LOCUS AF183909 12077 bp DNA linear INV 26-JUL-2016
DEFINITION Argopecten irradians MHC gene, alternatively spliced products:
myosin heavy chain, partial cds and catchin, complete cds.
ACCESSION AF183909
VERSION AF183909.1
KEYWORDS .
SOURCE Argopecten irradians (bay scallop)
ORGANISM Argopecten irradians
Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
Autobranchia; Pteriomorphia; Pectinida; Pectinoidea; Pectinidae;
Argopecten.
REFERENCE 1 (bases 1 to 12077)
AUTHORS Yamada,A., Yoshio,M., Oiwa,K. and Nyitray,L.
TITLE Catchin, a novel protein in molluscan catch muscles, is produced by
alternative splicing from the myosin heavy chain gene
JOURNAL J. Mol. Biol. 295 (2), 169-178 (2000)
PUBMED 10623517
REFERENCE 2 (bases 1 to 12077)
AUTHORS Nyitray,L., Jancso,A. and Szent-Gyorgyi,A.G.
TITLE Sequence analysis of the scallop muscle myosin heavy chain gene.
Two transcriptional units and at least five splicoforms
JOURNAL Unpublished
REFERENCE 3 (bases 1 to 12077)
AUTHORS Nyitray,L.
TITLE Direct Submission
JOURNAL Submitted (06-SEP-1999) Biochemistry, Eotvos University, Puskin U.
3., Budapest H-1088, Hungary
FEATURES Location/Qualifiers
source 1..12077
/organism="Argopecten irradians"
/mol_type="genomic DNA"
/db_xref="taxon:31199"
gene <1..12077
/gene="MHC"
/note="muscle myosin heavy chain"
mRNA join(<1..258,405..1080,1235..1380,1609..1699,4171..4227,
4686..4772,4930..5096,5293..5371,6624..6869,7050..7246,
7448..7580,7720..7936,8080..8320,8435..8627,8751..9452,
9592..9759,10399..10444,11331..12077)
/gene="MHC"
/product="myosin heavy chain striated muscle specific
isoform"
mRNA join(<1..258,405..1080,1235..1380,1609..1699,4171..4227,
4686..4772,4930..5096,5631..5709,6624..6869,7050..7246,
7448..7580,7720..7936,8080..8320,8435..8627,8751..9452,
9592..9759,9953..10054,11331..12077)
/gene="MHC"
/product="myosin heavy chain cardiac muscle specific
isoform 1"
mRNA join(<1..258,405..1080,1235..1380,1609..1699,4171..4227,
4686..4772,4930..5096,5631..5709,6624..6869,7050..7246,
7448..7580,7720..7936,8080..8320,8435..8627,8751..9452,
9592..9759,10275..10312,11331..12077)
/gene="MHC"
/product="myosin heavy chain catch (smooth) muscle
specific isoform"
mRNA join(<1..258,405..1080,1235..1380,1609..1699,4171..4227,
4686..4772,4930..5096,5631..5709,6624..6869,7050..7246,
