LOCUS AH002938 6016 bp DNA linear HUM 01-AUG-2016
DEFINITION Homo sapiens phosphoglycerate kinase (PGK1) gene, complete cds.
ACCESSION AH002938 M11958 M11959 M11960 M11961 M11962 M11963 M11964 M11965
M11966 M11967 M11968
VERSION AH002938.2
KEYWORDS phosphoglycerate kinase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 406 to 853; 954 to 1380; 1481 to 1804; 1905 to 2344; 2445
to 2866; 2967 to 3308; 3409 to 3659; 3760 to 4124; 4225 to 4623;
4724 to 5111; 5212 to 6016)
AUTHORS Michelson,A.M., Blake,C.C., Evans,S.T. and Orkin,S.H.
TITLE Structure of the human phosphoglycerate kinase gene and the
intron-mediated evolution and dispersal of the nucleotide-binding
domain
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 82 (20), 6965-6969 (1985)
PUBMED 2995995
REFERENCE 2 (bases 1 to 853)
AUTHORS Michelson,A.M., Blake,C.C.F., Evans,T.S. and Orkin,S.H.
JOURNAL Unpublished
COMMENT On or before Aug 1, 2016 this sequence version replaced M11958.1,
M11959.1, M11960.1, M11961.1, M11962.1, M11963.1, M11964.1,
M11965.1, M11966.1, M11967.1, M11968.1, AH002938.1.
FEATURES Location/Qualifiers
source 1..6016
/organism="Homo sapiens"
/mol_type="genomic DNA"
/db_xref="taxon:9606"
/map="Xq13.3"
gene 530..5294
/gene="PGK1"
CDS join(530..594,1146..1196,1557..1712,2024..2168,2624..2727,
3028..3147,3475..3589,3868..4047,4405..4582,4806..4904,
5254..5294)
/gene="PGK1"
/note="phosphoglycerate kinase"
/codon_start=1
/protein_id="AAA60079.1"
/translation="MSLSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAV
PSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEPVAVELKSLLGKDVLFLKDCVGP
EVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDV
YVNDAFGTAHRAHSSMVGVNLPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVA
DKIQLINNMLDKVNEMIIGGGMAFTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKN
GVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGPESSKKYAEAVTRAKQI
VWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHV
STGGGASLELLEGKVLPGVDALSNI"
prim_transcript <530..>853
/gene="PGK1"
/note="PGK mRNA"
exon <530..594
/gene="PGK1"
/note="phosphoglycerate kinase; G00-120-282"
/number=1
intron 595..>853
/gene="PGK1"
/note="PGK intron A"
gap 854..953
/estimated_length=unknown
prim_transcript <954..>1380
/gene="PGK1"
/note="PGK mRNA"
intron <954..1145
/gene="PGK1"
/note="PGK intron A"
exon 1146..1196
/gene="PGK1"
/note="G00-120-282"
/number=2
intron 1197..>1380
/gene="PGK1"
/note="PGK intron B"
gap 1381..1480
/estimated_length=unknown
prim_transcript <1481..>1804
/gene="PGK1"
/note="PGK mRNA"
intron <1481..1556
/gene="PGK1"
/note="PGK intron B"
exon 1557..1712
/gene="PGK1"
/note="G00-120-282"
/number=3
intron 1713..>1804
/gene="PGK1"
/note="PGK intron C"
gap 1805..1904
/estimated_length=unknown
prim_transcript <1905..>2344
/gene="PGK1"
/note="PGK mRNA"
intron <1905..2023
/gene="PGK1"
/note="PGK intron C"
exon 2024..2168
/gene="PGK1"
/note="G00-120-282"
/number=4
intron 2169..>2344
/gene="PGK1"
/note="PGK intron D"
gap 2345..2444
/estimated_length=unknown
