LOCUS AB036063 4955 bp mRNA linear HUM 11-MAR-2000
DEFINITION Homo sapiens p53R2 mRNA for ribonucleotide reductase, complete cds.
ACCESSION AB036063
VERSION AB036063.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4955)
AUTHORS Tanaka,H., Arakawa,H. and Nakamura,Y.
TITLE Direct Submission
JOURNAL Submitted (18-DEC-1999) to the DDBJ/EMBL/GenBank databases.
Contact:Yusuke Nakamura
University of Tokyo, Institute of Medical Science, Human Genome
Center, Laboratory of Molecular Medicine; 4-6-1 Shirokanedai,
Minato-ku, Tokyo 108-8639, Japan
REFERENCE 2
AUTHORS Tanaka,H., Arakawa,H., Yamaguchi,T., Shiraishi,K., Fukuda,S.,
Matsui,K., Takei,Y. and Nakamura,Y.
TITLE A ribonucleotide reductase gene involved in a p53-dependent
cell-cycle checkpoint for DNA damage
JOURNAL Nature 404, 42-49 (2000)
COMMENT
FEATURES Location/Qualifiers
source 1..4955
/chromosome="8"
/db_xref="H-InvDB:HIT000059164"
/db_xref="taxon:9606"
/map="8q23.1"
/mol_type="mRNA"
/organism="Homo sapiens"
CDS 245..1300
/codon_start=1
/gene="p53R2"
/product="ribonucleotide reductase"
/protein_id="BAA92434.1"
/transl_table=1
/translation="MGDPERPEAAGLDQDERSSSDTNESEIKSNEEPLLRKSSRRFVI
FPIQYPDIWKMYKQAQASFWTAEEVDLSKDLPHWNKLKADEKYFISHILAFFAASDGI
VNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIRDPKKREFLFNAIE
TMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGVFFSGSFAAIFWLKKRGLMPGLT
FSNELISRDEGLHCDFACLMFQYLVNKPSEERVREIIVDAVKIEQEFLTEALPVGLIG
MNCILMKQYIEFVADRLLVELGFSKVFQAENPFDFMENISLEGKTNFFEKRVSEYQRF
AVMAETTDNVFTLDADF"
polyA_site 4933
/note="22 a nucleotides"
BASE COUNT 1526 a 803 c 999 g 1627 t
ORIGIN
1 ggctggccga agttaggcgg agccccgagg cgggggaggc ggggccgggc cggcgcaggg
61 agagtcactc aatggacagg cgagaaagca ggaccggcgc ggcggggcgg ggccggccga
121 gtccctagag ctgggggcgg ggcggaccca gcggaccagc ggaccacctg ggtgctgtcg
181 tagttggagg tggcctgagg agctcagttc cctcagcgcc cgtagcttcg gcggagtctg
241 cgcgatgggc gacccggaaa ggccggaagc ggccgggctg gatcaggatg agagatcatc
301 ttcagacacc aacgaaagtg aaataaagtc aaatgaagag ccactcctaa gaaagagttc
361 tcgccggttt gtcatctttc caatccagta ccctgatatt tggaaaatgt ataaacaggc
421 acaggcttcc ttctggacag cagaagaggt cgacttatca aaggatctcc ctcactggaa
481 caagcttaaa gcagatgaga agtacttcat ctctcacatc ttagcctttt ttgcagccag
541 tgatggaatt gtaaatgaaa atttggtgga gcgctttagt caggaggtgc aggttccaga
601 ggctcgctgt ttctatggct ttcaaattct catcgagaat gttcactcag agatgtacag
661 tttgctgata gacacttaca tcagagatcc caagaaaagg gaatttttat ttaatgcaat
721 tgaaaccatg ccctatgtta agaaaaaagc agattgggcc ttgcgatgga tagcagatag
781 aaaatctact tttggggaaa gagtggtggc ctttgctgct gtagaaggag ttttcttctc
841 aggatctttt gctgctatat tctggctaaa gaagagaggt cttatgccag gactcacttt
901 ttccaatgaa ctcatcagca gagatgaagg acttcactgt gactttgctt gcctgatgtt
961 ccaatactta gtaaataagc cttcagaaga aagggtcagg gagatcattg ttgatgctgt
1021 caaaattgag caggagtttt taacagaagc cttgccagtt ggcctcattg gaatgaattg
1081 cattttgatg aaacagtaca ttgagtttgt agctgacaga ttacttgtgg aacttggatt
1141 ctcaaaggtt tttcaggcag aaaatccttt tgattttatg gaaaacattt ctttagaagg
1201 aaaaacaaat ttctttgaga aacgagtttc agagtatcag cgttttgcag ttatggcaga
1261 aaccacagat aacgtcttca ccttggatgc agatttttaa aaaacctctc gttttaaaac
1321 tctataaact tgtcattggt aaatagtagt ctattttcct ctgcttaaaa aaaattttaa
1381 gtatatcctt taaaggactg ggggtttgct caaaaggaaa tccaaaacct attctaaaca
1441 atttgcattt atataatttt cctgtttaac aacaagagtg tgacctaaat gcttttgtct
1501 tgtcactgaa ataaaagatg gcattatgtg gttaagagca tggggcgagg ggtcagacat
1561 gagtctaagg ttctgccctt actccagtgt gtgacccttg gcaagtcagt taatcttggt
1621 aaacctcggt gtacttatct ttaaaatggg agtaatagta ggtcctaaat tcatagagtg
1681 gatattagga ttaggatgca aaaataaatg cttaaccaac actactactg ttagcaccac
1741 tactaattat cattcattga taatattaat tgcaatgatg ttgtaataaa atactctcat