7448..7580,7720..7936,8080..8320,8435..8627,8751..9452,
9592..9759,11331..12077)
/gene="MHC"
/product="myosin heavy chain cardiac muscle specific
isoform 2"
CDS join(<1..258,405..1080,1235..1380,1609..1699,4171..4227,
4686..4772,4930..5096,5631..5709,6624..6869,7050..7246,
7448..7580,7720..7936,8080..8320,8435..8627,8751..9452,
9592..9759,11331..11435)
/gene="MHC"
/note="exon22b alternatively spliced; exon-22 excluded"
/codon_start=2
/product="myosin heavy chain cardiac muscle specific
isoform 2"
/protein_id="AAF62395.1"
/translation="YSILAPNAIPQGFVDGKTVSEKILAGLQMDPAEYRLGTTKVFFK
AGVLGNLEEMRDERLSKIISMFQAHIRGYLIRKAYKKLQDQRIGLSVIQRNIRKWLVL
RNWQWWKLYSKVKPLLSIARQEEEMKEQLKQMDKMKEDLAKTERIKKELEEQNVTLLE
QKNDLFLQLQTLEDSMGDQEERVEKLIMQKADFESQIKELEERLLDEEDAAADLEGIK
KKMEADNANLKKDIGDLENTLQKAEQDKAHKDNQISTLQGEISQQDEHIGKLNKEKKA
LEEANKKTSDSLQAEEDKCNHLNKLKAKLEQALDELEDNLEREKKVRGDVEKAKRKVE
QDLKSTQENVEDLERVKRELEENVRRKEAEISSLNSKLEDEQNLVSQLQRKIKELQAR
IEELEEELEAERNARAKVEKQRAELNRELEELGERLDEAGGATSAQIELNKKREAELL
KIRRDLEEASLQHEAQISALRKKHQDAANEMADQVDQLQKVKSKSEKEKQQLRSEVED
LQAQIQHISKNKGCSEKVMKQFESQMSDLNARLEDSQRSINELQSQKSRLQAENSDLT
RQLEDAEHRVSVLSKEKSQLSSQLEDARRSLEEETRARSKLQNEVRNMHADMDAIREQ
LEEEQESKSDVQRQLSKANNEIQQWRSKFESEGANRTEELEDQKRKLLGKLSEAEQTT
EAANAKCSALEKAKSRLQQELEDMSIEVDRANASVNQMEKKQRAFDKTTAEWQAKVNS
LQSELENSQKESRGYSAELYRIKASIEEYQDSIGALRRENKNLADEIHDLTDQLSEGG
RSTHELDKARRRLEMEKEELQAALEEAEGALEQEEAKVMRAQLEIATVRNEIDKRIQE
KEEEFDNTRRNHQRALESMQASLEAEAKGKADAMRIKKKLEQDINELEVALDASNRGK
AEMEKTVKRYQQQIREMQTSIEEEQRQRDEARESYNMAERRCTLMSGEVEELRAALEQ
AERARKASDNELADANDRVNELTSQVSSVQGQKRKLEGDINAMQTDLDEMHGELKGAD
ERCKKAMADAARLADELRAEQDHSNQVEKVRKNLESQVKEFQIRLDEAEASSLKGGKK
MIQKLESRVHELEAELDNEQRRHAETQKNMRKADRRLKELAFQADEDRKNQERLQELI
DKLNAKIKTFKRQVEEAEEIAAINLAKYRKAQHELEEAEERADTADSTLQKFRAKSRS
SVSVQRSSVSVSASNSPSYSYLSPRTRGSSVVNSYRSVTPSNEGDDDGY"
CDS join(<1..258,405..1080,1235..1380,1609..1699,4171..4227,
4686..4772,4930..5096,5293..5371,6624..6869,7050..7246,
7448..7580,7720..7936,8080..8320,8435..8627,8751..9452,
9592..9759,10399..10401)
/gene="MHC"
/note="exon22a and exon31cb; alternatively spliced;
similar to Genbank Accession number X55714"
/codon_start=2
/product="myosin heavy chain striated muscle specific
isoform"
/protein_id="AAF62391.1"
/translation="YSILAPNAIPQGFVDGKTVSEKILAGLQMDPAEYRLGTTKVFFK
