LOCUS AF185696 5084 bp mRNA linear HUM 21-MAY-2001
DEFINITION Homo sapiens oxysterol-binding protein 1 (OSBP1) mRNA, complete
cds.
ACCESSION AF185696
VERSION AF185696.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5084)
AUTHORS Moreira,E.F., Jaworski,C., Li,A. and Rodriguez,I.R.
TITLE Molecular and biochemical characterization of a novel
oxysterol-binding protein (OSBP2) highly expressed in retina
JOURNAL J. Biol. Chem. 276 (21), 18570-18578 (2001)
PUBMED 11278871
REFERENCE 2 (bases 1 to 5084)
AUTHORS Rodriguez,I.R.
TITLE Direct Submission
JOURNAL Submitted (13-SEP-1999) LRCMB, National Eye Institute, NIH, 6
Center Drive MSC 2740 6/304, Bethesda, MD 20892, USA
FEATURES Location/Qualifiers
source 1..5084
/db_xref="H-InvDB:HIT000072894"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..5084
/gene="OSBP1"
CDS 481..2904
/gene="OSBP1"
/codon_start=1
/product="oxysterol-binding protein 1"
/protein_id="AAG17011.1"
/translation="MAATELRGVVGPGPAAIAALGGGGAGPPVVGGGGGRGDAGPGSG
AASGTVVAAAAGGPGPGAGGVAAAGPAPAPPTGGSGGSGAGGSGSAREGWLFKWTNYI
KGYQRRWFVLSNGLLSYYRSKAEMRHTCRGTINLATANITVEDSCNFIISNGGAQTYH
LKASSEVERQRWVTALELAKAKAVKMLAESDESGDEESVSQTDKTELQNTLRTLSSKV
EDLSTCNDLIAKHGTALQRSLSELESLKLPAESNEKIKQVNERATLFRITSNAMINAC
RDFLMLAQTHSKKWQKSLQYERDQRIRLEETLEQLAKQHNHLERAFRGATVLPANTPG
NVGSGKDQCCSGKGDMSDEDDENEFFDAPEIITMPENLGHKRTGSNISGASSDISLDE
QYKHQLEETKKEKRTRIPYKPNYSLNLWSIMKNCIGKELSKIPMPVNFNEPLSMLQRL
TEDLEYHELLDRAAKCENSLEQLCYVAAFTVSSYSTTVFRTSKPFNPLLGETFELDRL
EENGYRSLCEQVSHHPPAAAHHAESKNGWTLRQEIKITSKFRGKYLSIMPLGTIHCIF
HATGHHYTWKKVTTTVHNIIVGKLWIDQSGEIDIVNHKTGDKCNLKFVPYSYFSRDVA
RKVTGEVTDPSGKVHFALLGTWDEKMECFKVQPVIGENGGDARQRGHEAEESRVMLWK
RNPLPKNAENMYYFSELALTLNAWESGTAPTDSRLRPDQRLMENGRWDEANAEKQRLE
EKQRLSRKKREAEAMKATEDGTPYDPYKALWFERKKDPVTKELTHIYRGEYWECKEKQ
DWSSCPDIF"
regulatory 5065..5070
/regulatory_class="polyA_signal_sequence"
/gene="OSBP1"
BASE COUNT 1324 a 1186 c 1315 g 1259 t
ORIGIN
1 agaagagcga tgggaggggg tgacgtggca gtgacaggcg cataaactga aatgaatggc
61 ggaaacagca gccaatcggc gatcagattg gccgggcatt ccgcattctc ccgtcctccc
121 tgagcgctgg aaacttcagg aaagcaccaa tgagcttccc caaaagtctg attggccttt
181 atctgaacca atcaaaggtg ggtctggcgg acgcgtccca ccccaggctc tcactgggcg
241 ctgtagaatg acaggcccga gagaaatgcc aatatccgcg gggtcttcct caagtgacac
301 tcagcggcac caatcgacgt ccttcttccc ggcggccgag ccctcctccc cgcggctggc
361 cgggcggggc ggggacgctg cgcggcggtg gctgatgcgg tagccgtgtg gggcgctccg
421 ggcggcgacg gcggctctcg taggcggttc cggtcttgta tctccaggcg gcggcggctc
481 atggcggcga cggagctgag aggagtggtg gggccaggcc cggcagccat tgcagcactt
541 ggcggcggcg gcgccggtcc cccagtggtg ggaggaggcg gcggccgcgg agatgcgggg
601 ccaggctccg gggccgcgtc agggacggtg gtcgcggcgg cggcgggagg cccgggcccg
