LOCUS AH007601 10061 bp DNA linear HUM 10-JUN-2016
DEFINITION Homo sapiens chromosome X Wiskott-Aldrich Syndrome protein (WASP)
gene, complete cds.
ACCESSION AH007601 AF115548 AF115549
VERSION AH007601.3
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 10061)
AUTHORS Hagemann,T.L. and Kwan,S.P.
TITLE The identification and characterization of two promoters and the
complete genomic sequence for the Wiskott-Aldrich syndrome gene
JOURNAL Biochem. Biophys. Res. Commun. 256 (1), 104-109 (1999)
PUBMED 10066431
REFERENCE 2 (bases 1 to 10061)
AUTHORS Kwan,S.-P. and Hagemann,T.L.
TITLE Direct Submission
JOURNAL Submitted (22-DEC-1998) Immunology/Microbiology, Rush Medical
School, 1750 W. Harrison Street, Rm 1595 Jelke Bldg., Chicago, IL
60612, USA
REFERENCE 3 (bases 1 to 10061)
AUTHORS Kwan,S.-P. and Hagemann,T.L.
TITLE Direct Submission
JOURNAL Submitted (16-JUL-1999) Immunology/Microbiology, Rush Medical
School, 1750 W. Harrison Street, Rm 1595 Jelke Bldg., Chicago, IL
60612, USA
REMARK Sequence update by submitter
COMMENT On or before Jun 10, 2016 this sequence version replaced
AF115548.1, AF115549.2, AH007601.2.
FEATURES Location/Qualifiers
source 1..10061
/organism="Homo sapiens"
/mol_type="genomic DNA"
/db_xref="taxon:9606"
/chromosome="X"
/map="Xp11.23"
gene 1..9817
/gene="WASP"
misc_feature 1..284
/gene="WASP"
/note="alternate promoter region"
mRNA join(285..434,2210..2375,2673..2813,3937..4023,4124..4226,
4336..4377,4471..4524,5171..5345,6444..6486,6690..6843,
7050..7456,7710..7824,9497..9817)
/gene="WASP"
/product="Wiskott-Aldrich Syndrome protein"
/note="transcript with alternate 5'UTR"
exon 285..434
/gene="WASP"
/note="alternate untranslated exon"
gap 478..577
/estimated_length=unknown
repeat_region 580..725
/gene="WASP"
/note="LINE"
/rpt_family="L1"
/rpt_type=dispersed
repeat_region 1004..1303
/gene="WASP"
/note="SINE"
/rpt_family="Alu"
/rpt_type=dispersed
repeat_region 1460..1776
/gene="WASP"
/note="SINE"
/rpt_family="Alu"
/rpt_type=dispersed
mRNA join(2153..2375,2673..2813,3937..4023,4124..4226,
4336..4377,4471..4524,5171..5345,6444..6486,6690..6843,
7050..7456,7710..7824,9497..9817)
/gene="WASP"
/product="Wiskott-Aldrich Syndrome protein"
CDS join(2244..2375,2673..2813,3937..4023,4124..4226,
4336..4377,4471..4524,5171..5345,6444..6486,6690..6843,
7050..7456,7710..7824,9497..9552)
/gene="WASP"
/codon_start=1
/product="Wiskott-Aldrich Syndrome protein"
/protein_id="AAD26691.1"
/translation="MSGGPMGGRPGGRGAPAVQQNIPSTLLQDHENQRLFEMLGRKCL
TLATAVVQLYLALPPGAEHWTKEHCGAVCFVKDNPQKSYFIRLYGLQAGRLLWEQELY
SQLVYSTPTPFFHTFAGDDCQAGLNFADEDEAQAFRALVQEKIQKRNQRQSGDRRQLP
