LOCUS AF141968 17734 bp mRNA linear HUM 08-NOV-1999
DEFINITION Homo sapiens trabeculin-alpha mRNA, complete cds.
ACCESSION AF141968
VERSION AF141968.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 17734)
AUTHORS Sun,Y., Zhang,J., Kraeft,S.K., Auclair,D., Chang,M.S., Liu,Y.,
Sutherland,R., Salgia,R., Griffin,J.D., Ferland,L.H. and Chen,L.B.
TITLE Molecular cloning and characterization of human trabeculin-alpha, a
giant protein defining a new family of actin-binding proteins
JOURNAL J. Biol. Chem. 274 (47), 33522-33530 (1999)
PUBMED 10559237
REFERENCE 2 (bases 1 to 17734)
AUTHORS Sun,Y., Zhang,J., Auclair,D. and Chen,L.B.
TITLE Direct Submission
JOURNAL Submitted (10-APR-1999) Cancer Biology, Dana-Farber Cancer
Institute, 44 Binney, Boston, MA 02115, USA
FEATURES Location/Qualifiers
source 1..17734
/db_xref="H-InvDB:HIT000071191"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="1"
/map="1p33-p34.2"
CDS 965..17086
/note="cytoskeletal giant protein; actin-binding protein"
/codon_start=1
/product="trabeculin-alpha"
/protein_id="AAF06360.1"
/translation="MFPVLWAGIPGRDVGSLQPLPPGFKQFCTSASRVAVIADERDRV
QKKTFTKWVNKHLMKVRKHINDLYEDLRDGHNLISLLEVLSGIKLPREKGRMRFHRLQ
NVQIALDFLKQRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIYISGESGDMS
AKEKLLLWTQKVTAGYTGIKCTNFSSCWSDGKMFNALIHRYRPDLVDMERVQIQSNRE
NLEQAFEVAERLGVTRLLDAEDVDVPSPDEKSVITYVSSIYDAFPKVPEGGEGISATE
VDSRWQEYQSRVDSLIPWIKQHTILMSDKTFPQNPVELKALYNQYIHFKETEILAKER
EKGRIEELYKLLEVWIEFGRIKLPQGYHPNDVEEEWGKLIIEMLEREKSLRPAVERLE
LLLQIANKIQNGALNCEEKLTLAKNTLQADAAHLESGQPVQCESDVIMYIQECEGLIR
QLQVDLQILRDENYYQLEELAFRVMRLQDELVTLRLECTNLYRKGHFTSLELVPPSTL
TTTHLKAEPLTKATHSSSTSWFRKPMTRAELVAISSSEDEGNLRFVYELLSWVEEMQM
KLERAEWGNDLPSVELQLETQQHIHTSVEELGSSVKEARLYEGKMSQNFHTSYAETLG
KLETQYCKLKETSSFRMRHLQSLHKFVSRATAELIWLNEKEEEELAYDWSDNNSNISA
KRNYFSELTMELEEKQDVFRSLQDTAELLSLENHPAKQTVEAYSAAVQSQLQWMKQLC
LCVEQHVKENTAYFQFFSDARELESFLRNLQDSIKRKYSCDHNTSLSRLEDLLQDSMD
EKEQLIQSKSSVASLVGRSKTIVQLKPRSPDHVLKNTISVKAVCDYRQIEITICKNDE
CVLEDNSQRTKWKVISPTGNEAMVPSVCFLIPPPNKDAIEMASRVEQSYQKVMALWHQ
LHVNTKSLISWNYLRKDLDLVQTWNLEKLRSSAPGECHQIMKNLQAHYEDFLQDSRDS
VLFSVADRLRLEEEVEACKARFQHLMKSMENEDKEETVAKMYISELKNIRLRLEEYEQ
RVVKRIQSLASSRTDRDAWQDNALRIAEQEHTQEDLQQLRSDLDAVSMKCDSFLHQSP
SSSSVPTLRSELNLLVEKMDHVYGLSTVYLNKLKTVDVIVRSIQDAELLVKGYEIKLS
QEEVVLADLSALEAHWSTLRHWLSDVKDKNSVFSVLDEEIAKAKVVAEQMSRLTPERN
LDLERYQEKGSQLQERWHRVIAQLEIRQSELESIQEVLGDYRACHGTLIKWIEETTAQ
QEMMKPGQAEDSRVLSEQLSQQTALFAEIERNQTKLDQCQKFSQQYSTIVKDYELQLM
TYKAFVESQQKSPGKRRRMLSSSDAITQEFMDLRTRYTALVTLTTQHVKYISDALRRL
EEEEKVVEEEKQEHVEKVKELLGWVSTLARNTQGKATSSETKESTDIEKAILEQQVLS
EELTTKKEQVSEAIKTSQIFLAKHGHKLSEKEKKQISEQLNALNKAYHDLCDGSANQL
QQLQSQLAHQTEQKTLQKQQNTCHQQLEDLCSWVGQAERALAGHQGRTTQQDLSALQK
NQSDLKDLQDDIQNRATSFATVVKDIEGFMEENQTKLSPRELTALREKLHQAKEQYEA
LQEETRVAQKELEEAVTSALQQETEKSKAAKELAENKKKIDALLDWVTSVGSSGGQLL
TNLPGMEQLSGASLEKGALDTTDGYMGVNQAPEKLDKQCEMMKARHQELLSQQQNFIL
ATQSAQAFLDQHGHNLTPEEQQMLQQKLGELKEQYSTSLAQSEAELKQVQTLQDELQK
FLQDHKEFESWLERSEKELENMHKGGSSPETLPSLLKRQGSFSEDVISHKGDLRFVTI
SGQKVLDMENSFKEGKEPSEIGNLVKDKLKDATERYTALHSKCTRLGSHLNMLLGQYH
QFQNSADSLQAWMQACEANVEKLLSDTVASDPGVLQEQLATTKQLQEELAEHQVPVEK
LQKVARDIMEIEGEPAPDHRHVQETTDSILSHFQSLSYSLAERSSLLQKAIAQSQSVQ
ESLESLLQSIGEVEQNLEGKQVSSLSSGVIQKALATNMKLKQDIARQKSSLEATREMV
TRFMETADSTTAAVLQGKLAEVSQRFEQLCLQQQEKESSLKKLLPQAEMFEHLSGKLQ
QFMENKSRMLASGNQPDQDITHFFQQIQELNLEMEDQQENLDTLEHLVTELSSCGFAL
DLCQHQDRVQNLRKDFTELQKTVKEREKDASSCQEQLDEFRKLVRTFQKWLKETEGSI
PPTETSVSAKELEKQIEHLKSLLDDWASKGTLVEEINCKGTSLENLIMEITAPDSQGK
