LOCUS AF056490 3396 bp mRNA linear HUM 25-JUL-2016
DEFINITION Homo sapiens cAMP-specific phosphodiesterase 8A (PDE8A) mRNA,
partial cds.
ACCESSION AF056490
VERSION AF056490.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3396)
AUTHORS Fisher,D.A., Smith,J.F., Pillar,J.S., St Denis,S.H. and Cheng,J.B.
TITLE Isolation and characterization of PDE8A, a novel human
cAMP-specific phosphodiesterase
JOURNAL Biochem. Biophys. Res. Commun. 246 (3), 570-577 (1998)
PUBMED 9618252
REFERENCE 2 (bases 1 to 3396)
AUTHORS Fisher,D.A., Smith,J.F., Pillar,J.S., St Denis,S.H. and Cheng,J.B.
TITLE Direct Submission
JOURNAL Submitted (31-MAR-1998) Molecular Sciences, Pfizer Central
Research, Groton, CT 06340, USA
FEATURES Location/Qualifiers
source 1..3396
/db_xref="H-InvDB:HIT000064731"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene <1..3396
/gene="PDE8A"
CDS <1..2142
/gene="PDE8A"
/note="PDE8A1"
/codon_start=1
/product="cAMP-specific phosphodiesterase 8A"
/protein_id="AAC39763.1"
/translation="LACFLDKHHDIIIIDHRNPRQLDAEALCRSIRSSKLSENTVIVG
VVRRVDREELSVMPFISAGFTRRYVENPNIMACYNELLQLEFGEVRSQLKLRACNSVF
TALENSEDAIEITSEDRFIQYANPAFETTMGYQSGELIGKELGEVPINEKKADLLDTI
NSCIRIGKEWQGIYYAKKKNGDNIQQNVKIIPVIGQGGKIRHYVSIIRVCNGNNKAEK
ISECVQSDTRTDNQTGKHKDRRKGSLDVKAVASRATEVSSQRRHSSMARIHSMTIEAP
ITKVINVINAAQESSPMPVTEALDRVLEILRTTELYSPQFGAKDDDPHANDLVGGLMS
DGLRRLSGNEYVLSTKNTQMVSSNIITPISLDDVPPRIARAMENEEYWDFDIFELEAA
THNRPLIYLGLKMFARFGICEFLHCSESTLRSWLQIIEANYHSSNPYHNSTHSADVLH
ATAYFLSKERIKETLDPIDEVAALIAATIHDVDHPGRTNSFLCNAGSELAILYNDTAV
LESHHAALAFQLTTGDDKCNIFKNMERNDYRTLRQGIIDMVLATEMTKHFEHVNKFVN
SINKPLATLEENGETDKNQEVINTMLRTPENRTLIKRMLIKCADVSNPCRPLQYCIEW
AARISEEYFSQTDEEKQQGLPVVMPVFDRNTCSIPKSQISFIDYFITDMFDAWDAFVD
LPDLMQHLDNNFKYWKGLDEMKLRNLRPPPE"
BASE COUNT 1079 a 717 c 681 g 919 t
ORIGIN
1 cttgcctgtt tcctggacaa acatcatgac attatcatca tagaccacag aaatcctcga
61 cagctggatg cagaggcact gtgcaggtct atcagatcat caaaactctc agaaaacaca
121 gttattgttg gtgtagtacg cagggtggat agagaagagt tgtccgtaat gcctttcatt
181 tctgctggat ttacaaggag gtatgtagaa aaccccaaca tcatggcctg ctacaatgaa
241 ctgctccagc tggagtttgg agaggtgcga tcacaactga aactcagggc ttgtaactca
301 gtattcactg cattagaaaa cagtgaagat gcaattgaaa ttacaagcga agaccgtttt
361 atacagtatg caaatcctgc atttgaaaca acaatgggct atcagtcagg tgaattaata
421 gggaaggagt taggagaagt gcctataaat gaaaaaaagg ctgacttgct cgatactata
481 aattcatgca tcaggatagg caaggagtgg caaggaattt actatgccaa aaagaaaaac
541 ggagataata tacaacaaaa tgtgaagata atacctgtca ttggacaggg aggaaaaatt
601 agacactatg tgtccattat cagagtgtgc aatggcaaca ataaggctga gaaaatatcc
661 gaatgtgttc agtctgacac tcgtacagat aatcagacag gcaaacataa agacaggaga
721 aaaggctcac tagacgtcaa agctgttgcc tcccgtgcaa ctgaagtttc cagccagaga
781 cgacactctt ccatggcccg gatacattcc atgacaattg aggcgcccat caccaaggta
841 atcaatgtta tcaatgctgc ccaggaaagt agtcccatgc ctgtgacaga agccctagac
901 cgtgtgctgg aaattctaag aaccactgag ttatattcac cacagtttgg tgctaaagat