PPPTPANEERRGGLPPLPLHPGGDQGGPPVGPLSLGLATVDIQNPDITSSRYRGLPAP
GPSPADKKRSGKKKISKADIGAPSGFKHVSHVGWDPQNGFDVNNLDPDLRSLFSRAGI
SEAQLTDAETSKLIYDFIEDQGGLEAVRQEMRRQEPLPPPPPPSRGGNQLPRPPIAGG
NKGRSGPLPPVPLGIAPPPPTPRGPPPPGRGGPPPPPPPATGRSGPLPPPPPGAGGPP
MPPPPPPPPPPPSSGNGPAPPPLPPALVPAGGLAPGGGRGALLDQIRQGIQLNKTPGA
PESSALQPPPQSSEGLVGALMHVMQKRSRAIHSSDEGEDQAGDEDEDDEWDD"
repeat_region 2417..2474
/gene="WASP"
/note="low complexity"
/rpt_type=tandem
repeat_region 4552..4999
/gene="WASP"
/rpt_type=tandem
repeat_region 5405..5491
/gene="WASP"
/rpt_type=tandem
repeat_region 5492..5649
/gene="WASP"
/rpt_family="MER1"
/rpt_type=dispersed
repeat_region 5655..6255
/gene="WASP"
/rpt_type=tandem
repeat_region 6971..7013
/gene="WASP"
/note="SINE"
/rpt_family="MIR"
/rpt_type=dispersed
repeat_region 8104..8401
/gene="WASP"
/note="SINE"
/rpt_family="Alu"
/rpt_type=dispersed
repeat_region 8527..8839
/gene="WASP"
/note="SINE"
/rpt_family="Alu"
/rpt_type=dispersed
repeat_region 8967..9142
/gene="WASP"
/note="SINE"
/rpt_family="Alu"
/rpt_type=dispersed
repeat_region 9875..9950
/rpt_type=tandem
repeat_region 10001..10055
/note="LINE"
/rpt_family="L2"
/rpt_type=dispersed
BASE COUNT 2512 a 2616 c 2562 g 2271 t
ORIGIN
1 aattgccagc tcgtgtgcgg gagggccggg tcaagactaa gtcaaaggag gagagggcaa
61 cgcggtgggc aggagagagg ccaacggccg cccggggcga ggggagccgg taggacggga
121 ccaggactgg ccgacccggc cccgcgcggg gaagggggcg ccttcctccc acaacacaaa
181 acggtgcgcc cgggttggcc gcccctcccc agtggtgcgg ccccgggtgg acgcttccgt
241 gcgcgcgtcc atgcccagcc attgcgggct gcgggctcca agggtcgcac acgctggaga
301 gtgcaggttg ccgggtccac ccacagggct gtagacaccc ctagggtcac acagacaagg
361 ctctggacac ccacaggggc acacacattg gggagtgggc actcctgggc tcacaaagac
421 tgaggcgcag gaaggtaggg cgcgcccgcc cagagggagt tggtggtggc tgagggtnnn
481 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
541 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnctg cagtgttgct cccaacagca
601 agaaccagaa gcagcccaaa gggctgttac aggagaatat ggacacccag gctgcacatg
661 cacaccatgg aatgctgtat ggcagtggaa ataaatgaac agctaccact ataggcaaac
721 aggaatcaca gcaacagcca agagtgaagg cgtggaggga cgagaccatg cactcacacc
781 tggcctgcct ggctcgcact ccgggcaaag gggtcagaac agtgactggc acacacgtta
841 agtgctatgt gagtgttaag ataaaactag gatgtccagt ggggagaaag caagcctttg
901 aagattatgt gcttttacaa acttcaagtg caatgaaaac taaacaagat gttgttcagg
961 cattcatata tgatataaag ttcctttctt taaaaaaggg atgggctggg cacggtggct
1021 cacgcctgta attctaatac tttgggaggc cgaggcaggt ggatcacgag gtcgagaaat
1081 cgagaccatc ctggccaaca tggtgaaacc ctgtctctac taaaaataca aaaaaattag
1141 ctgggcgtgg tggcgtgtgc ctgtagtccc agctacttgg gaggctgagg caggagagtc