661 ggggccgggg gagtggcggc ggctggcccg gcccctgcgc cgccgactgg gggctcgggc
721 ggctcgggcg ctgggggttc gggctcggct cgagagggct ggctcttcaa atggaccaat
781 tatatcaaag gctaccagcg gcgatggttc gtgctgagca acgggctcct gagctactac
841 agatcaaagg cagaaatgag acatacctgc cgtggtacca tcaacctcgc cacagccaac
901 atcaccgtgg aggactcctg caacttcatc atttccaatg ggggtgctca gacctaccat
961 ctgaaagcta gttcagaagt tgagcggcag cgctgggtga cggccctgga actggccaag
1021 gccaaagctg tgaagatgct ggcagagtca gatgaatcag gagatgaaga gtctgtctca
1081 caaactgaca agactgagct gcagaatacc cttcggaccc tctctagcaa agtagaggac
1141 ttgagcacgt gcaatgactt gatagctaag catggcacag ctctgcagcg ttctctcagt
1201 gagctggagt ccctgaagtt gcctgctgag agcaatgaaa agatcaaaca ggtcaacgaa
1261 cgagccacac tctttaggat aacatccaat gccatgatca acgcctgcag agatttcctc
1321 atgttagccc agacccatag taaaaaatgg caaaagtcac tacagtatga aagagaccag
1381 cgtatccgac tggaagaaac cctcgagcag ctggcgaagc agcataatca cctggagagg
1441 gccttccgag gagccacggt gctgccggca aacactcctg gcaatgtggg ttctggtaaa
1501 gatcagtgct gctctggcaa aggggacatg agcgatgaag atgatgagaa tgaatttttt
1561 gatgcacctg agatcatcac catgcctgaa aatttgggcc acaaacgtac tggcagcaat
1621 atcagtggag ccagcagtga catcagcctt gatgaacagt acaagcatca gctggaggag
1681 accaaaaagg aaaagagaac cagaatacca tacaagccaa actatagcct caatttatgg
1741 agcatcatga agaactgcat tggaaaagaa ctctctaaga tccccatgcc ggtaaacttt
1801 aatgagccct tgtccatgct tcagcgcctt actgaagatc tggaatacca tgagctgtta
1861 gaccgagctg caaaatgtga gaattctcta gaacagctct gttatgttgc agctttcacc
1921 gtgtcctcct actccactac tgtcttccgc accagtaagc cattcaaccc actgcttggg
1981 gagacctttg agctggaccg attagaggag aatgggtacc gatccctctg tgaacaggtg
2041 agtcatcatc cccctgctgc tgcgcaccat gctgagtcca aaaatggctg gacattgcgt
2101 caggaaatca aaatcaccag caagtttcga ggcaaatacc tctccattat gcccctcggt
2161 accattcatt gtattttcca tgcaactggg caccactaca cttggaagaa agttaccaca
2221 actgtacaca acattattgt gggcaagttg tggatagatc agtctggcga aattgatatt
2281 gtgaatcaca agacaggaga caagtgtaat cttaaatttg ttccttatag ctacttctct
2341 cgggatgtag caagaaaggt gacgggggaa gtgacagatc catcaggaaa agtccacttt
2401 gctcttctgg ggacgtggga tgagaaaatg gaatgtttca aagtacagcc agtcattggg
2461 gaaaatgggg gtgatgctcg acagagaggc catgaagcag aggaaagcag ggtcatgctg
2521 tggaaaagga atcctttacc gaagaatgca gaaaacatgt actacttctc agagcttgct
2581 ctgactctca atgcttggga aagtggcact gcccccacag acagccggtt acgacctgac
2641 cagagactga tggaaaatgg acgctgggat gaagcaaatg cggagaagca gcgcctggag
2701 gaaaaacaaa gactttccag aaagaagaga gaagcggaag ctatgaaagc cacagaggat
2761 ggcacaccat atgatcccta taaggcactg tggtttgagc ggaagaagga ccctgttacc
2821 aaggagttaa cccatattta taggggagaa tactgggagt gtaaagaaaa acaggactgg