1801 ttccttaaaa taattgtgat tctaggtcct aggatctaga attagatctt tgtattttta
1861 atgcttaggg gaagaatata agtatctcct taaaaagaac ataattctca ttcacgcaag
1921 aataagttct ttgaattcct tagtatgtag tgaagaaaat ttagttgtta gttgctttgg
1981 gaagcctact tatggagtgg aaaccaggag gttatcatgg tagttgacct tgtaagaaaa
2041 atgattcttc ttcagaaatt aaaaacataa ctattgccag atttagctct ggaatgttta
2101 gaatcaggct agaatagcat tttccaaaga atattctaag agctattagc tcctctagat
2161 attttgttgg gggaaaaagg ggattctgtg gtcagatgag tttgggaaat gctgaacact
2221 tcattcttct ttagcaagta cagtcagtac atcaaagact gagcagttca gtggtacata
2281 aatttatctc gccctgcata ttcccaacat acttaacaca gatgtttttt acctgttaac
2341 atctcaccca gctagtgttc ctcagaacaa agattggaaa aagctggccg agaaccattt
2401 atacatagag gaagggctta cggactgaga aagggagaac atggtaggga ttattgaatc
2461 atttcaaatt tataccaagc ctgaatagtg taccagcaat tgacttaggc tgtgtttctt
2521 tatggtttta aaactcttga gctgttataa gagatagttc ttttaatgtg actatgcaac
2581 atgatagcca atggtgaggg aaaaggaggt ttctctagaa gagtctgatg aaaggccggg
2641 aaccaaggtt tttgagaagt ctgcccctat ttatttttag taagtatcaa gaggtagcct
2701 gagcctagtt agagttagac ctgtctttgg atgaagaagt cttaatactg aaatactgaa
2761 tttttaatac attattattt ggtattctgt ataccccttc aagcagttgt ttcccattcc
2821 caacaaactg tactttatac aattctggat gctaaaactt agagattttc tctttgcata
2881 aattttggct ccattctttc cataacaatc taatcaaaac tgggagttct caagtgaatg
2941 caaaaggagc aggccataac tttatttgtt agagacactg tcagaaactt gagatctttt
3001 ggcctatgat aataccatta atttttgcat tgcttcagtt tgccaagtgt ttttacatca
3061 tctcatttga tctcaaaaca gcttgacaga gcaactgtta ttgaaatatt acagatggaa
3121 agaatgaggc tcagggaagt taaatgactt ggccaagatc tgctcatcgt cactgtctgt
3181 acagtatttt tttttagagg ttgtaatgtc tcagatttag tcctttacca tctatgttga
3241 tttgcttttg tctatttcct cattaattga atatacttta aatatatata ttaaagtatc
3301 aaaatataga gagacatttg aactgtattc aggtaatatg tttaaagata tttatatatt
3361 gccatacaaa aacttaacat ttaaaactga taatatctgt aatgacatca gaatgaaaga
3421 aaaaaaattg tacagtgtat attcctttgt tttgaatcca aatctttttc ataggtaatg
3481 acagatgcct taatgtgaag cttatttata atagcaataa acctaactgg atttggatga
3541 agaagtctta atactgacat actggatttt taatgcactg gtttgttatt tggtattcta
3601 tctctttttc caggcctcca ggttgcacat ttatttatta tgttcaatac tttggttctt
3661 agttcttaaa gaatcaagaa gttgtgtaat cttttaaaaa tattatcttg cagataaaga
3721 aaaaaattaa gagtgtgttt acaactgttt tctctttttt acagtacatg tatttaaatc
3781 attgctataa taaagttaag ttcattagga atataaaaac ttgcagttct atgatagatt
3841 gcatttatta aaaatgtttc attgtatcac atagaaatat ggccaggaag gacttgagaa
3901 gacagtttga tccattgctt ttagacagga ctgggttttg ctgtccaatt atatacaata
3961 atagtttttc ttacaactaa gctggcccca gccttgtctt gatattaata catgaaattt
4021 ttataattgt ctcattgtct catttagaaa catccatatt tttctgcttt ttctattgcc
4081 attttttatt tgtgcatgaa ttgattattg agaaaatgta gcagtttgca tatttaaaaa
4141 ttaatcattt tgcattttac atttaaatat gctaacatcg ctgtcataga attcccaaat
4201 ttcatttgta gatactgaac taagggctaa tgtcaggagc tgatttttaa tgataaagct
4261 gcagatgggc taaataaaag ccaaattaat cctacaatca ggtattatgt ttttaaacca
4321 agttgagtga attggtagtg gacttgggaa atcttcccca gcagaatctg gatgaatggc
4381 acagaattga aatctctttg tttcccacca tttcccttta agtgctctgc tcctttgtaa
4441 aaagttaaag atttgaaaga gaatctcata ttcccgaggc attaggaaga aaggatttaa
4501 tcccttcaat ttggggctta atcttgttta aaaaaatgta agtgaagatg gaaggctgga
4561 gagaatgatt gctttttgta cagttaaata aggtcacaat attcttacat actttgtttt
4621 acaactgtgt tttcattttt tcaaatgtct ggccatttag caaagttatt tactatttac
4681 tgtgtacata gaaaggttta ttatgtgtgg tgtatctaaa tttttttttg ctgaaataca
4741 ttatggtcaa tcaagccaag cctgcatgta cagaatttgt ttttttttca aataaattag
4801 ttgttttctt atttttttgg cttagtatgt tgaaataaac tatggtatct tcatcatttt
4861 gtacatttcc tttttgagga aggtttcttt ataagtgcaa gggctaccct aataaaggaa
4921 tgtatatact tacaaaaaaa aaaaaaaaaa aaaaa
//