1201 acttgaaccc gggaggcaaa ggttgcagtg agccgagatc gtgccaccgc actccagcct
1261 ggcgacagag tgagactcca tctcaaaaaa aaaaagaaaa aaaaaagtat gacaagcaga
1321 aagtaatttg ggagctgcgg ggaggcaagg gtaagggatg gggaagtgga ccagaggcat
1381 atgcgtcatt ggcagtgtct aagcactcac gataggcgtg gatcacaggg gctcgctctg
1441 taattaaaag gaaaagggtt tttgttgtgt tgttgttgtt gctgtttttg agacaagggt
1501 cttgctctgt catcatccag gctggagtgc agtggtgcag tctcagctca ctgcaacctc
1561 cgcctcctgg gttcaagcga ttctcctgcc tcagcctcct gagcagctag gactacaggt
1621 gtgtgccacc atgcctggct aatttttgta ttttttagtg gaaatggggt tttgccatgt
1681 tgcccaggct cgtcttgaac tcctgacctc aagtgatcca ctcgtctcgg cctcccaaag
1741 tgctgggatt acaggtgtga gctattgtcc ccagccaaaa ggaaaagttt tactgtagta
1801 acccttccgg actagggacc tcgggcctca gcctcaggct acctaggtgc tttagaaagg
1861 aggccaccca ggcccatgac tactccttgc cacagggagc cctgcacaca gatgtgctaa
1921 gctctcgctg ccagccagag ggaggaggtc tgagccagtc agaaggagat gggccccaga
1981 gagtaagaaa gggggaggag gacccaagct gatccaaaag gtgggtctaa gcagtcaagt
2041 ggaggagggt tccaatctga tggcggaggg cccaagctca gcctaacgag gaggccaggc
2101 ccaccaaggg gcccctggag gacttgtttc ccttgtccct tgtggttttt tgcatttcct
2161 gttcccttgc tgctcattgc ggaagttcct cttcttaccc tgcacccaga gcctcgccag
2221 agaagacaag ggcagaaagc accatgagtg ggggcccaat gggaggaagg cccgggggcc
2281 gaggagcacc agcggttcag cagaacatac cctccaccct cctccaggac cacgagaacc
2341 agcgactctt tgagatgctt ggacgaaaat gcttggtgag ctggggatct cctgcccccg
2401 ccccgtcccc accgtttctt cctcttcctc tcctccttct ctctcttccc ctcctcccgc
2461 tcctcctttc cctctccatc atctcctctc ctagaatttc ccgtcataat ccacccttcc
2521 caggaagatc tcaatgtcta cttgccttcc ctctggctgc agctcttcct ttgggcccat
2581 gactgtcatg aggcaggaag gaccaggtct ggctccaaga ccttgtggct acccctgacc
2641 agactccact gacccctgct ttcctctccc agacgctggc cactgcagtt gttcagctgt
2701 acctggcgct gccccctgga gctgagcact ggaccaagga gcattgtggg gctgtgtgct
2761 tcgtgaagga taacccccag aagtcctact tcatccgcct ttacggcctt caggtgaccc
2821 ccccaccccc gactggactt gcaagccagt tctcaacccg caaacccaga tctgtgtcca
2881 tatgtgtcca tagcttcaag acctcagacc tgatcagtga atccctgagc cccagaacca
2941 aagactcatc cagatggcaa actctgactt gcctttctaa gtctgcaatg actggcccca
3001 gtctccgtat caagatctct aaagccccca gtattagtct gctgcctaag cctaatcttt
3061 tccacaaatt ccaataaatg agcactgtat ttgtacctga acctcaaatc tattctaaac
3121 tcaacatttt gcatcccagg aatctctcat caaaactcct gaaccccaga tgtttgccaa
3181 gctcctaagt cataaatctg ttcaacaaac cccaaagttg aatattccat tgatccttga
3241 actccaaatc tgtccttcta aatccacagc acagacccca gagttcccat attaaaattc
3301 ctgaacactc aaataccgag gtagttctta agcaaaaagt cttttccaca atcccctgac
3361 ctgaactttc taggtttaag ccccaaattc atccttttaa acccataaag atggacccag
