LOCUS AF130356 2828 bp mRNA linear HUM 19-AUG-1999
DEFINITION Homo sapiens MALT lymphoma associated translocation (MLT) mRNA,
complete cds.
ACCESSION AF130356
VERSION AF130356.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2828)
AUTHORS Dierlamm,J., Baens,M., Wlodarska,I., Stefanova-Ouzounova,M.,
Hernandez,J.M., Hossfeld,D.K., De Wolf-Peeters,C., Hagemeijer,A.,
Van den Berghe,H. and Marynen,P.
TITLE The apoptosis inhibitor gene API2 and a novel 18q gene, MLT, are
recurrently rearranged in the t(11;18)(q21;q21)p6ssociated with
mucosa-associated lymphoid tissue lymphomas
JOURNAL Blood 93 (11), 3601-3609 (1999)
PUBMED 10339464
REFERENCE 2 (bases 338 to 2828)
AUTHORS Dierlamm,J., Baens,M., Wlodarska,I., Stefanova-Ouzounova,M.,
Hernandez,J.M., Hossfeld,D.K., De Wolf-Peeters,C., Hagemeijer,A.,
Van Den Berghe,H. and Marynen,P.
TITLE Direct Submission
JOURNAL Submitted (23-FEB-1999) Center for Human Genetics, Catholic
University of Leuven, Herestraat 49, Leuven B-3000, Belgium
REFERENCE 3 (bases 1 to 2828)
AUTHORS Dierlamm,J., Baens,M., Wlodarska,I., Stefanova-Ouzounova,M.,
Hernandez,J.M., Hossfeld,D.K., De Wolf-Peeters,C., Hagemeijer,A.,
Van Den Berghe,H. and Marynen,P.
TITLE Direct Submission
JOURNAL Submitted (19-AUG-1999) Center for Human Genetics, Catholic
University of Leuven, Herestraat 49, Leuven B-3000, Belgium
REMARK Sequence update by submitter
COMMENT On Aug 19, 1999 this sequence version replaced AF130356.1.
FEATURES Location/Qualifiers
source 1..2828
/db_xref="H-InvDB:HIT000070717"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="18"
/map="18q21"
gene 1..2828
/gene="MLT"
CDS 165..2639
/gene="MLT"
/codon_start=1
/product="MALT lymphoma associated translocation"
/protein_id="AAD38507.2"
/translation="MSLLGDPLQALPPSAAPTGPLLAPPAGATLNRLREPLLRRLSEL
LDQAPEGRGWRRLAELAGSRGRLRLSCLDLEQCSLKVLEPEGSPSLCLLKLMGEKGCT
VTELSDFLQAMEHTEVLQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQW
FKMNKEIPNGNTSELIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRS
VDGVSESKLQICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTHETKKLYM
VPYVDLEHQGTYWCHVYNDRDSQDSKKVEIIIGRTDEAVECTEDELNNLGHPDNKEQT
TDQPLAKDKVALLIGNMNYREHPKLKAPLVDVYELTNLLRQLDFKVVSLLDLTEYEMR
NAVDEFLLLLDKGVYGLLYYAGHGYENFGNSFMVPVDAPNPYRSENCLCVQNILKLMQ
EKETGLNVFLLDMCRKRNDYDDTIPILDALKVTANIVFGYATCQGAEAFEIQHSGLAN
GIFMKFLKDRLLEDKKITVLLDEVAEDMGKCHLTKGKQALEIRSSLSEKRALTDPIQG
TEYSAESLVRNLQWAKAHELPESMCLKFDCGVQIQLGFAAEFSNVMIIYTSIVYKPPE
IIMCDAYVTDFPLDLDIDPKDANKGTPEETGSYLVSKDLPKHCLYTRLSSLQKLKEHL
VFTVCLSYQYSGLEDTVEDKQEVNVGKPLIAKLDMHRGLGRKTCFQTCLMSNGPYQSS
AATSGGAGHYHSLQDPFHGVYHSHPGNPSNVTPADSCHCSRTPDAFISSFAHHASCHF
SRSNVPVETTDEIPFSFSDRLRISEK"
BASE COUNT 799 a 584 c 692 g 753 t
ORIGIN
1 ggggcgggga gcggacttcc tcctctgagg gccgtgccgc gctgccagat ttgttcttcc
61 gcccctgcct ccgcggctcg gaggcgagcg gaaggtgccc cggggccgag gcccgtgacg
121 gggcgggcgg gagccccggc agtccggggt cgccggcgag ggccatgtcg ctgttggggg
181 acccgctaca ggccctgccg ccctcggccg cccccacggg gccgctgctc gcccctccgg
241 ccggcgcgac cctcaaccgc ctgcgggagc cgctgctgcg gaggctcagc gagctcctgg
