LOCUS       AF119711                1014 bp    mRNA    linear   HUM 05-JUL-1999
DEFINITION  Homo sapiens cysLT1 LTD4 receptor (CYSLT1) mRNA, complete cds.
ACCESSION   AF119711
VERSION     AF119711.1
KEYWORDS    .
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1014)
  AUTHORS   Lynch,K.R., O'Neill,G.P., Liu,Q., Im,D.S., Sawyer,N., Metters,K.M.,
            Coulombe,N., Abramovitz,M., Figueroa,D.J., Zeng,Z., Connolly,B.M.,
            Bai,C., Austin,C.P., Chateauneuf,A., Stocco,R., Greig,G.M.,
            Kargman,S., Hooks,S.B., Hosfield,E., Williams,D.L. Jr.,
            Ford-Hutchinson,A.W., Caskey,C.T. and Evans,J.F.
  TITLE     Characterization of the human cysteinyl leukotriene CysLT1 receptor
  JOURNAL   Nature 399 (6738), 789-793 (1999)
   PUBMED   10391245
REFERENCE   2  (bases 1 to 1014)
  AUTHORS   Lynch,K.R., O'Neill,G.P., Liu,Q., Im,D.S., Sawyer,N., Metters,K.M.,
            Coulombe,N., Abramovitz,M., Figueroa,D.J., Zeng,Z., Connolly,B.M.,
            Bai,C., Austin,C.P., Chateauneuf,A., Stocco,R., Greig,G.,
            Kargman,S., Hooks,S.B., Hosfield,E., Williams,D.L. Jr.,
            Ford-Hutchinson,A.W., Caskey,C.T. and Evans,J.F.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-1999) Pharmacology, Univ. Virginia Health
            Sciences Center, 1300 Jefferson Park Avenue, Charlottesville, VA
            22908, USA
FEATURES             Location/Qualifiers
     source          1..1014
                     /db_xref="H-InvDB:HIT000070210"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="X"
                     /map="Xq13-q21"
                     /clone="I.M.A.G.E. Consortium ID 1357580"
                     /cell_type="germinal B cells"
                     /tissue_type="tonsil"
     gene            1..1014
                     /gene="CYSLT1"
     CDS             1..1014
                     /gene="CYSLT1"
                     /note="family A (rhodopsin-like) G protein-coupled
                     receptor; target of cysteinyl leukotriene antagonists used
                     clinically in chronic treatment of asthma"
                     /codon_start=1
                     /product="cysLT1 LTD4 receptor"
                     /protein_id="AAD42285.1"
                     /translation="MDETGNLTVSSATCHDTIDDFRNQVYSTLYSMISVVGFFGNGFV
                     LYVLIKTYHKKSAFQVYMINLAVADLLCVCTLPLRVVYYVHKGIWLFGDFLCRLSTYA
                     LYVNLYCSIFFMTAMSFFRCIAIVFPVQNINLVTQKKARFVCVGIWIFVILTSSPFLM
                     AKPQKDEKNNTKCFEPPQDNQTKNHVLVLHYVSLFVGFIIPFVIIIVCYTMIILTLLK
                     KSMKKNLSSHKKAIGMIMVVTAAFLVSFMPYHIQRTIHLHFLHNETKPCDSVLRMQKS
                     VVITLSLAASNCCFDPLLYFFSGGNFRKRLSTFRKHSLSSVTYVPRKKASLPEKGEEI
                     CKV"
BASE COUNT          280 a          209 c          183 g          342 t
ORIGIN      
        1 atggatgaaa caggaaatct gacagtatct tctgccacat gccatgacac tattgatgac
       61 ttccgcaatc aagtgtattc caccttgtac tctatgatct ctgttgtagg cttctttggc
      121 aatggctttg tgctctatgt cctcataaaa acctatcaca agaagtcagc cttccaagta
      181 tacatgatta atttagcagt agcagatcta ctttgtgtgt gcacactgcc tctccgtgtg
      241 gtctattatg ttcacaaagg catttggctc tttggtgact tcttgtgccg cctcagcacc
      301 tatgctttgt atgtcaacct ctattgtagc atcttcttta tgacagccat gagctttttc
      361 cggtgcattg caattgtttt tccagtccag aacattaatt tggttacaca gaaaaaagcc
      421 aggtttgtgt gtgtaggtat ttggattttt gtgattttga ccagttctcc atttctaatg
      481 gccaaaccac aaaaagatga gaaaaataat accaagtgct ttgagccccc acaagacaat
      541 caaactaaaa atcatgtttt ggtcttgcat tatgtgtcat tgtttgttgg ctttatcatc
      601 ccttttgtta ttataattgt ctgttacaca atgatcattt tgaccttact aaaaaaatca
      661 atgaaaaaaa atctgtcaag tcataaaaag gctataggaa tgatcatggt cgtgaccgct
      721 gcctttttag tcagtttcat gccatatcat attcaacgta ccattcacct tcatttttta
      781 cacaatgaaa ctaaaccctg tgattctgtc cttagaatgc agaagtccgt ggtcataacc
      841 ttgtctctgg ctgcatccaa ttgttgcttt gaccctctcc tatatttctt ttctgggggt
      901 aactttagga aaaggctgtc tacatttaga aagcattctt tgtccagcgt gacttatgta
      961 cccagaaaga aggcctcttt gccagaaaaa ggagaagaaa tatgtaaagt atag
//