AGVLGNLEEMRDERLSKIISMFQAHIRGYLIRKAYKKLQDQRIGLSVIQRNIRKWLVL
RNWQWWKLYSKVKPLLSIARQEEEMKEQLKQMDKMKEDLAKTERIKKELEEQNVTLLE
QKNDLFLQLQTLEDSMGDQEERVEKLIMQKADFESQIKELEERLLDEEDAAADLEGIK
KKMEADNANLKKDIGDLENTLQKAEQDKAHKDNQISTLQGEISQQDEHIGKLNKEKKA
LEEANKKTSDSLQAEEDKCNHLNKLKAKLEQALDELEDNLEREKKVRGDVEKAKRKVE
QDLKSTQENVEDLERVKRELEENVRRKEAEISSLNSKLEDEQNLVSQLQRKIKELQAR
IEELEEELEAERNARAKVEKQRAELNRELEELGERLDEAGGATSAQIELNKKREAELL
KIRRDLEEASLQHEAQISALRKKHQDAANEMADQVDQLQKVKSKLEKDKKDLKREMDD
LESQMTHNMKNKGCSEKVMKQFESQMSDLNARLEDSQRSINELQSQKSRLQAENSDLT
RQLEDAEHRVSVLSKEKSQLSSQLEDARRSLEEETRARSKLQNEVRNMHADMDAIREQ
LEEEQESKSDVQRQLSKANNEIQQWRSKFESEGANRTEELEDQKRKLLGKLSEAEQTT
EAANAKCSALEKAKSRLQQELEDMSIEVDRANASVNQMEKKQRAFDKTTAEWQAKVNS
LQSELENSQKESRGYSAELYRIKASIEEYQDSIGALRRENKNLADEIHDLTDQLSEGG
RSTHELDKARRRLEMEKEELQAALEEAEGALEQEEAKVMRAQLEIATVRNEIDKRIQE
KEEEFDNTRRNHQRALESMQASLEAEAKGKADAMRIKKKLEQDINELEVALDASNRGK
AEMEKTVKRYQQQIREMQTSIEEEQRQRDEARESYNMAERRCTLMSGEVEELRAALEQ
AERARKASDNELADANDRVNELTSQVSSVQGQKRKLEGDINAMQTDLDEMHGELKGAD
ERCKKAMADAARLADELRAEQDHSNQVEKVRKNLESQVKEFQIRLDEAEASSLKGGKK
MIQKLESRVHELEAELDNEQRRHAETQKNMRKADRRLKELAFQADEDRKNQERLQELI
DKLNAKIKTFKRQVEEAEEIAAINLAKYRKAQHELEEAEERADTADSTLQKFRAKSRS
SVSVQRSSVSVSASN"
CDS join(<1..258,405..1080,1235..1380,1609..1699,4171..4227,
4686..4772,4930..5096,5631..5709,6624..6869,7050..7246,
7448..7580,7720..7936,8080..8320,8435..8627,8751..9452,
9592..9759,10275..10307)
/gene="MHC"
/note="exon22b and exon31b; alternatively spliced; similar
to Genbank Accession number U09782"
/codon_start=2
/product="myosin heavy chain catch (smooth) muscle
specific isoform"
/protein_id="AAF62392.1"
/translation="YSILAPNAIPQGFVDGKTVSEKILAGLQMDPAEYRLGTTKVFFK
AGVLGNLEEMRDERLSKIISMFQAHIRGYLIRKAYKKLQDQRIGLSVIQRNIRKWLVL
RNWQWWKLYSKVKPLLSIARQEEEMKEQLKQMDKMKEDLAKTERIKKELEEQNVTLLE
QKNDLFLQLQTLEDSMGDQEERVEKLIMQKADFESQIKELEERLLDEEDAAADLEGIK
KKMEADNANLKKDIGDLENTLQKAEQDKAHKDNQISTLQGEISQQDEHIGKLNKEKKA
LEEANKKTSDSLQAEEDKCNHLNKLKAKLEQALDELEDNLEREKKVRGDVEKAKRKVE
QDLKSTQENVEDLERVKRELEENVRRKEAEISSLNSKLEDEQNLVSQLQRKIKELQAR
IEELEEELEAERNARAKVEKQRAELNRELEELGERLDEAGGATSAQIELNKKREAELL
KIRRDLEEASLQHEAQISALRKKHQDAANEMADQVDQLQKVKSKSEKEKQQLRSEVED
LQAQIQHISKNKGCSEKVMKQFESQMSDLNARLEDSQRSINELQSQKSRLQAENSDLT
RQLEDAEHRVSVLSKEKSQLSSQLEDARRSLEEETRARSKLQNEVRNMHADMDAIREQ
