LOCUS AF487456 1880 bp mRNA linear HUM 23-JUL-2003
DEFINITION Homo sapiens pellino 3 alpha mRNA, complete cds.
ACCESSION AF487456
VERSION AF487456.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1880)
AUTHORS Jensen,L.E. and Whitehead,A.S.
TITLE Pellino3, a novel member of the Pellino protein family, promotes
activation of c-Jun and Elk-1 and may act as a scaffolding protein
JOURNAL J. Immunol. 171 (3), 1500-1506 (2003)
PUBMED 12874243
REFERENCE 2 (bases 1 to 1880)
AUTHORS Jensen,L.E.
TITLE Direct Submission
JOURNAL Submitted (25-FEB-2002) Department of Pharmacology, University of
Pennsylvania, School of Medicine, 156 Johnson Pavilion, 3620
Hamilton Walk, Philadelphia, PA 19104-6084, USA
FEATURES Location/Qualifiers
source 1..1880
/db_xref="H-InvDB:HIT000243597"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="HepG2"
CDS 1..1410
/note="signaling molecule"
/codon_start=1
/product="pellino 3 alpha"
/protein_id="AAO49465.1"
/translation="MVLEGNPEVGSPRTSDLQHRGNKGSCVLSSPGEDAQPGEEPIKY
GELIVLGCCEEGGEETEAQRGEVTGPRAHSCYNGCLASGDKGRRRSRLALSRRSHANG
VKPDVMHHISTPLVSKALSNRGQHSISYTLSRSHSVIVEYTHDSDTDMFQIGRSTENM
IDFVVTDTSPGGGAAEGPSAQSTISRYACRILCDRRPPYTARIYAAGFDASSNIFLGE
RAAKWRTPDGLMDGLTTNGVLVMHPAGGFSEDSAPGVWREISVCGNVYTLRDSRSAQQ
RGKLVENESNVLQDGSLIDLCGATLLWRTPAGLLRAPTLKQLEAQRQEANAARPQCPV
GLSTLAFPSPARGRTAPDKQQPWVYVRCGHVHGYHGWGCRRERGPQERECPLCRLVGP
YVPLWLGQEAGLCLDPGPPSHAFAPCGHVCSEKTARYWAQTPLPHGTHAFHAACPFCG
AWLTGEHGCVRLIFQGPLD"
regulatory 1837..1841
/regulatory_class="polyA_signal_sequence"
BASE COUNT 344 a 644 c 560 g 332 t
ORIGIN
1 atggtgctgg aaggaaaccc tgaagtgggg tccccccgaa cctcagacct ccagcaccgg
61 gggaacaagg gctcttgcgt tctctcctct cccggtgaag atgcgcagcc aggcgaggag
121 cccatcaagt atggtgaact catcgtcctg ggatgctgtg aggaaggagg tgaggaaacc
181 gaggctcaga gaggggaagt gactggccca agggcacaca gctgctacaa tggttgtctg
241 gcaagtgggg acaagggccg ccggcgaagc cgcctggcac tgagccgccg gtcgcacgcc
301 aacggggtga agccagacgt catgcaccac atctccacgc cgctcgtctc caaggcactg
361 agtaaccgtg gtcagcacag catctcgtat acactgtccc ggagccactc ggtcatagtg
421 gagtatacac atgatagcga cacagacatg ttccagattg gccgctccac agagaacatg
481 attgacttcg tggtaacaga cacgtcccct ggaggagggg ctgccgaggg cccttctgcc
541 cagagcacca tctcccgcta tgcctgccgc atcctctgtg accgccggcc accctatact
601 gcccgcatct atgccgctgg cttcgacgcc tctagcaaca tcttccttgg agagcgagcg
661 gccaaatggc ggaccccaga tggcctgatg gatggactga ccaccaatgg agtcctggtg
721 atgcacccgg caggcggctt ctccgaggac tcagccccgg gtgtctggcg ggagatctcg
781 gtctgtggga atgtgtacac attgcgggac agccgctcag cccagcagcg gggcaagctg
841 gtggaaaacg agtccaacgt gctgcaggac ggctctctca tcgacctgtg tggggccaca
901 ctgctgtggc gcacaccggc ggggctgctg cgggctccca cactgaagca actggaggcc
961 cagcggcagg aggcaaatgc agcgcggccc cagtgccccg tgggcctcag cactctggcc
1021 ttccccagcc cagcccgtgg ccgcacagcg cccgacaaac agcagccctg ggtctacgtc
1081 cgctgcgggc acgtccatgg ctaccacggc tggggctgcc ggcgggagcg gggcccccag
1141 gagcgcgaat gtcctctctg ccgccttgtg gggccttatg tgcctctatg gcttggccag
1201 gaggccggcc tctgcctgga ccctgggccg cctagccatg cctttgcacc ttgcggccac
1261 gtctgctctg agaagactgc ccgctactgg gcccagacac cactgcccca cggcacccat
1321 gctttccatg ccgcctgccc cttttgcggg gcctggctta ccggcgagca tggctgcgtc
1381 cgcctcattt tccagggccc gctggattag gctccctggg gccccctgct gctgtgccca
1441 cctgcccacc caggtcccca cctcctgcag cccagaggga gctctgcatg tgggacactc
1501 cctgctggca cagccacacc agatggacat gttggatggg ctgtgccctt ccccccaact
1561 gtggcccccc aaggaggtcc ccaagatctc caccccagtc atgctgatgg ggccttcagc
1621 accagctctg tcctgggtcg atggaggaaa gcccagcccc atggccttgc ccttcctggg
1681 gcatcccaca tcgtgccgcc gacactgtgt gcccctgggg gagtgaaggg gccaggggcc
1741 tttgaccccc agcttaggct ggctatgccc tgagcctgcc aacccagttt cagacactca
1801 tccttcatcc ttcctgctgc cgccctgggt tcctctataa acctcgctgc tcagctgccc
1861 ccacgaaaaa aaaaaaaaaa
//