961 gatgatcccc atgccaatga ccttgttggg ggcttaatgt ctgatggttt gcgaagacta
1021 tcagggaatg aatatgttct ttcaacaaaa aacactcaaa tggtttcaag caatataatc
1081 actcccatct cccttgatga tgtcccacca cggatagctc gggccatgga aaatgaggaa
1141 tactgggact ttgatatttt tgaactggag gctgccaccc acaataggcc tttgatttat
1201 cttggtctca aaatgtttgc tcgctttgga atctgtgaat tcttacactg ctccgagtca
1261 acgctaagat catggttaca aattatcgaa gccaattatc attcctccaa tccctaccac
1321 aattctacac attctgctga tgtgcttcat gccactgcct attttctctc caaggagagg
1381 ataaaggaaa ctttagatcc aattgatgag gtcgctgcac tcatcgcagc caccattcat
1441 gatgtggatc accctgggag aaccaactcc ttcctgtgta atgctggaag tgagctggcc
1501 attttgtaca atgacactgc tgtgctggag agccaccatg cggccttggc cttccagctg
1561 accactggag atgataaatg caatatattt aaaaacatgg agaggaatga ttatcggaca
1621 ctgcgccagg ggattatcga catggtctta gccacagaaa tgacaaagca ctttgagcat
1681 gtcaacaaat ttgtcaacag catcaacaaa cccttggcaa cactagaaga aaatggggaa
1741 actgataaaa accaggaagt gataaacact atgcttagga ctccagagaa ccggacccta
1801 atcaaacgaa tgctgattaa atgtgctgat gtgtccaatc cctgccgacc cctgcagtac
1861 tgcatcgagt gggctgcacg catttcggaa gaatattttt ctcagactga tgaagagaag
1921 cagcagggct tacctgtggt gatgccagtg tttgacagaa atacctgcag catccccaaa
1981 tcccaaatct ctttcattga ttacttcatc acagacatgt ttgatgcttg ggatgccttt
2041 gtagacctgc ctgatttaat gcagcatctt gacaacaact ttaaatactg gaaaggactg
2101 gacgaaatga agctgcggaa cctccgacca cctcctgaat agtgggagac accacccaga
2161 gccctgaagc tttgttcctt cggtcatttg gaattcctga gggcagccag agctccttgg
2221 tcctttcagt actaggcaga acagcccccg atctgcatag cctgtgaaag cccacgggga
2281 catcagtaac cttctgcagc caccatccaa tgccattact gtcaagtgag acttggccac
2341 tgtagcctgg gcctgctgca ggagctcttc agaaaggcac atgaggacca cggtttgcct
2401 cagtttctgg taaaacacaa ggtctggagt gcccctgcaa agggtattga tggacttcct
2461 gccagtgaca gagcatgtct attgcaaaca attctctcag ttacgttcag cacttaagaa
2521 cggctaatgg caataggatc tttagcaact ttttcacatc atagaaggtg caatcgctca
2581 cttgggaaca ctactgagag tgacttctct tttaaaattg agtagcagat gaaaaattaa
2641 aatttgaact tgattattaa tatcaattaa aatgttttat ttattttatt aaaagctcaa
2701 tattttctat gaattcaaaa atacttcaga gccaaagcca acttcaaata ccgtgaccaa
2761 atttacatga ttcatattca ttatgcatta cttggtatac agacttattt tcataatgca
2821 aattaataaa atgacacttt tactgcacta tagaaatatt catgtatgtt aaacttttct
2881 gattgaggct aactggaaaa agctggggtc gtattctaag tgctaaagaa ggctgcttct
2941 actgtataga acccagggct ctgaaacagc tctagccgcc taatgcactt cacaggtaac
3001 tccccaaggt aaaactagac tctcttgttg gttcgcaaag aaaagttagg acttaacact
3061 tttttctaaa attttataat tcaatttcca aaagtctact ctattttata ctgtttctac
3121 aaaatattcc ttataaaaac aaagaacaaa aattgaatat ttaatgaatt gacattttat
3181 aaccaacctg tttttatcta cggtgggaat ctttgatgcc agaaatttat aaagaggttc
3241 tgtatcttca caccttgaat aagcataata ccataaaaaa tgacacttga catgtcaatg
3301 tatttgtcat ttcattttaa actcgtattt gtggtttttt tcccagataa aaatgaaatt
3361 aaaccatttc tttttaagaa aaaaaaaaaa aaaaaa
//