LEEEQESKSDVQRQLSKANNEIQQWRSKFESEGANRTEELEDQKRKLLGKLSEAEQTT
EAANAKCSALEKAKSRLQQELEDMSIEVDRANASVNQMEKKQRAFDKTTAEWQAKVNS
LQSELENSQKESRGYSAELYRIKASIEEYQDSIGALRRENKNLADEIHDLTDQLSEGG
RSTHELDKARRRLEMEKEELQAALEEAEGALEQEEAKVMRAQLEIATVRNEIDKRIQE
KEEEFDNTRRNHQRALESMQASLEAEAKGKADAMRIKKKLEQDINELEVALDASNRGK
AEMEKTVKRYQQQIREMQTSIEEEQRQRDEARESYNMAERRCTLMSGEVEELRAALEQ
AERARKASDNELADANDRVNELTSQVSSVQGQKRKLEGDINAMQTDLDEMHGELKGAD
ERCKKAMADAARLADELRAEQDHSNQVEKVRKNLESQVKEFQIRLDEAEASSLKGGKK
MIQKLESRVHELEAELDNEQRRHAETQKNMRKADRRLKELAFQADEDRKNQERLQELI
DKLNAKIKTFKRQVEEAEEIAAINLAKYRKAQHELEEAEERADTADSTLQKFRAKSRS
SVSVQRSSVSVSASNAAHVAHHHVE"
CDS join(<1..258,405..1080,1235..1380,1609..1699,4171..4227,
4686..4772,4930..5096,5631..5709,6624..6869,7050..7246,
7448..7580,7720..7936,8080..8320,8435..8627,8751..9452,
9592..9759,9953..10027)
/gene="MHC"
/note="exon22b and exon31a; alternatively spliced"
/codon_start=2
/product="myosin heavy chain cardiac muscle specific
isoform 1"
/protein_id="AAF62394.1"
/translation="YSILAPNAIPQGFVDGKTVSEKILAGLQMDPAEYRLGTTKVFFK
AGVLGNLEEMRDERLSKIISMFQAHIRGYLIRKAYKKLQDQRIGLSVIQRNIRKWLVL
RNWQWWKLYSKVKPLLSIARQEEEMKEQLKQMDKMKEDLAKTERIKKELEEQNVTLLE
QKNDLFLQLQTLEDSMGDQEERVEKLIMQKADFESQIKELEERLLDEEDAAADLEGIK
KKMEADNANLKKDIGDLENTLQKAEQDKAHKDNQISTLQGEISQQDEHIGKLNKEKKA
LEEANKKTSDSLQAEEDKCNHLNKLKAKLEQALDELEDNLEREKKVRGDVEKAKRKVE
QDLKSTQENVEDLERVKRELEENVRRKEAEISSLNSKLEDEQNLVSQLQRKIKELQAR
IEELEEELEAERNARAKVEKQRAELNRELEELGERLDEAGGATSAQIELNKKREAELL
KIRRDLEEASLQHEAQISALRKKHQDAANEMADQVDQLQKVKSKSEKEKQQLRSEVED
LQAQIQHISKNKGCSEKVMKQFESQMSDLNARLEDSQRSINELQSQKSRLQAENSDLT
RQLEDAEHRVSVLSKEKSQLSSQLEDARRSLEEETRARSKLQNEVRNMHADMDAIREQ
LEEEQESKSDVQRQLSKANNEIQQWRSKFESEGANRTEELEDQKRKLLGKLSEAEQTT
EAANAKCSALEKAKSRLQQELEDMSIEVDRANASVNQMEKKQRAFDKTTAEWQAKVNS
LQSELENSQKESRGYSAELYRIKASIEEYQDSIGALRRENKNLADEIHDLTDQLSEGG
RSTHELDKARRRLEMEKEELQAALEEAEGALEQEEAKVMRAQLEIATVRNEIDKRIQE
KEEEFDNTRRNHQRALESMQASLEAEAKGKADAMRIKKKLEQDINELEVALDASNRGK
AEMEKTVKRYQQQIREMQTSIEEEQRQRDEARESYNMAERRCTLMSGEVEELRAALEQ
AERARKASDNELADANDRVNELTSQVSSVQGQKRKLEGDINAMQTDLDEMHGELKGAD
ERCKKAMADAARLADELRAEQDHSNQVEKVRKNLESQVKEFQIRLDEAEASSLKGGKK
MIQKLESRVHELEAELDNEQRRHAETQKNMRKADRRLKELAFQADEDRKNQERLQELI
DKLNAKIKTFKRQVEEAEEIAAINLAKYRKAQHELEEAEERADTADSTLQKFRAKSRS
SVSVQRSSVSVSASNPGMLSTANLVGRGVSTQREPSTAK"
mRNA join(<2757..3224,4171..4227,4686..4772,4930..5096,