TDLTEIQCDMSDVNLKYEKLGGVLHERQESLQAILNRMEEVHKEANSVLQWLESKEEV
LKSMDAMSSPTKTETVKAQAESNKAFLAELEQNSPKIQKVKEALAGLLVTYPNSQEAE
NWKKIQEELNSRWERATEVTVARQRQLEESASHLACFQAAESQLRPWLMEKELMMGVL
GPLSIDPNMLNAQKQQVQFMLKEFEARRQQHEQLNEAAQGILTGPGDVSLSTSQVQKE
LQSINQKWVELTDKLNSRSSQIDQAIVKSTQYQELLQDLSEKVRAVGQRLSVQSAIST
QPEAVKQQLEETSEIRSDLEQLDHEVKEAQTLCDELSVLIGEQYLKDELKKRLETVAL
PLQGLEDLAADRINRLQAALASTQQFQQMFDELRTWLDDKQSQQAKNCPISAKLERLQ
SQLQENEEFQKSLNQHSGSYEVIVAEGESLLLSVPPGEEKRTLQNQLVELKNHWEELS
KKTADRQSRLKDCMQKAQKYQWHVEDLVPWIEDCKAKMSELRVTLDPVQLESSLLRSK
AMLNEVEKRRSLLEILNSAADILINSSEADEDGIRDEKAGINQNMDAVTEELQAKTGS
LEEMTQRLREFQESFKNIEKKVEGAKHQLEIFDALGSQACSNKNLEKLRAQQEVLQAL
EPQVDYLRNFTQGLVEDAPDGSDASQLLHQAEVAQQEFLEVKQRVNSGCVMMENKLEG
IGQFHCRVREMFSQLADLDDELDGMGAIGRDTDSLQSQIEDVRLFLNKIHVLKLDIEA
SEAECRHMLEEEGTLDLLGLKRELEALNKQCGKLTERGKARQEQLELTLGRVEDFYRK
LKGLNDATTAAEEAEALQWVVGTEVEIINQQLADFKMFQKEQVDPLQMKLQQVNGLGQ
GLIQSAGKDCDVQGLEHDMEEINARWNTLNKKVAQRIAQLQEALLHCGKFQDALEPLL
SWLADTEELIANQKPPSAEYKVVKAQIQEQKLLQRLLDDRKATVDMLQAEGGRIAQSA
ELADREKITGQLESLESRWTELLSKAAARQKQLEDILVLAKQFHETAEPISDFLSVTE
KKLANSEPVGTQTAKIQQQIIRHKALEEDIENHATDVHQAVKIGQSLSSLTSPAEQGV
LSEKIDSLQARYSEIQDRCCRKAALLDQALSNARLFGEDEVEVLNWLAEVEDKLSSVF
VKDFKQDVLHRQHADHLALNEEIVNRKKNVDQAIKNGQALLKQTTGEEVLLIQEKLDG
IKTRYADITVTSSKALRTLEQARQLATKFQSTYEELTGWLREVEEELATSGGQSPTGE
QIPQFQQRQKELKKEVMEHRLVLDTVNEVSRALLELVPWRAREGLDKLVSDANEQYKL
VSDTIGQRVDEIDAAIQRSQQYEQAADAELAWVAETKRKLMALGPIRLEQDQTTAQLQ
VQKAFSIDIIRHKDSMDELFSHRSEIFGTCGEEQKTVLQEKTESLIQQYEAISLLNSE
RYARLERAQVLVNQFWETYEELSPWIEETRALIAQLPSPAIDHEQLRQQQEEMRQLRE
SIAEHKPHIDKLLKIGPQLKELNPEEGEMVEEKYQKAENMYAQIKEEVRQRALALDEA
VSQSTQITEFHDKIEPMLETLENLSSRLRMPPLIPAEVDKIRECISDNKSATVELEKL
QPSFEALKRRGEELIGRSQGADKDLAAKEIQDKLDQMVFFWEDIKARAEEREIKFLDV
LELAEKFWYDMAALLTTIKDTQDIVHDLESPGIDPSIIKQQVEAAETIKEETDGLHEE
LEFIRILGADLIFACGETEKPEVRKSIDEMNNAWENLNKTWKERLEKLEDAMQAAVQY
QDTLQAMFDWLDNTVIKLCTMPPVGTDLNTVKDQLNEMKEFKVEVYQQQIEMEKLNHQ
GELMLKKATDETDRDIIREPLTELKHLWENLGEKIAHRQHKLEGALLALGQFQHALEE
LMSWLTHTEELLDAQRPISGDPKVIEVELAKHHVLKNDVLAHQATVETVNKAGNELLE
SSAGDDASSLRSRLEAMNQCWESVLQKTEEREQQLQSTLQQAQGFHSEIEDFLLELTR
MESQLSASKPTGGLPETAREQLDTHMELYSQLKAKEETYNQLLDKGRLMLLSRDDSGS
GSKTEQSVALLEQKWHVVSSKMEERKSKLEEALNLATEFQNSLQEFINWLTLAEQSLN
IASPPSLILNTVLSQIEEHKVFANEVNAHRDQIIELDQTGNQLKFLSQKQDVVLIKNL
LVSVQSRWEKVVQRSIERGRSLDDARKRAKQFHEAWKKLIDWLEDAESHLDSELEISN
DPDKIKLQLSKHKEFQKTLGGKQPVYDTTIRTGRALKEKTLLPEDTQKLDNFLGEVRD
KWDTVCGKSVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLAEDQPVHGDLDLVM
NLMDAHKVFQKELGKRTGTVQVLKRSGRELIENSRDDTTWVKGQLQELSTRWDTVCKL
SVSKQSRLEQALKQAEVFRDTVHMLLEWLSEAEQLRFRGALPDDTEALQSLIDTHKEF
MKKVEEKRVDVNSAVAMGEVILAVCHPDCITTIKHWITIIRARFEEVLTWAKQHQQRL
ETALSELVANAELLEELLAWIQWAETTLIQRDQEPIPQNIDRVKALIAEHQTFMEEMT
RKQPDVDRVTKTYKRKNIEPTHAPFIEKSRSGGRKSLSQPTPPPMPILSQSEAKNPRI
NQLSARWQQVWLLALERQRKLNDALDRLEELKEFANFDFDVWRKKYMRWMNHKKSRVM
DFFRRIDKDQDGKITRQEFIDGILASKFPTTKLEMTAVADIFDRDGDGYIDYYEFVAA
LHPNKDAYRPTTDADKIEDEVTRQVAQCKCAKRFQVEQIGENKYRFGDSQQLRLVRIL
RSTVMVRVGGGWMALDEFLVKNDPCRARGRTNIELREKFILPEGASQGMTPFRSRGRR
SKPSSRAASPTRSSSSASQSNHSCTSMPSSPATPASGTKVIPSSGSKLKRPTPTFHSS
RTSLAGDTSNSSSPASTGAKTNRADPKKSASRPGSRAGSRAGSRASSRRGSDASDFDL
LETQSACSDTSESSAAGGQGNSRRGLNKPSKIPTMSKKTTTASPRTPGPKR"
BASE COUNT 5434 a 3879 c 4506 g 3915 t
ORIGIN
1 tcaaaacacc atctattaaa gctgacaatt gtcacaagca gaattgaata ctcaaaggga
61 agttaacttc acacagaaaa acacttcata tttcattcaa cttgcaacgt atttactgag
121 cgtctaccgt gtgtaaggca gcctgctagg aaatggggta cgaccctcct cctcacagag
181 cttacattct gacaggggaa cccgaagtga acaagcatga tctgcaacag gtatgagatg