3421 cataacttcc agatcccaag gctatcaaat atccaccaaa ctcctaaacc ataactctct
3481 ccacaaaccc caaattgcac ttactttagc tggactcccc gcgaaactcc caagtctatg
3541 tgtctgaact tcaaatctca actccaaccc ccaaatacta gaatcctacc tgtcatgaat
3601 tggggctggg gtggtggggg agggcatgga ttgaatctgt gaatgagcct caacttccta
3661 agactagagt cctaaattat gaaattcaag cccccaagtc ccagatctag ggccccaaac
3721 cccaaatcca aacctctcac aaaagtgtat ggctcccaga ctatacccca caatccacac
3781 ccttagacac caactctctg gtgctgagct gaaaatctcc aaaccagact atgaggctcc
3841 caaatccaga caccctgctc cctgcccagc taacaaaagc ctgccacccc cggcgtgcct
3901 cagtgccact gtgcctccca ccctacacct ctccaggctg gtcggctgct ctgggaacag
3961 gagctgtact cacagcttgt ctactccacc cccaccccct tcttccacac cttcgctgga
4021 gatgtaagtg atcaaccagc cctcgggcct cacttggggt gtggagagga gatgggaaag
4081 ttgcggggga cctgggaggc ggctgacccc aaggtatgtg caggactgcc aagcggggct
4141 gaactttgca gacgaggacg aggcccaggc cttccgggcc ctcgtgcagg agaagataca
4201 aaaaaggaat cagaggcaaa gtggaggtga ggaggccaca ggggaggaaa ggaagttggg
4261 cagaggtgag tgcaagcctg gggaactaga aaagtcccct ctcatggtcc tggctcccaa
4321 tccatctatc cacagacaga cgccagctac ccccaccacc aacaccagcc aatgaaggtg
4381 agtcctctag tgcaagtagg ggtaataagg ggctagccca ggaacctgtg gcagggctgt
4441 gataactctc tacacattcc atcttcccag agagaagagg agggctccca cccctgcccc
4501 tgcatccagg tggagaccaa ggaggtgcgt gctgattctt ccctgtgtct ctggatggat
4561 gggtaagagt ggatggagga atgaggagtt ggatgggtgc ctaagtgggt gaatggatag
4621 gtagattgat aggtatgtgg atggacgagc gggtgcatgg atgtgtggac tgatggatgg
4681 gtggatggat tggcggcaga tggctgagta gagggatgaa ttgatgggag gatgaaagtc
4741 taagtagata gatgcatagg tgaatgggta tgtggataaa tgaatgaaaa ggtagatgga
4801 tgactgagta aattaatcaa tgagtgaatg aatgaacagt gaataaatga ctaaatgaca
4861 agtttcagtc agtgaagaaa gcatgattga atgaataaat gagtaaatga atattttaac
4921 aaattcatta gtcaatgagc cagtgaatga taaagcatga gggaatgaaa acatgaatga
4981 atcagtgaat gtatgaatgg tttgtgggat ccacccactt ctccatagac cctacttgaa
5041 cccttcaccc actacctcca tgaccatcca acacacacac agatttccct caaggcttcc
5101 gtttcttgcc cctgtgcttt ggttggttgg taagtgggtc aatgagccaa ccaccctatt
5161 ttccccacag gccctccagt gggtccgctc tccctggggc tggcgacagt ggacatccag
5221 aaccctgaca tcacgagttc acgataccgt gggctcccag cacctggacc tagcccagct
5281 gataagaaac gctcagggaa gaagaagatc agcaaagctg atattggtgc acccagtgga
5341 ttcaagtgag agccactccc cagtggaccc acagattcct gggggcagag gggcacatga
5401 acaagtggac agctgagtga atggaaggat gggcagatgg gcacatggct gggtggctga
5461 gtgggtaaat gggtggttgg ataggtaggt gcagggctgg gtctagggag aggtaaataa
5521 ggcaccaagg gtacaaaatt taaggaggca ctcactctca gaggcatgca actgtaattc
5581 ctgactctca gagtgagtga ctcacttaaa ttttgcaccc taggcacctt acttgcctca