5631..5709,6624..6869,7050..7246,7448..7580,7720..7936,
8080..8320,8435..8627,8751..9452,9592..9759,10275..10312,
11331..12077)
/gene="MHC"
/product="catchin"
CDS join(2757..3224,4171..4227,4686..4772,4930..5096,
5631..5709,6624..6869,7050..7246,7448..7580,7720..7936,
8080..8320,8435..8627,8751..9452,9592..9759,10275..10307)
/gene="MHC"
/note="catch muscle specific myosin rod protein; unique
first exon, exon22b and exon32b; alternative transcription
unit; alternatively spliced"
/codon_start=1
/product="catchin"
/protein_id="AAF62393.1"
/translation="MSDGEQLKVEFSSSVVETSKDESPQPPPLDTPSPQAASVIEVKS
QVKATSNPAPKSEIAPAETRKTTTTTTTSSKKSTKSSTSRSSGYSDYLGDISRDYRGV
SPAVIESIATHPVLFSRSYQYEPRSTRISARSKRVLREASDLSLTSPGLKGLLEARIE
ELEEELEAERNARAKVEKQRAELNRELEELGERLDEAGGATSAQIELNKKREAELLKI
RRDLEEASLQHEAQISALRKKHQDAANEMADQVDQLQKVKSKSEKEKQQLRSEVEDLQ
AQIQHISKNKGCSEKVMKQFESQMSDLNARLEDSQRSINELQSQKSRLQAENSDLTRQ
LEDAEHRVSVLSKEKSQLSSQLEDARRSLEEETRARSKLQNEVRNMHADMDAIREQLE
EEQESKSDVQRQLSKANNEIQQWRSKFESEGANRTEELEDQKRKLLGKLSEAEQTTEA
ANAKCSALEKAKSRLQQELEDMSIEVDRANASVNQMEKKQRAFDKTTAEWQAKVNSLQ
SELENSQKESRGYSAELYRIKASIEEYQDSIGALRRENKNLADEIHDLTDQLSEGGRS
THELDKARRRLEMEKEELQAALEEAEGALEQEEAKVMRAQLEIATVRNEIDKRIQEKE
EEFDNTRRNHQRALESMQASLEAEAKGKADAMRIKKKLEQDINELEVALDASNRGKAE
MEKTVKRYQQQIREMQTSIEEEQRQRDEARESYNMAERRCTLMSGEVEELRAALEQAE
RARKASDNELADANDRVNELTSQVSSVQGQKRKLEGDINAMQTDLDEMHGELKGADER
CKKAMADAARLADELRAEQDHSNQVEKVRKNLESQVKEFQIRLDEAEASSLKGGKKMI
QKLESRVHELEAELDNEQRRHAETQKNMRKADRRLKELAFQADEDRKNQERLQELIDK
LNAKIKTFKRQVEEAEEIAAINLAKYRKAQHELEEAEERADTADSTLQKFRAKSRSSV
SVQRSSVSVSASNAAHVAHHHVE"
BASE COUNT 3726 a 2393 c 2435 g 3523 t
ORIGIN
1 atacagtatc ttggccccca acgccatccc acaaggattc gttgatggca agaccgtctc
61 cgagaagatt cttgctggac tccagatgga tcccgctgaa taccgtcttg gtaccaccaa
121 ggtattcttc aaggccggtg tcctcggtaa ccttgaggaa atgcgtgacg agcgtctttc
181 caagatcatc tccatgttcc aggcccacat ccgtggttac ctcatccgta aggcatacaa
241 gaaactccag gaccagaggt tagcatactt agtttttgat ttgatattat ttttaatgca
301 atctttaaaa tagaaactac attaataaat taacattatg tttatttaat aattatttaa
361 gaactttacg gaatcttaat taaacctcat cttttgtatt tcaggattgg tctctccgtg
421 atccagcgta acatcaggaa atggttggtt ctccgcaact ggcagtggtg gaaactctac
481 tccaaggtca agcctctcct cagcatcgcc cgtcaagagg aggaaatgaa ggaacagctc