241 tcaagaaagc ctattacaga ggcacccagg cccagtctac ggggtcacta aaggctatgg
301 gataaactga tctgaaggat gagcacaaat caatcatcga gaggctgaga gcagctcaag
361 tcgggggaat aagatgtgcg agaagcagga gagagcagga tgaaataaaa tcaggcccgt
421 gtgatgcgtg gtgaacagtg agtacccaga gaagcgaagc tgggggctga ggggctggtc
481 aggaacacgg gcttaattca tcaacccaac agcaaacatc agtgcaacaa tgtaagcaca
541 tttaccttct gggtcataat gtaatttctt ccaaagccag tggtggcact cagatatttg
601 atcagaggat tgacagattc aggcttttgg tggaaaagcc atacctggaa aggaaggatg
661 tgtcaatgat ttgtttcttc tgcccaaggt gagtgaggct ggtggagagt cactatctgc
721 actttataga gctccccaga caaattataa acatcctctc aaatatcatc agtgaatggt
781 ttggcaaata tattgagaac caattaaaat atagtttaaa agcacttgct tctacaacca
841 atttgtattc ccacaataaa tgtatttatt tctgtaacac ttaccaaaac aagagcatca
901 aagccaattc cttcacactg ccctccctcc cacctgctct tcatgaggag tcctttattc
961 ctgcatgttt cctgttcttt gggccggaat tccggggcgc gatgtcggct cactacaacc
1021 tctgcctcct ggattcaagc aattctgtac ctcagcctcc cgagtggctg tgattgcaga
1081 tgaacgggac cgggttcaga agaaaacgtt caccaagtgg gtcaacaagc acttaatgaa
1141 ggtccgcaag cacatcaatg atctttatga agatctgcgg gatggccata acctgatctc
1201 tctgttggag gtcctctcag gcatcaaact gccccgggag aagggcagga tgcgttttca
1261 taggctgcag aatgtgcaga ttgccctgga cttcctaaag cagcgacagg tgaaactagt
1321 gaatattcgc aatgatgaca tcacagatgg caaccccaag ttgaccctgg gtctgatctg
1381 gaccattatt ttgcatttcc agatctctga catctacatt agtggagaat caggggatat
1441 gtcagccaag gagaaactac tcctgtggac ccagaaggtg acagctggtt acacaggaat
1501 caaatgcacc aacttttcct cctgctggag tgatgggaag atgttcaatg cactcattca
1561 ccgataccga cccgatctag tagacatgga gagggtgcaa atccaaagta accgagagaa
1621 tctggaacaa gcttttgaag tggcagaaag actgggggtc actcgcctgc tggatgcaga
1681 agatgtggat gtgccatctc cagatgaaaa gtctgtaatc acttatgtgt cttcgattta
1741 tgatgccttc cctaaagttc ctgagggtgg agaagggatc agtgctacgg aagtggactc
1801 caggtggcaa gaataccaaa gccgagtgga ctccctcatt ccctggatca aacagcatac
1861 aatactgatg tcagataaaa cttttcccca aaaccctgtt gaactaaagg cactttataa
1921 ccaatatata cacttcaaag aaacagaaat tctggccaag gagagagaaa aaggaagaat
1981 tgaggaatta tataaattac tagaggtgtg gattgaattt ggccgaatta aactgcctca
2041 aggttatcac cctaatgatg tggaagaaga gtggggaaag ctcatcatag agatgctgga
2101 acgagagaaa tcacttcggc cggctgtgga gaggctggaa ttgctgctac agattgcaaa
2161 caaaatccag aatggtgctt tgaactgtga agaaaaactg acactagcta agaatacact
2221 gcaggctgat gctgctcacc tggaatcagg acaaccggta caatgtgagt cagatgtcat
2281 tatgtacatt caggagtgtg aaggtctcat caggcagctg caggtggatc tccagatcct
2341 gcgggatgag aattactacc agctagaaga gctggctttt agggtcatgc gtcttcagga
2401 tgagctggtc accttgcgtc tagagtgtac aaacctgtac cggaagggtc atttcacttc
2461 acttgaattg gttccaccct ctactttaac caccactcat ctgaaagcag aacccttaac
2521 caaggcaacc cattcttctt ctacctcctg gttccgaaag cctatgactc gggctgaact
2581 tgtggccatc agctcctctg aagatgaagg caatctccga tttgtgtatg aactactgtc
2641 ttgggtagaa gagatgcaga tgaaactgga gcgagcagag tggggcaatg acctgcctag
2701 tgtggagttg cagctagaaa cacagcagca catccatacg agtgtagaag agctgggctc
2761 aagtgtcaag gaggccaggt tgtatgaggg aaagatgtcc cagaatttcc ataccagcta
2821 tgctgaaact cttggaaagc tggagacaca gtattgtaaa ttgaaggaaa cttctagctt
2881 ccggatgagg caccttcaga gcctgcataa atttgtttcc agagctacag ctgagttgat
2941 ctggttgaat gagaaggagg aggaggaact agcatatgac tggagtgaca acaattccaa
3001 tatctcagcc aagagaaatt acttctctga gttgacaatg gaactggagg agaaacagga
3061 tgtgtttcgt tctctacaag atacagcaga actactttca cttgagaacc acccagccaa
3121 gcagacagtg gaggcttaca gtgctgctgt ccagtcccag ttgcagtgga tgaagcagct