301 atcaggcgcc cgagggccgg ggctggagga gactggcgga gctggcgggg agtcgcgggc
361 gcctccgcct cagttgccta gacctggagc agtgttctct taaggtactg gagcctgaag
421 gaagccccag cctgtgtctg ctgaagttaa tgggtgaaaa aggttgcaca gtcacagaat
481 tgagtgattt cctgcaggct atggaacaca ctgaagttct tcagcttctc agccccccag
541 gaataaagat tactgtaaac ccagagtcaa aggcagtctt ggctggacag tttgtgaaac
601 tgtgttgccg ggcaactgga catccttttg ttcaatatca gtggttcaaa atgaataaag
661 agattccaaa tggaaataca tcagagctta tttttaatgc agtgcatgta aaagatgcag
721 gcttttatgt ctgtcgagtt aataacaatt tcacctttga attcagccag tggtcacagc
781 tggatgtttg cgacatccca gagagcttcc agagaagtgt tgatggcgtc tctgaatcca
841 agttgcaaat ctgtgttgaa ccaacttccc aaaagctgat gccaggcagc acattggttt
901 tacagtgtgt tgctgttgga agccctattc ctcactacca gtggttcaaa aatgaattac
961 cattaacaca tgagaccaaa aagctataca tggtgcctta tgtggatttg gaacaccaag
1021 gaacctactg gtgtcatgta tataatgatc gagacagtca agatagcaag aaggtagaaa
1081 tcatcatagg aagaacagat gaggcagtgg agtgcactga agatgaatta aataatcttg
1141 gtcatcctga taataaagag caaacaactg accagccttt ggcgaaggac aaggttgccc
1201 ttttgatagg aaatatgaat taccgggagc accccaagct caaagctcct ttggtggatg
1261 tgtacgaatt gactaactta ctgagacagc tggacttcaa agtggtttca ctgttggatc
1321 ttactgaata tgagatgcgt aatgctgtgg atgagttttt actcctttta gacaagggag
1381 tatatgggtt attatattat gcaggacatg gttatgaaaa ttttgggaac agcttcatgg
1441 tccccgttga tgctccaaat ccatataggt ctgaaaattg tctgtgtgta caaaatatac
1501 tgaaattgat gcaagaaaaa gaaactggac ttaatgtgtt cttattggat atgtgtagga
1561 aaagaaatga ctacgatgat accattccaa tcttggatgc actaaaagtc accgccaata
1621 ttgtgtttgg atatgccacg tgtcaaggag cagaagcttt tgaaatccag cattctggat
1681 tggcaaatgg aatctttatg aaatttttaa aagacagatt attagaagat aagaaaatca
1741 ctgtgttact ggatgaagtt gcagaagata tgggtaagtg tcaccttacc aaaggcaaac
1801 aggctctaga gattcgaagt agtttatctg agaagagagc acttactgat ccaatacagg
1861 gaacagaata ttctgctgaa tctcttgtgc ggaatctaca gtgggccaag gctcatgaac
1921 ttccagaaag tatgtgtctt aagtttgact gtggtgttca gattcaatta ggatttgcag
1981 ctgagttttc caatgtcatg atcatctata caagtatagt ttacaaacca ccggagataa
2041 taatgtgtga tgcctacgtt actgattttc cacttgatct agatattgat ccaaaagatg
2101 caaataaagg cacacctgaa gaaactggca gctacttggt atcaaaggat cttcccaagc
2161 attgcctcta taccagactc agttcactgc aaaaattaaa ggaacatcta gtcttcacag
2221 tatgtttatc atatcagtac tcaggattgg aagatactgt agaggacaag caggaagtga
2281 atgttgggaa acctctcatt gctaaattag acatgcatcg aggtttggga aggaagactt
2341 gctttcaaac ttgtcttatg tctaatggtc cttaccagag ttctgcagcc acctcaggag
2401 gagcagggca ttatcactca ttgcaagacc cattccatgg tgtttaccat tcacatcctg
2461 gtaatccaag taatgttaca ccagcagata gctgtcattg cagccggact ccagatgcat
2521 ttatttcaag tttcgctcac catgcttcat gtcattttag tagaagtaat gtgccagtag
2581 agacaactga tgaaatacca tttagtttct ctgacaggct cagaatttct gaaaaatgac
2641 ctccttgttt ttgaaagtta gcataatttt agatgcctgt gaaatagtac tgcacttaca
2701 taaagtgaga cattgtgaaa aggcaaattt gtatatgtag agaaagaata gtagtaactg
2761 tttcatagca aacttcagga ctttgagatg ttgaaattac attatttaat tacagacttc
2821 ctctttct
//