prim_transcript <2445..>2866
/gene="PGK1"
/note="PGK mRNA"
intron <2445..2623
/gene="PGK1"
/note="PGK intron D"
exon 2624..2727
/gene="PGK1"
/note="G00-120-282"
/number=5
intron 2728..>2866
/gene="PGK1"
/note="PGK intron E"
gap 2867..2966
/estimated_length=unknown
prim_transcript <2967..>3308
/gene="PGK1"
/note="PGK mRNA"
intron <2967..3027
/gene="PGK1"
/note="PGK intron E"
exon 3028..3147
/gene="PGK1"
/note="G00-120-282"
/number=6
intron 3148..>3308
/gene="PGK1"
/note="PGK intron F"
gap 3309..3408
/estimated_length=unknown
prim_transcript <3409..>3659
/gene="PGK1"
/note="PGK mRNA"
intron <3409..3474
/gene="PGK1"
/note="PGK intron F"
exon 3475..3589
/gene="PGK1"
/note="G00-120-282"
/number=7
intron 3590..>3659
/gene="PGK1"
/note="PGK intron G"
gap 3660..3759
/estimated_length=unknown
prim_transcript <3760..>4124
/gene="PGK1"
/note="PGK mRNA"
intron <3760..3867
/gene="PGK1"
/note="PGK intron G"
exon 3868..4047
/gene="PGK1"
/note="G00-120-282"
intron 4048..>4124
/gene="PGK1"
/note="PGK intron H"
gap 4125..4224
/estimated_length=unknown
prim_transcript <4225..>4623
/gene="PGK1"
/note="PGK mRNA"
intron <4225..4404
/gene="PGK1"
/note="PGK intron H"
exon 4405..4582
/gene="PGK1"
/note="G00-120-282"
/number=9
intron 4583..>4623
/gene="PGK1"
/note="PGK intron I"
gap 4624..4723
/estimated_length=unknown
prim_transcript <4724..>5111
/gene="PGK1"
/note="PGK mRNA"
intron <4724..4805
/gene="PGK1"
/note="PGK intron I"
exon 4806..4904
/gene="PGK1"
/note="G00-120-282"
/number=10
intron 4905..>5111
/gene="PGK1"
/note="PGK intron J"
gap 5112..5211
/estimated_length=unknown
prim_transcript <5212..5728
/note="PGK mRNA"
intron <5212..5253
/gene="PGK1"
/note="PGK intron J"
exon 5254..>5294
/gene="PGK1"
/note="phosphoglycerate kinase; G00-120-282"
/number=11
BASE COUNT 1196 a 1070 c 1263 g 1487 t
ORIGIN 516 bp upstream of PvuII site; chromosome Xq13-q21.1.
1 tccacggggt tggggttgcg ccttttccaa ggcagccctg ggtttgcgca gggacgcggc
61 tgctctgggc gtggttccgg gaaacgcagc ggcgccgacc ctgggtctcg cacattcttc
121 acgtccgttc gcagcgtcac ccggatcttc gccgctaccc ttgtgggccc cccggcgacg
181 cttcctgctc cgcccctaag tcgggaaggt tccttgcggt tcgcggcgtg ccggacgtga
241 caaacggaag ccgcacgtct cactagtacc ctcgcagacg gacagcgcca gggagcaatg
301 gcagcgcgcc gaccgcgatg ggctgtggcc aatagcggct gctcagcggg gcgcgccgag
361 agcagcggcc gggaaggggc ggtgcgggag gcggggtgtg gggcggtagt gtgggccctg
421 ttcctgcccg cgcggtgttc cgcattctgc aagcctccgg agcgcacgtc ggcagtcggc
481 tccctcgttg accgaatcac cgacctctct ccccagctgt atttccaaaa tgtcgctttc
541 taacaagctg acgctggaca agctggacgt taaagggaag cgggtcgtta tgaggtaatt
601 ctgcacgttt gcccgcgtgc tctctgtgct ctgtcgcaaa cctctttggc cggagccgac
661 ttgttctctc gtctgctcta agttctttta gcttttggct gggccccaag ggtcctaggc
721 ttggagggcg aggctgctca cgggtttggt ggtttctagc cgcattttcc ccagcccaga
781 aagcacccga agtcaccctt cgggatggat cccactgagg aagggctgag attgccgctg
841 ggacccattt tgtnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
901 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnntggtgtc
961 gttaccccag tcaccactcc cgccatcctc cccatgacta accactattt tgacttttaa
1021 tgccactgat tatttttaag atgagatttg aatttctgac ttatttaact ggttcattaa
1081 aaatgcatct cctagtcttt gatggaacag taagttgatc atggtcttgc atctttcttt
1141 tttagagtcg acttcaatgt tcctatgaag aacaaccaga taacaaacaa ccagaggtaa
1201 ggtccctgct aatccttggg ctgggtttaa gatgtgtgta ggtacacagg atgaaatgtt
1261 tttcctttca tattgtatta tggaactgta gcaacttaaa acaaatgatt ttggctttct
1321 atcaacccac tctctgattc gctttcttat ttatgagaat atacaaatat aagcaaaatc
1381 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
1441 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn atgaggttac aataagctag
1501 tcccactagt ttctaggagt aacttctttc tgtttgttgt ctctctttgg ttgcaggatt
1561 aaggctgctg tcccaagcat caaattctgc ttggacaatg gagccaagtc ggtagtcctt
1621 atgagccacc taggccggcc tgatggtgtg cccatgcctg acaagtactc cttagagcca
1681 gttgctgtag aactcaaatc tctgctgggc aagtaagtgc caggctctgg tgctggtaga
1741 ctttgtggcg ggggaagttg tcaagcacgt tgttactggt ttttaacttc atactgctca
1801 agtgnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
1861 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnncaagta agtgccaggc
1921 tctggtgctg gtagactttg tggcggggga agttgtcaag cacgttgtta ctggttttta
1981 actttcatac tgctcaagtg tcttcatctc ttcctcttct cagggatgtt ctgttcttga
2041 aggactgtgt aggcccagaa gtggagaaag cctgtgccaa cccagctgct gggtctgtca
2101 tcctgctgga gaacctccgc tttcatgtgg aggaagaagg gaagggaaaa gatgcttctg
2161 ggaacaaggt aggacctgtg attttgacat tattgggggt gagggcctga gtctgtaaga
2221 gactgtggtt gaagaataga gaaagctcat ttattttaac ttagacacct ttattgaagc
2281 atacaatgcc gacacagctt gatgggttat ctcaaagtaa acacacttgt gtaaccacca
2341 cccannnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
2401 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnaatgac caaagtatct
2461 ggaatatttg gaagaaagaa cacatcctac tgctggttgt aaaaaatcgc tgtcccacct
2521 actcagggtc tttagagatg ttcaagagga ctcttggtgt atgaaatgct tttatagttg
2581 tctttggagc catcacattt tctgtttttg tttttctcta taggttaaag ccgagccagc
2641 caaaatagaa gctttccgag cttcactttc caagctaggg gatgtctatg tcaatgatgc
2701 ttttggcact gctcacagag cccacaggta ccaagaacct tgtagactac cacactgaga
2761 acagtattcc tatttacttg agtagcccaa gctctgggtt gtttttggag agttttgtat
2821 tatactgtaa tcctttcagc ttctctaatt ggaactgcca ctatggnnnn nnnnnnnnnn
2881 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
2941 nnnnnnnnnn nnnnnnnnnn nnnnnnctag gatctaggag gaatgatagg gattgactag
3001 aatctgaatg tctttgatct tttctagctc catggtagga gtcaatctgc cacagaaggc
3061 tggtgggttt ttgatgaaga aggagctgaa ctactttgca aaggccttgg agagcccaga
3121 gcgacccttc ctggccatcc tgggcgggta tgaagaactc tttaagatca tgctctaagt
3181 attgtttgcc tggtagtagg ccataacttg ggtggtttat tgtcatatag ctcagtcaca
3241 ctgggtaact gaggagaatt taataaagga actacaggct gggcatggtg gctcacacct
3301 gtaatcccnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
3361 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnntt tctatgtaat
3421 accacttctc tagtccattc ttctttaagt gatgattctt gctttctctt gtagagctaa