3181 gtgcctgtgt gttgagcagc atgtgaaaga gaatactgct tattttcagt tcttcagtga
3241 tgcacgagag ctggagtcat tcttgaggaa cctccaagat tccattaaac gaaaatattc
3301 ctgtgaccac aacaccagct tatcccgcct tgaagacctg ctccaggact ccatggatga
3361 aaaggagcag cttatacagt ccaagagttc cgttgccagt ctcgttggga gatcaaaaac
3421 catcgttcag ctaaaaccac gcagtccaga ccatgtgtta aagaacacca tttctgtcaa
3481 ggctgtctgt gactacaggc agatcgagat tactatttgc aaaaatgatg aatgtgtgct
3541 agaagataat tctcagcgga ccaaatggaa agtgatcagc cccacaggga acgaggcaat
3601 ggtgccgtca gtctgcttcc tcatcccccc acccaataag gatgccattg agatggccag
3661 cagggtcgaa caatcttatc agaaggttat ggccctttgg catcagctgc atgttaacac
3721 caaaagcctt atctcttgga actatctgcg taaagacctt gaccttgtac agacctggaa
3781 cctagaaaag cttcgatcct cagcaccagg ggagtgccat cagattatga agaaccttca
3841 ggcccactat gaagactttc tgcaggatag tcgtgactct gtgctgttct cagtggctga
3901 tcgcttgcgc ttggaagagg aggtggaagc ttgtaaagcc cgcttccagc acctgatgaa
3961 gtccatggag aatgaggaca aagaggagac tgtggccaag atgtacattt cagagttgaa
4021 gaacatccgg ctacgcctgg aggagtatga acagagggtg gtcaaacgaa ttcagtctct
4081 agccagctct aggactgaca gagatgcctg gcaggacaat gcattaagga ttgcagagca
4141 agagcacacc caggaggatt tacagcaatt gaggtcagac ttggatgcag tttctatgaa
4201 atgtgacagc tttctccatc agtctccatc tagttcaagt gtcccaactc tgcgctcaga
4261 actgaatctg ctggtggaga agatggacca tgtctatggt ctctctactg tatatctgaa
4321 taagttaaag acagttgatg ttatagtacg tagcatacag gatgctgaac tcttggtcaa
4381 aggttatgag attaagctga gtcaagaaga agtagtactg gcagatctct cagctctgga
4441 ggcccattgg tcgacattac ggcactggct tagtgatgtg aaggacaaga attcagtgtt
4501 ttcagtcctg gatgaggaaa ttgccaaggc caaggtagtg gcagagcaga tgagtcgtct
4561 gacaccagag cgaaatctgg atttggagcg ctatcaggaa aaaggctccc agctgcagga
4621 gcgttggcac cgagtcattg cccagctcga gattcgccaa tctgagctag aaagtatcca
4681 ggaagttctg ggagattacc gagcctgcca tggaactctc atcaagtgga ttgaggaaac
4741 cactgcccag caggaaatga tgaagccagg ccaggcagag gatagcagag tgctttcgga
4801 gcagctcagc cagcagacgg ccctatttgc agaaattgag agaaatcaga caaaactgga
4861 tcaatgtcaa aaattttccc agcagtactc tactattgta aaggactatg aattgcaact
4921 gatgacatac aaggcctttg tggaatcgca gcagaaatcc cctggcaagc gccgtcgcat
4981 gctttcctct tcagatgcca tcactcaaga gttcatggac ttaaggactc gctacacggc
5041 attggtgact ttaacaactc agcacgtgaa atacatcagt gatgcactcc ggcgtctgga
5101 ggaggaggag aaagtggtag aagaggagaa acaagaacat gtggagaagg ttaaagaact
5161 tttgggctgg gtgtctaccc tagcgaggaa tacacaagga aaagctacct catccgagac
5221 caaagaatca acagacattg aaaaagctat tttggaacag caggttctgt cagaagagct
5281 gacaacaaag aaagaacaag tctctgaagc tattaaaaca tcacagatct tcttggccaa
5341 gcatggtcat aagctctcag aaaaagagaa gaaacaaata tctgagcaat tgaatgccct
5401 aaacaaggct taccatgacc tttgtgatgg ttctgcaaat cagcttcagc agcttcagag
5461 ccagttggct caccagacag aacaaaagac cctgcagaaa caacaaaata cctgtcacca
5521 gcaactggag gatctttgca gttgggtagg acaggcagaa agagcactgg caggccacca
5581 aggcagaacc acccagcagg atctctctgc tttgcagaag aaccaaagtg acttgaagga
5641 tttacaggat gacattcaga atcgtgccac ctcatttgcc actgttgtca aggacattga
5701 ggggttcatg gaagagaatc agaccaagct gagcccacgt gagttgacag ctcttcggga
5761 aaagcttcat caggctaagg agcaatatga ggcgctccag gaagagacac gtgtggccca
5821 gaaggaactg gaggaagcag tgacctccgc cttacagcag gagactgaaa agagtaaagc
5881 agcaaaggaa ctggcagaga acaagaagaa gatcgatgct ctcctggatt gggtaacttc
5941 agtaggatca tctggtggac agctgctgac caaccttcca ggaatggagc agctctcggg
6001 agctagcttg gagaaaggag ccttggacac cactgatggt tacatggggg tgaatcaagc
6061 cccagagaaa ctggacaagc aatgtgagat gatgaaggcc cgtcaccaag aattgctgtc