541 aaacagatgg acaagatgaa ggaagatctt gccaagaccg agcgcatcaa gaaggaactt
601 gaggaacaga atgtcaccct tttggaacag aagaatgacc tcttccttca gctccagacc
661 cttgaggact ccatgggaga ccaggaagag cgtgttgaga aactcattat gcagaaggct
721 gacttcgagt ctcagatcaa ggaactcgag gagcgtctct tggacgagga agatgccgct
781 gccgatcttg agggcatcaa gaagaagatg gaagctgata acgccaacct caagaaggac
841 attggtgatc ttgagaacac cctccagaag gccgagcaag acaaagccca caaggacaac
901 cagatctcca ccctccaggg agagatttcc cagcaggatg agcacattgg caagctcaac
961 aaggaaaaga aggctcttga ggaggccaac aagaagacct ctgattctct ccaggctgag
1021 gaggacaagt gcaaccacct caacaaactg aaggccaagc ttgaacaggc tcttgacgag
1081 gtaaataaag ttaacaaatg taatatttta ttagtcttgt aaatgttctg aaaaattaat
1141 tcgagagacc taattataaa atgattttat ataagcgact ttattgatat agtaattaac
1201 acaagtgttg attgaatgat ttatttttat ttagcttgaa gacaaccttg agcgcgagaa
1261 gaaggtccgt ggtgatgttg agaaggccaa gaggaaggtc gaacaggacc tcaaatccac
1321 acaggagaac gttgaggatc ttgagcgcgt caagagggaa ctcgaggaga acgtcaggag
1381 gtaagaatcg atatcacaat agtttatagt tacattacat atagctatat atagacaaat
1441 atatcaaatt gtcattatag aagaaaattc agtataaata tatgtaaatt catattcaat
1501 gatattgtta tatttcttct aaagtcaaaa ttcattaata aatatagcag ttagttagaa
1561 ctaatgaaga acatatatat ataatatata tttatttctc gattacagga aggaagctga
1621 gatcagcagc ttgaactcca agctcgagga tgaacagaac cttgtcagcc agctccagag
1681 gaagatcaag gaactccagg tatgttgata cattatattt aaaaaaacaa cttttgtttg
1741 cacttgcacc agtagtataa ctgtcggaaa agttttggga cggtatcaga tataagggcc
1801 tatcatcatc tacactaata agagttatta ggacctgttg agggtgttat ctagaacact
1861 taatgaagat taaatcgcag gcgaaagcag tgtaatggtc tggggagtct tacacatgtt
1921 gcacaacatg atcacaagaa tctgtggtat gcggaagaac ggtagctctg tctgatgttg
1981 attcgctata aaagggaagg cacttcataa cgaccaatca gggccttagc tgtaacggga
2041 tagcagtgca cgtgtgtgta gtgttgttat ttccacagca gtgaagataa gcaatttgat
2101 gcacgcattc caacaccccc cgcctttatc ataatcagtt gtcttcttcg ttgatggttt
2161 ttatatgtgg tattttatca cgacataatc tcagtctaac ccccgtcctg gcctctagct
2221 aaataagaca atagtagttg tgcgactgtt gatgtacgtg gttctgtggc gataggtata
2281 tagctgtcgg tgtacatcac cattcgttag gtagcgtaga cactacaagg taggcactct
2341 actggtagcc atggagacag aattgatcat actacctcag cacatagttg gctgatgagc
2401 atcgtccttt aaaggctgac ggtgtgttac atcttccagt cgtgtcttgt cttagcttct