2881 agctcatgcc cggacatttt ctgaaacggc agtaacaaaa aagaggagca tataatggag
2941 aagaggacag aggatgtgtg ggaaagctgg aagttgtgac tctcttacca agtgctttcc
3001 tcaagtttgt ctctcttgac caatcatttt ttccaaatca atcaccagaa ggagacacca
3061 gtggtggtga ttggctggtt gccttagctg attgaaactg aaatcgacat aggagatact
3121 atgtctgtaa gggagaggtt tagtggccga aggttagtgt tattccacat ccacgaagtc
3181 aagtattctt ggctcttctt tctccctctg cccccattta agacaatgtc actcaccctc
3241 cccttgtagt atcctgctca gccaagatct ggctaagatt atgattcagg ggcattttgg
3301 tgctgttaaa agcaagagcc gaatttagaa gttcccttaa aaagaaacac ataagactta
3361 ccaatggagg cattgtgaat ggttgcagtg gagcttaggt ataacatcat caagtgtgtt
3421 cacacgcgcg ggtcggttta atgggagtgt ccacgcggag ataactgcga tattggaaca
3481 cctgtgagag agattgttct atagggctgg aatattcaga gttacattct tggaagtttc
3541 tgtttttact tgcatcaaac acccctctgt tgttctccat catctttaat agcaactgga
3601 gaccactttg gtcattggta agggggtgca ttctcctcac aaaggggttt tatggacttc
3661 ctcaggcgga gagcttctga gaacacaggc aggatggaaa aagactacta gccacttttg
3721 ctttcccaac cccccttaat gccatccttc attgtctttc tggcttctct tcttctggca
3781 cagtaccatt ttgggtctgt gccccagtgt ggagcaaaac attgcctgtc ccattctgat
3841 atacttcaga atttgagagc agaagttaat gtggaacaaa agttttcacc atctctcaag
3901 ccccaaggac tggagccacc tctggaataa tgtgttaaat atctgtatat tatatatatg
3961 tagagaaaaa tctaattttt tggtttgatt tccttcccat taagaatctt gttttttgat
4021 acccttgtct ccctgagact ctttcttgga cacgtgttga tgtggatggc actcctgctc
4081 tccatctttt atgggcagag agatttcaaa acctgagcag gatcatgtct ggcagttact
4141 aaacagggac tttgtcatgg tttgtatcat ggggtgccta ctgctgtcta aactctgctc
4201 tcctaattag ctgactcttg aaaatgaaat cctaacctct ttcctgcctc ttttctttct
4261 cttttcagga agagtgtggg tagaaagtcc ggagggcaac ttccaattta attctgctct
4321 gtccggcgca taggctgaat tccaaaagaa ctttcttcct aggatgtggg gcttaaagca
4381 ccgtcatgtg gggtggatca gataattgct cctgtggggc cctggcttcc ttctctgttt
4441 gtgcagtatt tgtttttgtt gtcttgttga gaaatatccc ctgtgcaacc cacccttggt
4501 tgaggatcac aaattgaggt gccttccttg tatgcttttt gttagtattt tttgtttttg
4561 ttccttaact gctgagcctc agccagcgtg ggtcctgggg gaaataccat tccaaaggaa
4621 gccatcccta tggggaaatt ggttttactg ggtaaattaa tacttttatt tcttccccta
4681 tcccttcctt cctagttgtg ataaacatgg gagaggagtg actttgactg ctggggaatt
4741 tcctcctaag aaccttattc ccaaaataag ccagggatta tgtcaaggct tctttcaagg
4801 aggctcataa aagcagtgac ctcatccggg gctttggata gagtgagaat tccccaacta
4861 aattggactt ctctgcttta tccccttctc ttccttcacc atctgcacta catttctggc
4921 tgatcccaat cagattcccg ctaatggaag aagtttagaa tctttcaggt ggaataaagt
4981 cacatgaaaa caaaacacaa ctatatatat tttcagtttt tttgccttat tgattttttt
5041 ccaaaaaaaa aaaactacta aattaaataa ttttttaaaa gtca
//