6121 ccagcagcaa aatttcattc tggccaccca gtcagctcag gccttcttgg atcagcatgg
6181 ccacaatctc acacctgagg agcaacagat gctgcaacag aagctgggag agctaaagga
6241 acaatactct acttccctgg cccaatcaga ggcagaactg aagcaggtgc agacacttca
6301 ggatgagttg cagaaatttc tgcaggatca taaagagttt gaaagctggt tggaacgatc
6361 cgagaaagag ctggagaaca tgcataaggg aggcagcagc cccgagaccc ttccctccct
6421 gctaaagcgg caaggaagct tctcagagga tgtcatttcc cacaaaggag acttgagatt
6481 tgtgactatc tcaggacaga aagtcttgga catggaaaac agttttaagg aaggcaaaga
6541 accatcagaa attggaaact tagtaaagga caagttgaag gatgcaacag aaagatacac
6601 tgctctccac tcaaagtgta cacgattagg atctcacctg aatatgctgt taggccagta
6661 tcatcaattc caaaacagtg ctgacagcct gcaggcctgg atgcaggctt gtgaggccaa
6721 cgtggagaag ctcctctcag atactgttgc ctctgaccct ggagttctcc aggagcagct
6781 tgcaacaaca aagcagttgc aggaggaatt ggctgagcac caagtacctg tggaaaaact
6841 ccaaaaagta gctcgtgaca taatggaaat tgaaggggag ccagccccag accacaggca
6901 tgttcaagaa actacagatt ccatactcag ccacttccaa agcctctcct atagcctggc
6961 tgagcgatct tctctgctgc agaaagcaat tgcccaatct cagagtgtcc aggaaagcct
7021 ggagagcctg ttgcagtcta ttggggaagt tgaacaaaac ctggaaggga agcaggtgtc
7081 atcactctca tcaggagtca tccagaaagc cttagccaca aatatgaaat tgaagcagga
7141 cattgctcgg caaaagagca gcttggaggc cacccgtgag atggtgaccc gattcatgga
7201 gacagcagac agtactacag cagcagtgct gcagggcaaa ctggcagagg tgagccagcg
7261 gttcgaacag ctctgtctac agcagcaaga aaaggagagc tccctaaaga agcttctacc
7321 ccaggcagag atgtttgaac acctctctgg taagctgcag cagttcatgg aaaacaaaag
7381 tcggatgctg gcctctggaa atcagccaga tcaagatatt acacatttct tccaacagat
7441 ccaggagctc aatttggaaa tggaagacca acaggagaac ctagatactc ttgagcacct
7501 ggtcactgaa ctgagctctt gtggctttgc gctggacttg tgccagcatc aggacagggt
7561 acagaatcta agaaaagact tcacagagct acagaagaca gttaaagaga gagagaaaga
7621 tgcatcatct tgccaggaac agttggatga attccggaag ctggtcagga ccttccagaa
7681 atggttgaaa gaaactgaag ggagtattcc acctacggaa acttctgtga gtgctaaaga
7741 gttagaaaag cagattgaac acctgaagag tctactagat gactgggcaa gtaagggaac
7801 tctggtggaa gaaatcaatt gcaaaggtac ttctttagaa aatctcatca tggaaatcac
7861 agcacctgat tcccaaggca agacagatct gacggagatc cagtgtgaca tgtcagatgt
7921 aaacttgaag tatgagaaac tagggggagt actccatgaa cgccaggaaa gccttcaggc
7981 tatcctcaac agaatggagg aggtccacaa ggaggcaaac tctgtgctgc agtggctgga
8041 atcaaaagag gaagtcctga aatccatgga tgccatgtca tctccaacca agacagaaac
8101 agtgaaagcc caagctgaat ctaacaaggc cttcctggct gagttggaac agaattctcc
8161 aaaaattcaa aaagtaaagg aagccctggc tggattactg gtgacatatc ccaactcaca
8221 ggaagcagaa aattggaaga aaattcagga agaactcaat tcccgatggg aaagggccac
8281 tgaggttact gtggctcggc aaaggcagct agaggaatct gcaagtcatc tggcctgctt
8341 ccaggctgca gaatcccagc tccggccgtg gctgatggag aaagaactga tgatgggagt
8401 gctggggccc ctgtctattg accccaacat gttgaatgca caaaagcaac aggtccagtt
8461 tatgctaaag gaatttgaag cacgcaggca acagcatgag caactgaatg aggcagctca
8521 gggcatccta acaggccctg gagatgtctc tctgtccacc agccaagtac agaaagaact
8581 ccagagcatc aatcagaaat gggttgagct gactgacaaa ctcaactccc gttccagcca
8641 aattgaccaa gctattgtta agagcaccca gtaccaggaa ctgctccagg acttatcaga
8701 gaaggtgagg gcagttggac aacggctgag tgtccagtca gctatcagca cccaaccaga
8761 ggctgtaaag cagcaattgg aagagaccag tgaaattcga tctgacttgg agcagttaga
8821 ccacgaggtt aaggaggctc agacactgtg cgatgaactc tcagtgctca ttggtgagca
8881 gtacctcaag gatgaactga agaagcgttt ggagacagtt gccctgcctc tccaaggttt
8941 agaagacctt gcagccgatc gcattaacag actccaggca gctcttgcca gcacccagca
9001 gttccagcaa atgtttgatg agttgaggac ctggttggat gataaacaaa gccagcaagc