5641 ccctgggccc actctgggtg ggctgttagg agagcaggtg ggtgggcagg tgaacaaatg
5701 gatagataga tgaggtagat gatggatgag aagggctggt gggtaggtgg gtgagtggat
5761 gggtggatgg atggataaat gaatggatga atgaatgggt tgaagaatga atggataagt
5821 ggttggatgg acaagtttat gggtggatgg gttgatggga ggtgcgtgga tagatagatg
5881 ggtgagtgga taggtgtgtg gacagattga tatgcaggct gattggctca cagacaaggt
5941 ggatggggat ggacaggtgg acagatacgt ggatgaatgg acagttcaat ggataagtga
6001 acagaagtgt gtggttgcat gggtagaaaa atgagtggat ggatagatgg aaaggtgggc
6061 acatgggtag gtggatgggt ggatggacaa gtgtgtgtga ggacagactg gtggacaaat
6121 gggtgaacag acatatgtgg gcagatagtt gcagagacag atgtatggac agatcagtag
6181 tccaacagat gaatgtgaat gaataggtgg acaaatgcat gggatagatg gggaaagagg
6241 gatgggtgga tggatcagca ccacaaacta tggagccctt ctaattccat aactcctgcc
6301 tatactcatt cactcattca gtctcattca ttaattctgg cccctcagag tctctttggg
6361 caggagaggg caagagggtt tcactatgaa gggagggaag gaagggcagt gaggattcac
6421 tggagtctct tcacctctcc caggcatgtc agccacgtgg ggtgggaccc ccagaatgga
6481 tttgacgtga gtaacttcag agtctcttgg actccactaa acttccaccc acccttccaa
6541 agaccactgc tgagacccca cccccagatc gtgcccttcc cacacccctc tcagatccct
6601 tgctgggatg gacccaacga caatccatgt cgcttgtctc ctcgccttat tcctctactc
6661 ctgcccctgg cctttttcct cctgggcagg tgaacaacct cgacccagat ctgcggagtc
6721 tgttctccag ggcaggaatc agcgaggccc agctcaccga cgccgagacc tctaaactta
6781 tctacgactt cattgaggac cagggtgggc tggaggctgt gcggcaggag atgaggcgcc
6841 agggtgagac cctgcttcca tacgctccct tctctagccc aagcagctca tagctaagat
6901 acgcactaag tcactcagtc cttatgggag cacctatact gcttcagtca ggagttggtc
6961 agtgggggta cccattttac aaatgagcaa aactgaggct cagaagaaat caatgagagt
7021 tacagctatg tgttataccc cctccacaga gccacttccg ccgcccccac cgccatctcg
7081 aggagggaac cagctccccc ggccccctat tgcggggggt aacaagggtc gttctggtcc
7141 actgccccct gtacctttgg ggattgcccc acccccacca acaccccggg gacccccacc
7201 cccaggccga gggggccctc caccaccacc ccctccagct actggacgtt ctggaccact
7261 gccccctcca ccccctggag ctggtgggcc acccatgcca ccaccaccgc caccaccgcc
7321 accgccgccc agctccggga atggaccagc ccctccccca ctccctcctg ctctggtgcc
7381 tgccgggggc ctggcccctg gtgggggtcg gggagcgctt ttggatcaaa tccggcaggg
7441 aattcagctg aacaaggtga ggacaggcag gatggaggat tgggggtcta ggactctggg
7501 gtgtcccgtc taagtcagga tactgggggg ctgaggccag gactgaggag agtgccaggc
7561 cttagggatt cagtgatagg gttgaaaggt tggtgggaag ccttgaaggg gactggagtg
7621 tgtgggagag aaaatattga tggaggggcg gggagaaatg ctcctttccc aggccctaag
7681 ccctctgtgc tgatccctgc ctgctgcaga cccctggggc cccagagagc tcagcgctgc
7741 agccaccacc tcagagctca gagggactgg tgggggccct gatgcacgtg atgcagaaga
7801 gaagcagagc catccactcc tccggtgagc tgatcctgcc ggggcctcaa acctggctcc
