LOCUS AF520698 2166 bp mRNA linear HUM 29-JUL-2002
DEFINITION Homo sapiens scotin mRNA, complete cds.
ACCESSION AF520698
VERSION AF520698.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2166)
AUTHORS Bourdon,J.C., Renzing,J., Robertson,P.L., Fernandes,K.N. and
Lane,D.P.
TITLE Scotin, a novel p53-inducible proapoptotic protein located in the
ER and the nuclear membrane
JOURNAL J. Cell Biol. 158 (2), 235-246 (2002)
PUBMED 12135983
REFERENCE 2 (bases 1 to 2166)
AUTHORS Bourdon,J.C., Renzing,J. and Lane,D.P.
TITLE Direct Submission
JOURNAL Submitted (11-JUN-2002) Surgery & Molecular Oncology, University of
Dundee, Ninewells Hospital, Dundee DD1 9SY, UK
FEATURES Location/Qualifiers
source 1..2166
/db_xref="H-InvDB:HIT000081153"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="3"
/map="3p21.31"
CDS 135..857
/note="pro-apoptotic protein; located in the endoplasmic
reticulum and the nuclear membrane; contains a putative
transmembrane domain"
/codon_start=1
/product="scotin"
/protein_id="AAM74232.1"
/translation="MTAPVPAPRILLPLLLLLLLTPPPGARGEVCMASRGLSLFPESC
PDFCCGTCDDQYCCSDVLKKFVWSEERCAVPEASVPASVEPVEQLGSALRFRPGYNDP
MSGFGATLAVGLTIFVLSVVTIIICFTCSCCCLYKTCRRPRPVVTTTTSTTVVHAPYP
QPPSVPPSYPGPSYQGYHTMPPQPGMPAAPYPMQYPPPYPAQPMGPPAYHETLAGGAA
APYPASQPPYNPAYMDAPKAAL"
BASE COUNT 360 a 676 c 618 g 512 t
ORIGIN
1 cggacagagg ttccgggaac cagccgggcc ggggcggggc ggggcgaggg agaggggcgg
61 ccgcgcggat cactgaggct gtggcggcac tgcgcccggc gctcgcgtcc gtccgcccgt
121 ccgcccgccc agccatgact gcgccggtcc ccgcgccgcg gatcctgttg ccgttgctgt
181 tgctgctgct gctaacgccg cctccgggtg cacgtggtga ggtgtgtatg gcttcccgtg
241 gactcagcct cttccccgag tcctgtccag atttctgctg tggtacctgt gatgaccaat
301 actgctgctc tgacgtgctg aagaaatttg tgtggagcga ggaaaggtgt gctgtgcctg
361 aggccagcgt gcctgccagt gtagagccgg tggagcagct gggctcggcg ctgaggtttc
421 gccctggcta caacgacccc atgtcagggt tcggagcgac cttggccgtt ggcctgacca
481 tctttgtgct gtctgtcgtc actatcatca tctgcttcac ctgctcctgc tgctgccttt
541 acaagacgtg ccgccgacca cgtccggttg tcaccaccac cacatccacc actgtggtgc
601 atgcccctta tcctcagcct ccaagtgtgc cgcccagcta ccctggacca agctaccagg
661 gctaccacac catgccgcct cagccaggga tgccagcagc accctaccca atgcagtacc
721 caccacctta cccagcccag cccatgggcc caccggccta ccacgagacc ctggctggag
781 gagcagccgc gccctacccc gccagccagc ctccttacaa cccggcctac atggatgccc
841 cgaaggcggc cctctgagca ttccctggcc tctctggctg ccacttggtt atgttgtgtg
901 tgtgcgtgag tggtgtgcag gcgcggttcc ttacgcccca tgtgtgctgt gtgtgtccag
961 gcacggttcc ttacgcccca tgtgtgctgt gtgtgtcctg cctgtatatg tggcttcctc
1021 tgatgctgac aaggtgggga acaatccttg ccagagtggg ctgggaccag actttgttct
1081 cttcctcacc tgaaattatg cttcctaaaa tctcaagcca aactcaaaga atggggtggt
1141 ggggggcacc ctgtgaggtg gcccctgaga ggtgggggcc tctccagggc acatctggag
1201 ttcttctcca gcttacccta gggtgaccaa gtagggcctg tcacaccagg gtggcgcagc
1261 tttctgtgtg atgcagatgt gtcctggttt cggcagcgta gccagctgct gcttgaggcc
1321 atggctcgtc cccggagttg ggggtacccg ttgcagagcc agggacatga tgcaggcgaa
1381 gcttgggatc tggccaagtt ggactttgat cctttgggca gatgtcccat tgctccctgg
1441 agcctgtcat gcctgttggg gatcaggcag cctcctgatg ccagaacacc tcaggcagag
1501 ccctactcag ctgtacctgt ctgcctggac tgtcccctgt ccccgcatct cccctgggac
1561 cagctggagg gccacatgca cacacagcct agctgccccc agggagctct gctgcccttg
1621 ctggccctgc ccttcccaca ggtgagcagg gctcctgtcc accagcacac tcagttctct
1681 tccctgcagt gttttcattt tattttagcc aaacattttg cctgttttct gtttcaaaca
1741 tgatagttga tatgagactg aaacccctgg gttgtggagg gaaattggct cagagatgga
1801 caacctggca actgtgagtc cctgcttccc gacaccagcc tcatggaata tgcaacaact
1861 cctgtacccc agtccacggt gttctggcag cagggacacc tgggccaatg ggccatctgg
1921 accaaaggtg gggtgtgggg ccctggatgg cagctctggc ccagacatga atacctcgtg
1981 ttcctcctcc ctctattact gtttcaccag agctgtctta gctcaaatct gttgtgtttc
2041 tgagtctagg gtctgtacac ttgtttataa taaatgcaat cgtttggagc tgctgccccc
2101 tttcttcctg gcctcggctg ctggaattgg aatcaggctg tactctttcc atccatttgg
2161 gcttct
//