9061 aaaaaactgc ccaatttctg caaaattgga gcggctacag tctcagctac aggagaatga
9121 agagtttcag aaaagtctta atcaacacag tggctcctat gaggtgattg tggctgaagg
9181 ggaatctcta cttctttctg tacctcctgg agaagagaaa aggactctac aaaaccagtt
9241 ggttgagctc aaaaaccatt gggaagagct tagtaaaaaa actgcagaca gacaatccag
9301 gctcaaggat tgtatgcaga aagctcagaa atatcagtgg catgtggaag accttgtgcc
9361 atggatagaa gattgtaaag ctaagatgtc tgagttgcga gtcactctgg atccagtgca
9421 gctagagtcc agtctcctaa gatcaaaggc tatgctgaat gaggtggaga agcgccgctc
9481 cctgctggaa atattgaata gtgctgctga cattctgatc aattcttcag aagcagatga
9541 ggatggaatc cgggatgaga aggctgggat caaccagaac atggatgctg ttacagaaga
9601 gctgcaggcc aaaacagggt cactcgaaga aatgactcag aggctcaggg agttccagga
9661 aagctttaag aatattgaaa agaaggttga aggagccaaa caccaacttg agatctttga
9721 tgctctgggt tctcaagcct gtagcaacaa gaacctggag aagctaagag ctcaacagga
9781 agtgctgcag gccctagagc ctcaggtaga ctatctgagg aactttactc agggtctggt
9841 agaagatgcc ccagatggat ctgatgcttc tcaacttctc caccaagctg aggtcgccca
9901 gcaagagttc ctcgaagtta agcaaagagt gaacagtggt tgtgtgatga tggaaaacaa
9961 gctggagggg attggccagt ttcactgccg ggtccgagag atgttctctc aattggcaga
10021 cctggatgat gagctagatg gcatgggtgc tattggcaga gacactgata gcctccagtc
10081 ccaaatcgag gatgtccggc tattccttaa caaaattcac gtcctcaaat tagacataga
10141 ggcctctgaa gcagagtgtc gacatatgct agaagaagag gggactctgg atttgttagg
10201 tctcaaaagg gagctagaag ccctgaacaa acagtgtggc aaactgacag agagggggaa
10261 agctcgtcag gaacagctgg aactgacact aggccgtgta gaggacttct acaggaaatt
10321 gaaaggactc aatgacgcga ccacagcagc agaggaggca gaggccctcc agtgggtagt
10381 ggggaccgaa gtggaaatca tcaaccaaca attagcagat tttaaaatgt ttcagaaaga
10441 acaagtggat cctcttcaga tgaaattgca gcaggtgaat ggacttggcc agggattaat
10501 tcagagtgca ggaaaagact gtgatgtaca gggtttagaa catgacatgg aagagatcaa
10561 tgctcgatgg aatacattga ataaaaaggt cgcacaaaga attgcacagc tacaggaagc
10621 tttgttgcat tgtgggaagt ttcaagatgc cttggagcca ttgctcagct ggttggcaga
10681 taccgaggag ctcatagcca atcagaaacc tccatctgct gagtataaag tggtgaaagc
10741 acagatccaa gaacagaagt tgctccagcg gctcctagat gatcgaaagg ccacagtaga
10801 catgcttcaa gcagaaggag gcagaatagc ccagtcagca gagctggctg atagagagaa
10861 aatcactgga cagctggaga gtcttgaaag tagatggact gaactactca gtaaggcagc
10921 agccaggcaa aaacagctgg aagacatcct ggttctggcc aaacagttcc atgagacagc
10981 tgagcctatt tctgacttct tatctgtcac agagaaaaag cttgctaact cagaacctgt
11041 tggcactcag actgccaaaa tacagcagca gatcattcgg cacaaggctc tggaagaaga
11101 catagaaaac catgcaacag atgtgcacca ggcagtcaaa attgggcagt ccctctcctc
11161 cctgacatct cctgcagaac agggtgtgct gtcagaaaag atagactcat tgcaggcccg
11221 atacagtgaa attcaagacc gctgttgtcg gaaggcagcc ctacttgacc aagctctgtc
11281 taatgctagg ctgtttgggg aggatgaggt ggaggtgctc aactggctgg ctgaggttga
11341 ggacaagctc agttcagtgt tcgtaaagga tttcaaacag gatgtcctgc acaggcagca
11401 tgctgaccac ctggctttaa atgaagaaat tgttaataga aagaagaatg tagatcaagc
11461 tattaaaaat ggtcaggctc ttctaaaaca aaccacaggt gaggaggtgt tacttatcca
11521 ggaaaaacta gatggtataa agactcgtta cgcagacatc acagttacta gctccaaggc
11581 cctcagaact ttagagcaag cccggcagct ggccaccaag ttccagtcta cttatgagga
11641 actgaccggg tggctgaggg aggtggagga ggagctggca accagtggag gacagtctcc
11701 cacaggggaa cagatacccc agtttcagca gagacagaag gaattaaaga aggaggtcat
11761 ggagcacagg ctggtgttgg acacagtgaa tgaggtgagc cgtgctctct tagagctggt
11821 gccctggaga gccagagaag ggctggataa acttgtgtcc gatgctaacg agcagtacaa
11881 actagtcagt gacactattg gacaaagggt ggatgaaatt gatgctgcta ttcagagatc
