LOCUS       AH005826S03              648 bp    DNA     linear   HUM 26-SEP-2002
DEFINITION  Homo sapiens glucokinase (GCK) gene, exon 1c.
ACCESSION   AF041014 M93280
VERSION     AF041014.1
KEYWORDS    .
SEGMENT     3 of 11
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 648)
  AUTHORS   Stoffel,M., Froguel,P., Takeda,J., Zouali,H., Vionnet,N., Nishi,S.,
            Weber,I.T., Harrison,R.W., Pilkis,S.J., Lesage,S., Vaxillaire,M.,
            Velho,G., Sun,F., Iris,F., Passa,P., Cohen,D. and Bell,G.I.
  TITLE     Human glucokinase gene: isolation, characterization, and
            identification of two missense mutations linked to early-onset
            non-insulin-dependent (type 2) diabetes mellitus
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 89 (16), 7698-7702 (1992)
   PUBMED   1502186
REFERENCE   2  (bases 1 to 648)
  AUTHORS   Bell,G.I.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-APR-1993) Howard Hughes Medical Institute, Depts of
            Biochemistry and Molecular Biology and of Medicine, The University
            of Chicago, 5841 South Maryland Avenue MC1028, Chicago, IL 60637,
            USA
FEATURES             Location/Qualifiers
     source          1..648
                     /organism="Homo sapiens"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:9606"
                     /tissue_type="placenta"
                     /clone_lib="Stratagene cat. no. 946203"
     exon            341..464
                     /gene="GCK"
                     /note="1c; alternative exon; liver specific"
BASE COUNT          130 a          244 c          133 g          141 t
ORIGIN      
        1 ctgcagcatc tgcccaggga ctgccctggc ccttggcatt tcctcaggga cccacagctc
       61 caccagccgg cccctcccag tgctggaata gacagttcct cagtccacat ctgccaaagg
      121 cggcactaga aggcatcctg ccttttttac tgcgttctgg aggtggggtc acaaagcact
      181 gctcactgca taaaagggac agcatcctgc ccctggcagc cctgcctgac cagctccgcc
      241 tctcccactg ctatccaacc tgtacaccct ggtgaccatg tccaggccag tggccttaag
      301 gactgtctct gtactgatgg ctccacatct acctctccag ccagactctc ctctgaactc
      361 gggcctcaca tggccaactg ctacttggaa caaatcgccc cttggctggc agatgtgtta
      421 acatgcccag accaagatcc caactcccac aacccaactc ccaggtcaga tggaacctct
      481 tcttcccagg cccttctgtt cctctcctca gcccctccca cctcccttca gaataagtct
      541 agactcttat cgctttcacc aagcctgcgc ccagcatccc tgcacaggga ttgttaggac
      601 agcctgacgc cctgcttcca ccctgcccca agatgccctg ctctgcag
//