medicine, The University of Chicago, Howard Hughes Medical
Institute, 5841 South Maryland Avenue, MC1028, Chicago, IL 60637,
USA
COMMENT On or before Jun 10, 2016 this sequence version replaced
AF035259.1, AF035260.1, AH005712.1.
FEATURES Location/Qualifiers
source 1..1920
/organism="Homo sapiens"
/mol_type="genomic DNA"
/db_xref="taxon:9606"
/chromosome="13"
/map="13q12.1"
/clone_lib="PAC library, Genome Systems Inc."
gene <283..1920
/gene="PDX1"
/note="pancreatic and duodenal homeobox gene"
mRNA join(<283..688,1326..1920)
/gene="PDX1"
/product="insulin promoter factor 1"
CDS join(283..688,1326..1771)
/gene="PDX1"
/note="IPF1; transcription factor"
/codon_start=1
/product="insulin promoter factor 1"
/protein_id="AAB88463.1"
/translation="MNGEEQYYAATQLYKDPCAFQRGPAPEFSASPPACLYMGRQPPP
PPPHPFPGALGALEQGSPPDISPYEVPPLADDPAVAHLHHHLPAQLALPHPPAGPFPE
GAEPGVLEEPNRVQLPFPWMKSTKAHAWKGQWAGGAYAAEPEENKRTRTAYTRAQLLE
LEKEFLFNKYISRPRRVELAVMLNLTERHIKIWFQNRRMKWKKEEDKKRGGGTAVGGG
GVAEPEQDCAVTSGEELLALPPPPPPGGAVPPAAPVAAREGRLPPGLSASPQPSSVAP
RRPQEPR"
exon <283..688
/gene="PDX1"
/number=1
intron 689..>992
/gene="PDX1"
/number=1
gap 993..1092
/estimated_length=unknown
intron <1093..1325
/gene="PDX1"
/note="size=3.8 kb"
/number=1
exon 1326..1920
/gene="PDX1"
/number=2
BASE COUNT 293 a 649 c 593 g 285 t
ORIGIN
1 gcaggtgctc gcgggtacct gggcctagcc tcttagtgcg gccagccagg ccaatcacgg
61 cccccggctg aaccacgtgg ggccccgcgg agcctatggt gcggcggccg gcccgccggt
121 ccgcgctggc tgtgggttcc ctctgagatc agtgcggagc tgtcaaagcg agcagggtgg
181 cgccgggagt gggaacgcca cacagtgcca aatccccggc tccagctccc gactcccggc
241 tcccggctcc cggctcccgg tgcccaatcc cgggccgcag ccatgaacgg cgaggagcag
301 tactacgcgg ccacgcagct ttacaaggac ccatgcgcgt tccagcgagg cccggcgccg
361 gagttcagcg ccagcccccc tgcgtgcctg tacatgggcc gccagccccc gccgccgccg
421 ccgcacccgt tccctggcgc cctgggcgcg ctggagcagg gcagcccccc ggacatctcc
481 ccgtacgagg tgccccccct cgccgacgac cccgcggtgg cgcaccttca ccaccacctc
541 ccggctcagc tcgcgctccc ccacccgccc gccgggccct tcccggaggg agccgagccg
601 ggcgtcctgg aggagcccaa ccgcgtccag ctgcctttcc catggatgaa gtctaccaaa
661 gctcacgcgt ggaaaggcca gtgggcaggt aagcctggct ccccacccct ttctcctttc
721 cggttctcac ccggccgcct tacctccaag cgctcccagg agccttctct ctgttcccgg
781 cgccttggat tatcccgggt cggactaaac tacatcaggg agctaccgag cccatccctc
841 acagcagtgc ttctctagtc cagtttgaag catctttccc acccagctct cctgggagtg
901 tacactcctt ccttccctgt tcgctgagcc catcttcgcc ccaggagccc gcgctgccag
961 cgccatcctt agagagccga ggctgagtcc tgnnnnnnnn nnnnnnnnnn nnnnnnnnnn
1021 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
1081 nnnnnnnnnn nntcgagttt ggtctccaat aaaaaggcta tctttattag gaagggcttg
1141 agttactagg gaagagcttc gcgcgcctac actaggcgct gaaatgggat gctggggctt
1201 ggtggctccg gcgggagcag ctggtagggc tagggctccc tggcccccct tgaaggggtt
1261 gggctgcgtg ggtgggggct gtgcggggct ccgggggcca cactcacgcc ctgtgtcgcc
1321 cgcaggcggc gcctacgctg cggagccgga ggagaacaag cggacgcgca cggcctacac
1381 gcgcgcacag ctgctagagc tggagaagga gttcctattc aacaagtaca tctcacggcc
1441 gcgccgggtg gagctggctg tcatgttgaa cttgaccgag agacacatca agatctggtt
1501 ccaaaaccgc cgcatgaagt ggaaaaagga ggaggacaag aagcgcggcg gcgggacagc
1561 tgtcgggggt ggcggggtcg cggagcctga gcaggactgc gccgtgacct ccggcgagga
1621 gcttctggcg ctgccgccgc cgccgccccc cggaggtgct gtgccgcccg ctgcccccgt
1681 tgccgcccga gagggccgcc tgccgcctgg ccttagcgcg tcgccacagc cctccagcgt
1741 cgcgcctcgg cggccgcagg aaccacgatg agaggcagga gctgctcctg gctgaggggc
1801 ttcaaccact cgccgaggag gagcagaggg cctaggagga ccccgggcgt ggaccacccg
1861 ccctggcagt tgaatggggc ggcaattgcg gggcccacct tagaccgaag gggaaaaccc
//