3481 agttgcagac aagatccagc tcatcaataa tatgctggac aaagtcaatg agatgattat
3541 tggtggtgga atggctttta ccttccttaa ggtgctcaac aacatggagg taggaaacaa
3601 atgccaagtg gatgtgaaat agctctccat gataatagca ggttgtataa atgtaaaaan
3661 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
3721 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnt tgcattgttc ctttatattg
3781 tattgtgtct ggttcctgtc tgctttgtga ggcagtcttg ttcttagtat agatgctgac
3841 ctccatcatt ttggctcccc tgtgtagatt ggcacttctc tgtttgatga agagggagcc
3901 aagattgtca aagacctaat gtccaaagct gagaagaatg gtgtgaagat taccttgcct
3961 gttgactttg tcactgctga caagtttgat gagaatgcca agactggcca agccactgtg
4021 gcttctggca tacctgctgg ctggatggtg agtcacttga gtgggttggt agtgtgagtg
4081 aacagaaact ctgtggtgtc atttgttcat tgattcagcc aatcnnnnnn nnnnnnnnnn
4141 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
4201 nnnnnnnnnn nnnnnnnnnn nnnnatcttc catacagtag aatttttgag tataaagggc
4261 atgaacaggt ttataaagac tgaagggtac tatttgtttc tagaagaaac tttggtgtgc
4321 agccctgagt tctggtcttg gtggaggtgg tgtttaagta gcttttcttg atagctcatc
4381 ttctctttca cctctacccc tcagggcttg gactgtggtc ctgaaagcag caagaagtat
4441 gctgaggctg tcactcgggc taagcagatt gtgtggaatg gtcctgtggg ggtatttgaa
4501 tgggaagctt ttgcccgggg aaccaaagct ctcatggatg aggtggtgaa agccacttct
4561 aggggctgca tcaccatcat aggtaagcgg tcctatacaa agctaatacc catataagct
4621 ggcnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
4681 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnngcacact gccttacagt
4741 tttggtgcca atcccttttt tttcttttct ctcttttccc tttttacctg gctttcattc
4801 aacaggtggt ggagacactg ccacttgctg tgccaaatgg aacacggagg ataaagtcag
4861 ccatgtgagc actgggggtg gtgccagttt ggagctcctg gaaggtgagg gtcttctgtt
4921 ttttggcttg tttgggataa gggtggactg tgcagtgaga ggtgggtaga atggagtgga
4981 gaaagttaga aggtagtgtt gtcattagca gtcattacta cctgggcagt acagaggaac
5041 ttcagataaa gctcctggca tccactgagg cgggggaggg acagatagaa acttggtctg
5101 agagttatgg tnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
5161 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn ntatagtaat
5221 gctgtctatg tatgtgtgct ctctcaaaaa caggtaaagt ccttcctggg gtggatgctc
5281 tcagcaatat ttagtacttt cctgcctttt agttcctgtg cacagcccct aagtcaactt
5341 agcattttct gcatctccac ttggcattag ctaaaacctt ccatgtcaag attcagctag
5401 tggccaagag atgcagtgcc aggaaccctt aaacagttgc acagcatctc agctcatctt
5461 cactgcaccc tggatttgca tacattcttc aagatcccat ttgaattttt tagtgactaa
5521 accattgtgc attctagagt gcatatattt atattttgcc tgttaaaaag aaagtgagca
5581 gtgttagctt agttctcttt tgatgtaggt tattatgatt agctttgtca ctgtttcact
5641 actcagcatg gaaacaagat gaaattccat ttgtaggtag tgagacaaaa ttgatgatcc
5701 attaagtaaa caataaaagt gtccattgaa accgtgattt tttttttttt cctgtcatac
5761 tttgttagga agggtgagaa tagaatcttg aggaacggat cagatgtcta tattgctgaa
5821 tgcaagaagt ggggcagcag cagtggagag atgggacaat tagataaatg tccattcttt
5881 atcaagggcc tactttatgg cagacattgt gctagtgctt ttattctaac ttttattttt
5941 atcagttaca catgatcata atttaaaaag tcaaggctta taacaaaaaa gccccagccc
6001 attcctccca ttcaag
//