7861 cagggctagc actggcctca aaacaatccc agcagtcacc accaatagtg acatcagccc
7921 catctgtttg acagcattaa catgaatctt gtgtcagcct cgtttttgac aatgttaaca
7981 ttaagtcatt atgtgacaat aatataatta actccaactt tgacagtaat attaacatta
8041 atgccagggt gtgtccacaa tattaatgtc attcccacat gttcagtact actaacatca
8101 gctggccggg cgcggtggct catgcctgta atccaggaac tttgggaggc taaggcagga
8161 ggatcacttg agcccaggag ttcgagacca gcctgggcaa tatagtgaga cctcgtttcc
8221 ataaaaacta aattcaaaaa aagtagtcaa gcatagtggt gtgtgcctgt ggtcccagct
8281 acttgggagg ctgaggtggg aggattgctt gaccctggga ggtcaaggca gcagtgatcc
8341 atgattgtgc cactgcactc cagcctgggt gacagagatc ctatctcaaa aaaaaaaaaa
8401 attaacccat tatgtgatga caatattatg aagaacacta ttgttgacaa tattaatttt
8461 aattccatgt attaacagat ttacattaat tcattatgac gtaacctaat ctaatctttt
8521 aaaaaatttt tttgaaacag ggtctcgctc tgtgtcccag gctggagtac agtggtgcaa
8581 tcatggctca gtgcagcctc aacctcccag gctcaagcga tcctcccgcc tcagctccca
8641 aagtagctgg gactacaggc gtgtgccacc atacctggct aatttttggt gtttttttgg
8701 tagtgatgag ctctcactac caagctctca ctactctcat gttgcccagg ctgctctgca
8761 actccagggc tcaagcgatc tgccccgcct cagcctccca gagtgctggg attacaggca
8821 tgagccacca ggcctggctg ttaacctatc tttttataat aatgttacta ttactctctt
8881 aatctgtcag caatactgtc actaatccat tatatgatgc aatattagta tcaacctact
8941 ataggaactt catctttcga caatgatttt tttttttctt ttgagacgga gtcttggtct
9001 gtcacccagg ctggagtgca gtggcgcgat cttggctaac tgcagactct gcctcctggg
9061 ttcaagcgat tctcctgcct cagccttccg agtagctggg actacaggca cgccactacg
9121 cccagctaat tttgatgtta ttgtcattaa ccccattatg tgtcaaaaat attagcgtta
9181 accagacagg aagcaataat atattatcac acctttgcta atattattta aattcaccct
9241 attatgtgat aaataggtta acattaaccc tttgtttgac aatatctcga ctaaccacat
9301 ttttgacagc ataaacttca actccaacta gaactcagac cccaactata atccctttct
9361 tgtcccaaat ggaaactcta acttgccctc ctctagcatg agacctcaga accccagggt
9421 ccagtcctca cctcccaggc cctatgaagc cccccaccaa cctcccaggg catcttatct
9481 ttctctttcc ctccagacga aggggaggac caggctggcg atgaagatga agatgatgaa
9541 tgggatgact gagtggctga gttacttgct gccctgtgct cctccccgca ggacatggct
9601 ccccctccac ctgctctgtg cccaccctcc actctcctct tccaggcccc caacccccca
9661 tttcttcccc accaacccct ccaatgctgt tatccctgcc tggtcctcac actcacccaa
9721 caatcccaag gcccttttta tacaaaaatt ctcagttctc ttcactcaag gatttttaaa
9781 gaaaaataaa agaattgtct ttctgtctct ctataaatct cagtctgttt acattccaaa
9841 tgtgggaatg gggtcccttt cccccaaagt cccttttatt catttatccc attttattta
9901 tttagactta catgtatata ttcattcatt catttattcc ctcagtcatt tagcctgtat
9961 ttctttgttt ccttctgccc ctctgtcttt caacatttat tgtcaggtac tattttaggg
10021 gctaggaatc aagaagtggg aaaaaaaaca gacaagaatt c
//