LOCUS       AF029684                2268 bp    mRNA    linear   HUM 24-JUL-2016
DEFINITION  Homo sapiens IkB kinase-beta (IKK-beta) mRNA, partial cds.
ACCESSION   AF029684
VERSION     AF029684.1
KEYWORDS    .
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2268)
  AUTHORS   Woronicz,J.D., Gao,X., Cao,Z., Rothe,M. and Goeddel,D.V.
  TITLE     IkappaB kinase-beta: NF-kappaB activation and complex formation
            with IkappaB kinase-alpha and NIK
  JOURNAL   Science 278 (5339), 866-869 (1997)
   PUBMED   9346485
REFERENCE   2  (bases 1 to 2268)
  AUTHORS   Woronicz,J.D., Gao,X., Cao,Z., Rothe,M. and Goeddel,D.V.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-OCT-1997) Biology, Tularik, Inc., Two Corporate
            Drive, S. San Francisco, CA 94080, USA
FEATURES             Location/Qualifiers
     source          1..2268
                     /db_xref="H-InvDB:HIT000062986"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /cell_line="Jurkat"
                     /cell_type="T cell"
     gene            1..>2268
                     /gene="IKK-beta"
     CDS             1..>2268
                     /gene="IKK-beta"
                     /codon_start=1
                     /product="IkB kinase-beta"
                     /protein_id="AAC51860.1"
                     /translation="MSWSPSLTTQTCGAWEMKERLGTGGFGNVIRWHNQETGEQIAIK
                     QCRQELSPRNRERWCLEIQIMRRLTHPNVVAARDVPEGMQNLAPNDLPLLAMEYCQGG
                     DLRKYLNQFENCCGLREGAILTLLSDIASALRYLHENRIIHRDLKPENIVLQQGEQRL
                     IHKIIDLGYAKELDQGSLCTSFVGTLQYLAPELLEQQKYTVTVDYWSFGTLAFECITG
                     FRPFLPNWQPVQWHSKVRQKSEVDIVVSEDLNGTVKFSSSLPYPNNLNSVLAERLEKW
                     LQLMLMWHPRQRGTDPTYGPNGCFKALDDILNLKLVHILNMVTGTIHTYPVTEDESLQ
                     SLKARIQQDTGIPEEDQELLQEAGLALIPDKPATQCISDGKLNEGHTLDMDLVFLFDN
                     SKITYETQISPRPQPESVSCILQEPKRNLAFFQLRKVWGQVWHSIQTLKEDCNRLQQG
                     QRAAMMNLLRNNSCLSKMKNSMASMSQQLKAKLDFFKTSIQIDLEKYSEQTEFGITSD
                     KLLLAWREMEQAVELCGRENEVKLLVERMMALQTDIVDLQRSPMGRKQGGTLDDLEEQ
                     ARELYRRLREKPRDQRTEGDSQEMVRLLLQAIQSFEKKVRVIYTQLSKTVVCKQKALE
                     LLPKVEEVVSLMNEDEKTVVRLQEKRQKELWNLLKIACSKVRGPVSGSPDSMNASRLS
                     QPGQLMSQPSTASNSLPEPAKKSEELVAEAHNLCTLLENAIQDTVREQDQSFTALDWS
                     WLQTEEEEHSCLEQAS"
BASE COUNT          603 a          569 c          661 g          435 t
ORIGIN      
        1 atgagctggt caccttccct gacaacgcag acatgtgggg cctgggaaat gaaagagcgc
       61 cttgggacag ggggatttgg aaatgtcatc cgatggcaca atcaggaaac aggtgagcag
      121 attgccatca agcagtgccg gcaggagctc agcccccgga accgagagcg gtggtgcctg
      181 gagatccaga tcatgagaag gctgacccac cccaatgtgg tggctgcccg agatgtccct
      241 gaggggatgc agaacttggc gcccaatgac ctgcccctgc tggccatgga gtactgccaa
      301 ggaggagatc tccggaagta cctgaaccag tttgagaact gctgtggtct gcgggaaggt
      361 gccatcctca ccttgctgag tgacattgcc tctgcgctta gataccttca tgaaaacaga
      421 atcatccatc gggatctaaa gccagaaaac atcgtcctgc agcaaggaga acagaggtta
      481 atacacaaaa ttattgacct aggatatgcc aaggagctgg atcagggcag tctttgcaca
      541 tcattcgtgg ggaccctgca gtacctggcc ccagagctac tggagcagca gaagtacaca
      601 gtgaccgtcg actactggag cttcggcacc ctggcctttg agtgcatcac gggcttccgg
      661 cccttcctcc ccaactggca gcccgtgcag tggcattcaa aagtgcggca gaagagtgag
      721 gtggacattg ttgttagcga agacttgaat ggaacggtga agttttcaag ctctttaccc
      781 taccccaata atcttaacag tgtcctggct gagcgactgg agaagtggct gcaactgatg
      841 ctgatgtggc acccccgaca gaggggcacg gatcccacgt atgggcccaa tggctgcttc
      901 aaggccctgg atgacatctt aaacttaaag ctggttcata tcttgaacat ggtcacgggc
      961 accatccaca cctaccctgt gacagaggat gagagtctgc agagcttgaa ggccagaatc
     1021 caacaggaca cgggcatccc agaggaggac caggagctgc tgcaggaagc gggcctggcg
     1081 ttgatccccg ataagcctgc cactcagtgt atttcagacg gcaagttaaa tgagggccac
     1141 acattggaca tggatcttgt ttttctcttt gacaacagta aaatcaccta tgagactcag
     1201 atctccccac ggccccaacc tgaaagtgtc agctgtatcc ttcaagagcc caagaggaat
     1261 ctcgccttct tccagctgag gaaggtgtgg ggccaggtct ggcacagcat ccagaccctg
     1321 aaggaagatt gcaaccggct gcagcaggga cagcgagccg ccatgatgaa tctcctccga
     1381 aacaacagct gcctctccaa aatgaagaat tccatggctt ccatgtctca gcagctcaag
     1441 gccaagttgg atttcttcaa aaccagcatc cagattgacc tggagaagta cagcgagcaa
     1501 accgagtttg ggatcacatc agataaactg ctgctggcct ggagggaaat ggagcaggct
     1561 gtggagctct gtgggcggga gaacgaagtg aaactcctgg tagaacggat gatggctctg
     1621 cagaccgaca ttgtggactt acagaggagc cccatgggcc ggaagcaggg gggaacgctg
     1681 gacgacctag aggagcaagc aagggagctg tacaggagac taagggaaaa acctcgagac
     1741 cagcgaactg agggtgacag tcaggaaatg gtacggctgc tgcttcaggc aattcagagc
     1801 ttcgagaaga aagtgcgagt gatctatacg cagctcagta aaactgtggt ttgcaagcag
     1861 aaggcgctgg aactgttgcc caaggtggaa gaggtggtga gcttaatgaa tgaggatgag
     1921 aagactgttg tccggctgca ggagaagcgg cagaaggagc tctggaatct cctgaagatt
     1981 gcttgtagca aggtccgtgg tcctgtcagt ggaagcccgg atagcatgaa tgcctctcga
     2041 cttagccagc ctgggcagct gatgtctcag ccctccacgg cctccaacag cttacctgag
     2101 ccagccaaga agagtgaaga actggtggct gaagcacata acctctgcac cctgctagaa
     2161 aatgccatac aggacactgt gagggaacaa gaccagagtt tcacggccct agactggagc
     2221 tggttacaga cggaagaaga agagcacagc tgcctggagc aggcctca
//