11941 acaacagtat gagcaagctg ccgatgcaga actagcttgg gttgctgaaa caaaacggaa
12001 actgatggct ctgggtccaa ttcgcctgga acaggaccag accacagctc agcttcaggt
12061 acagaaggct ttctccattg acattattcg acacaaagat tcaatggatg aactcttcag
12121 tcaccgtagt gaaatctttg gcacatgtgg ggaggagcaa aaaactgtat tacaggaaaa
12181 gacagagtct ctaatacagc aatatgaagc cattagccta ctcaattcag agcgttatgc
12241 ccgcctagag cgggcccagg tcttagtaaa ccagttttgg gaaacttatg aagagctcag
12301 cccctggatt gaggaaactc gggcactaat agcacagtta ccctctccag ccattgatca
12361 tgagcagctc aggcagcaac aagaggaaat gaggcaatta agggaatcta ttgctgaaca
12421 caaacctcat attgacaaac tactaaagat aggcccacaa ctaaaggaat taaaccctga
12481 ggaaggggaa atggtggaag aaaaatacca gaaagcagaa aacatgtatg cccaaataaa
12541 ggaggaggtg cgccagcgag ccctggctct ggatgaagcc gtgtcccagt ccacacagat
12601 tacagagttt catgataaaa ttgagcctat gttggagaca ctggagaatc tttcctctcg
12661 cctgcgtatg ccaccactga tccctgctga agtagacaag atcagagagt gcatcagtga
12721 caataagagt gccaccgtgg agctagaaaa actgcagcca tcctttgagg ccttgaagcg
12781 ccgtggagag gagcttattg gacgatctca gggagcagac aaggatctgg ctgcaaaaga
12841 aatccaggat aaattggatc aaatggtatt cttctgggag gacatcaaag ctcgggctga
12901 agaacgagaa atcaaatttc ttgatgtcct tgaattagca gagaagttct ggtatgacat
12961 ggcagctctc ctgaccacca tcaaagacac ccaggatatt gtccatgact tggaaagccc
13021 aggcattgat ccttccatca tcaaacaaca ggttgaagct gctgagacta ttaaggaaga
13081 gacagatggt ctgcatgaag agctggagtt tattcggatc cttggagcag atttgatttt
13141 tgcctgtgga gaaactgaga agcctgaagt gaggaagagc attgatgaga tgaataatgc
13201 ttgggagaac ttaaacaaaa catggaaaga gaggctagaa aaacttgagg atgctatgca
13261 agctgctgtg cagtatcagg acactcttca ggctatgttt gactggctag ataacactgt
13321 gattaaactc tgcaccatgc cccctgttgg cactgacctc aatactgtta aagatcagtt
13381 aaatgaaatg aaggagttca aagtagaagt ttaccaacag caaattgaga tggagaagct
13441 taatcaccag ggtgaactga tgttaaagaa agctactgat gagacggaca gagacattat
13501 acgagaacca ctgacagaac tcaaacacct ctgggagaac ctgggtgaga aaattgccca
13561 ccgacagcac aaactagaag gggctctgtt ggcccttggt cagttccagc atgccttaga
13621 ggaactaatg agttggctga ctcataccga agagttgtta gatgctcaga gaccaataag
13681 tggagaccca aaagtcattg aagttgagct cgcaaagcac catgtcctaa aaaatgatgt
13741 tttggctcat caagccacag tggaaacagt caacaaagct ggcaatgagc ttcttgaatc
13801 cagtgctgga gatgatgcca gcagcttaag gagccgtttg gaagccatga accaatgctg
13861 ggagtcagtg ttacagaaaa cagaggagag ggagcagcag cttcagtcaa ctctgcagca
13921 ggcccagggc ttccacagtg aaattgaaga tttcctcttg gaacttacta gaatggagag
13981 ccagctttct gcatctaagc ccacaggagg acttcctgaa actgctaggg aacagcttga
14041 tacacatatg gaactctatt cccagctgaa agccaaggaa gagacttata atcaactact
14101 tgacaagggc agactcatgc ttctaagccg tgacgactct gggtctggct ccaagacaga
14161 acagagtgta gcacttttgg agcagaagtg gcatgtggtc agcagtaaga tggaagaaag
14221 aaagtcaaag ctggaagagg ccctcaactt ggcaacagaa ttccagaatt ccctacaaga
14281 atttatcaac tggctcactc tagcagagca gagtttaaac atcgcttctc caccaagcct
14341 gattctaaat actgtccttt cccagataga agagcacaag gtttttgcta atgaagtaaa
14401 tgctcatcga gaccagatca ttgagctgga tcaaactggg aatcaattaa agttccttag
14461 ccaaaagcag gatgttgttc tgatcaagaa tttgttggtg agcgtgcagt ctcgatggga
14521 gaaggttgtc cagcgatcta ttgaaagagg gcgatcacta gatgatgcca ggaagcgggc
14581 aaaacaattc catgaagctt ggaaaaaact gattgactgg ctagaagatg cagagagtca
14641 cctggactca gaactagaga tatccaatga cccagacaaa attaaacttc agctttctaa
14701 gcataaggag tttcagaaga ctcttggtgg caagcagcct gtgtatgata ccacaattag
14761 aactggcaga gcactgaaag aaaagacttt gcttcccgaa gatactcaga aacttgacaa
14821 tttcctagga gaagtcagag acaaatggga tactgtttgt ggcaagtctg tggagcggca
