LOCUS       AF307851                2521 bp    mRNA    linear   HUM 29-JAN-2001
DEFINITION  Homo sapiens p53 protein mRNA, complete cds.
ACCESSION   AF307851
VERSION     AF307851.1
KEYWORDS    .
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2521)
  AUTHORS   Chang,N.S., Pratt,N., Heath,J., Schultz,L., Sleve,D., Carey,G.B.
            and Zevotek,N.
  TITLE     Hyaluronidase induction of a WW domain-containing oxidoreductase
            that enhances tumor necrosis factor cytotoxicity
  JOURNAL   J. Biol. Chem. 276 (5), 3361-3370 (2001)
   PUBMED   11058590
REFERENCE   2  (bases 1 to 2521)
  AUTHORS   Chang,N.-S., Pratt,N. and Heath,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-SEP-2000) Laboratory of Molecular Immunology, Guthrie
            Research Institute, 1 Guthrie Square, Sayre, PA 18840, USA
FEATURES             Location/Qualifiers
     source          1..2521
                     /db_xref="H-InvDB:HIT000076904"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /clone="IMAGE:1847162"
     CDS             136..1317
                     /codon_start=1
                     /product="p53 protein"
                     /protein_id="AAG28785.1"
                     /db_xref="GI:11066970"
                     /translation="MEEPQSDPSVEPPLSQETFSDLWKLLPENNVLSPLPSQAMDDLM
                     LSPDDIEQWFTEDPGPDEAPRMPEAAPRVAPAPAAPTPAAPAPAPSWPLSSSVPSQKT
                     YQGSYGFRLGFLHSGTAKSVTCTYSPALNKMFCQLAKTCPVQLWVDSTPPPGTRVRAM
                     AIYKQSQHMTEVVRRCPHHERCSDSDGLAPPQHLIRVEGNLRVEYLDDRNTFRHSVVV
                     PYEPPEVGSDCTTIHYNYMCNSSCMGGMNRRPILTIITLEDSSGNLLGRNSFEVRVCA
                     CPGRDRRTEEENLRKKGEPHHELPPGSTKRALPNNTSSSPQPKKKPLDGEYFTLQIRG
                     RERFEMFRELNEALELKDAQAGKEPGGSRAHSSHLKSKKGQSTSRHKKLMFKTEGPDS
                     D"
BASE COUNT          544 a          719 c          623 g          635 t
ORIGIN      
        1 ggcacgagcc accgtccagg gagcaggtag ctgctgggct ccggggacac tttgcgttcg
       61 ggctgggagc gtgctttcca cgacggtgac acgcttccct ggattggcag ccagactgcc
      121 ttccgggtca ctgccatgga ggagccgcag tcagatccta gcgtcgagcc ccctctgagt
      181 caggaaacat tttcagacct atggaaacta cttcctgaaa acaacgttct gtcccccttg
      241 ccgtcccaag caatggatga tttgatgctg tccccggacg atattgaaca atggttcact
      301 gaagacccag gtccagatga agctcccaga atgccagagg ctgctccccg cgtggcccct
      361 gcaccagcag ctcctacacc ggcggcccct gcaccagccc cctcctggcc cctgtcatct
      421 tctgtccctt cccagaaaac ctaccagggc agctacggtt tccgtctggg cttcttgcat
      481 tctgggacag ccaagtctgt gacttgcacg tactcccctg ccctcaacaa gatgttttgc
      541 caactggcca agacctgccc tgtgcagctg tgggttgatt ccacaccccc gcccggcacc
      601 cgcgtccgcg ccatggccat ctacaagcag tcacagcaca tgacggaggt tgtgaggcgc
      661 tgcccccacc atgagcgctg ctcagatagc gatggtctgg cccctcctca gcatcttatc
      721 cgagtggaag gaaatttgcg tgtggagtat ttggatgaca gaaacacttt tcgacatagt
      781 gtggtggtgc cctatgagcc gcctgaggtt ggctctgact gtaccaccat ccactacaac
      841 tacatgtgta acagttcctg catgggcggc atgaaccgga ggcccatcct caccatcatc
      901 acactggaag actccagtgg taatctactg ggacggaaca gctttgaggt gcgtgtttgt
      961 gcctgtcctg ggagagaccg gcgcacagag gaagagaatc tccgcaagaa aggggagcct
     1021 caccacgagc tgcccccagg gagcactaag cgagcactgc ccaacaacac cagctcctct
     1081 ccccagccaa agaagaaacc actggatgga gaatatttca cccttcagat ccgtgggcgt
     1141 gagcgcttcg agatgttccg agagctgaat gaggccttgg aactcaagga tgcccaggct
     1201 gggaaggagc caggggggag cagggctcac tccagccacc tgaagtccaa aaagggtcag
     1261 tctacctccc gccataaaaa actcatgttc aagacagaag ggcctgactc agactgacat
     1321 tctccacttc ttgttcccca ctgacagcct cccaccccca tctctccctc ccctgccatt
     1381 ttgggttttg ggtctttgaa cccttgcttg caataggtgt gcgtcagaag cacccaggac
     1441 ttccatttgc tttgtcccgg ggctccactg aacaagttgg cctgcactgg tgttttgttg
     1501 tggggaggag gatggggagt aggacatacc agcttagatt ttaaggtttt tactgtgagg
     1561 gatgtttggg agatgtaaga aatgttcttg cagttaaggg ttagtttaca atcagccaca
     1621 ttctaggtag gggcccactt caccgtacta accagggaag ctgtccctca ctgttgaatt
     1681 ttctctaact tcaaggccca tatctgtgaa atgctggcat ttgcacctac ctcacagagt
     1741 gcattgtgag ggttaatgaa ataatgtaca tctggccttg aaaccacctt ttattacatg
     1801 gggtctagaa cttgaccccc ttgagggtgc ttgttccctc tccctgttgg tcggtgggtt
     1861 ggtagtttct acagttgggc agctggttag gtagagggag ttgtcaagtc tctgctggcc
     1921 cagccaaacc ctgtctgacc acctcttggt gaaccttagt acctaaaagg aaatctcacc
     1981 ccatcccaca ccctggagga tttcatctct tgtatatgat gatctggatc caccaagact
     2041 tgttttatgc tcagggtcaa tttctttttt cttttttttt ttttttttct ttttctttga
     2101 gactgggtct cgctttgttg cccaggctgg agtggagtgg cgtgatcttg gcttactgca
     2161 gcctttgcct ccccggctcg agcagtcctg cctcagcctc cggagtagct gggaccacag
     2221 gttcatgcca ccatggccag ccaacttttg catgttttgt agagatgggg tctcacagtg
     2281 ttgcccaggc tggtctcaaa ctcctgggct caggcgatcc acctgtctca gcctcccaga
     2341 gtgctgggat tacaattgtg agccaccacg tccagctgga agggtcaaca tcttttacat
     2401 tctgcaagca catctgcatt ttcaccccac ccttcccctc cttctccctt tttatatccc
     2461 atttttatat cgatctctta ttttacaata aaactttgct gccaaaaaaa aaaaaaaaaa
     2521 a
//