14881 gcacaagttg gaggaagccc tgctcttttc gggtcagttc atggatgctt tgcaggcatt
14941 ggttgactgg ttatacaagg tggagccaca gctggctgag gaccagcccg tgcacgggga
15001 ccttgacctc gtcatgaacc tcatggatgc acacaaggtt ttccagaagg aactgggaaa
15061 gcgaacagga accgttcagg tcctgaagcg gtcaggccga gagctgattg agaatagtcg
15121 agatgacacc acttgggtaa aaggacagct ccaggaactg agcactcgct gggacactgt
15181 ctgtaaactc tctgtttcca aacaaagccg gcttgagcag gccttaaaac aagcggaagt
15241 gtttcgagac acagtccaca tgctgttgga gtggctttct gaagcagagc aacttcgctt
15301 tcggggagca cttcctgatg acacagaggc cctgcagtct ctcattgaca cccataagga
15361 attcatgaag aaagtagaag aaaagcgagt ggacgttaac tcagcagtag ccatgggaga
15421 agtcatcctg gctgtctgcc accccgattg catcacaacc atcaaacact ggatcaccat
15481 catccgagct cgcttcgagg aggtcctgac atgggctaag cagcaccagc agcgtcttga
15541 aacggccttg tcagaactgg tggctaatgc tgagctcctg gaagaacttc tggcatggat
15601 ccagtgggct gagaccaccc tcattcagcg ggatcaggag ccaatcccgc agaacattga
15661 ccgagttaaa gcccttatcg ctgagcatca gacatttatg gaggagatga ctcgcaaaca
15721 gcctgacgtg gaccgggtca ccaagacata caaaaggaaa aacatagagc ctactcacgc
15781 gcctttcata gagaaatccc gcagcggagg caggaaatcc ctaagtcagc caacccctcc
15841 tcccatgcca atcctttcac agtctgaagc aaaaaaccca cggatcaacc agctttctgc
15901 ccgctggcag caggtgtggc tgttagcact ggagcggcaa aggaaactga atgatgcctt
15961 ggatcggctg gaggagttga aagaatttgc caactttgac tttgatgtct ggaggaaaaa
16021 gtatatgcgt tggatgaatc acaaaaagtc tcgagtgatg gatttcttcc ggcgcattga
16081 taaggaccag gatgggaaga taacacgtca ggagtttatc gatggcattt tagcatccaa
16141 gttccccacc accaagttag agatgactgc tgtggctgac attttcgacc gagatgggga
16201 tggttacatt gattattatg aatttgtggc tgctcttcat cccaacaagg atgcgtatcg
16261 accaacaacc gatgcagata aaatcgaaga tgaggttaca agacaagtgg ctcagtgcaa
16321 atgtgcaaaa aggtttcagg tggagcagat cggagagaat aaataccggt ttggggattc
16381 tcagcagttg cggctggtcc gtattctgcg cagcaccgtg atggttcgcg ttggtggagg
16441 atggatggcc ttggatgaat ttttagtgaa aaatgatccc tgccgagcac gaggtagaac
16501 taacattgaa cttagagaga aattcatcct accagaggga gcatcccagg gaatgacccc
16561 cttccgctca cggggtcgaa ggtccaaacc atcttcccgg gcagcttccc ctactcgttc
16621 cagctccagt gctagtcaga gtaaccacag ctgtacatcc atgccatctt ctccagccac
16681 cccagccagt ggaaccaagg ttatcccatc atcaggtagc aagttgaaac gaccaacacc
16741 aacttttcat tctagtcgga catcccttgc tggtgatacc agcaatagtt cttccccggc
16801 ctccacaggt gccaaaacta atcgggcaga ccctaaaaag tctgccagtc gccctgggag
16861 tcgggctggg agtcgagccg ggagtcgagc cagcagccgg cgaggaagtg acgcttctga
16921 ctttgacctc ttagagacgc agtctgcttg ttccgacact tcagaaagca gcgctgcagg
16981 gggccaaggc aactccagga gagggctaaa caaaccttcc aaaatcccaa ccatgtctaa
17041 gaagaccacc actgcctccc ccaggactcc aggtcccaag cgataacact gtctaagcac
17101 ccccaagcca ctatccactt tgaatcctgc tccatacatt gggtgtatat ttattctgaa
17161 cgggagaagt tatattgtta aaagtgtaaa agaataattg tgttatgaag ctgccttatt
17221 ttttttcttt ttgtaagtta ctattttcat gtgaatattt atgtagataa aatttgcctc
17281 ctggtaaccc tgtaatggat ggggcccaga aatgaaatat ttgagaaaaa caagtgaaaa
17341 ggtcaagata caaatgtgta ttaaaaaaaa aaaaaagcct attaataggg tttctgcgcg
17401 gtgcagggtt gtaaacctgc tttatctttt aggattattc ctaaatgcat cttctttata
17461 aacttgactt gctatctcag caagataaat tatattaaaa aaataagaat cctgcagtgt
17521 ttaaggaact ctttttttgt aaatcacgga cacctcaatt agcaagaact gaggggaggg
17581 ctttttccat tgtttaatgt tttgtgattt ttagctaaag agagggaacc tcatctaagt
17641 aacatttgca catgatacag caaaaggagt tcattgcaat actgtctttg gatattgttt
17701 cagtactggg tgtttaaagg acaaatagct gcta
//