2461 atccacacgt ctctagagga ggttgttggg tcgtttcgtg ttgatacagg aagtcggctt
2521 ccaatgtcaa ggaacttggg ctgctattat ctgatgtact taaactggat cgtcaacaac
2581 cctaaactgt gtacactttg acttagtcct cttggagttg aacttgtctt ggctattcga
2641 cataggcatt cagtctttgg atttagattt gaggtgtctt tgtgatttta cacttgagtg
2701 cagatagacc ttccgggatt tttttcgttt gaagtatctc tgattaatca atcactatgt
2761 ctgacgggga acaacttaaa gtggaatttt cgagtagtgt agttgagacc agtaaagatg
2821 aaagccctca acctccacct ttagatactc cgtctccaca ggcggcttct gttattgaag
2881 tgaaatcaca agtgaaggca acatctaacc ctgctcctaa atcagaaatt gcccctgctg
2941 aaacacggaa aacaacaaca acaacgacaa catcatcaaa gaaatctaca aaatcttcta
3001 cttctagatc ttctggatat agtgattact taggggatat ctctcgtgat tatagaggag
3061 ttagtcctgc agttatagaa agcattgcta cacatccagt tttattctct cggtcttacc
3121 aatatgagcc gagatctacc agaattagtg ctagaagtaa gcgagtatta cgggaagcgt
3181 cggatctgtc gttaacatct ccgggcctaa agggtttgct tgaagtacag tatcaacatt
3241 ttccaattct ggctgctgta gatgcgaaat attgcttaac gtaattgctc tttgtgtaac
3301 tgttggcttt tcgctctcta tgctactggt gcaattgtag caatttagat gcactgatag
3361 caatattcgt cgcttacact aagctcagga tgccacagtg cgctaatgga atgtattgtt
3421 cgctctaagg taaaattatg atgtatttct attatatgtt atatttcttg ctatgcttat
3481 atttttatta tttgttttgt tctggagtta gtaaagctaa gttcagaaat atttccggta
3541 attgttgcta catttatttc tccatagtaa agtattctaa agctctatct cgctctgctc
3601 taaccaaaac aataaaatgc atgcacttgc aattcgcttt cactgtatgt atccgtaaaa
3661 gtatacgacc tttattttca cttaggcatc tggatgtcta tttttaacat ttctctggta
3721 tgttctgtag aacagcagac cttagtaatt caatccatcc cagcagcctg ataacgcctc
3781 tgtaaaacta gattgaaaca atttcaactt gtgtagtagc taagtttgtg ggagtttctg
3841 ttatctgtct gtgtgcaaat gcgtcatctg attttctcag cgatgttcag acgaaacttc
3901 acttactatt actcatagcg gaagtatgca ctcgctaagg tgctctttac gtacagacca
3961 atcagagatt taagaggcga tgaagtgcca gcacccttca tagctatctc aactctccct
4021 cgtcctggta gtgtcttgtt ttcctctgtt gtttccccat gtttcccctt ctgttatcct
4081 aaagtaactt aatcctttgt tagtaaggaa ataattttcg tattaaaata cttggacatt
4141 ctcacaaaca tggctgttga aaaatttcag gccaggatcg aagagttgga agaggaactc
4201 gaagccgaga ggaacgccag ggctaaggta agccattaat tgtcttgtaa atatttgtta
4261 tgtcatacac acatgattgt ataatggaaa cattagttat taatgatgca aagaatgaaa
4321 ctttaagatg gaactgaacg tattatacct tgagtgatac aaataaaata tatttagtaa
4381 aagtaaccca ttttattgct gaataaaggt tttataaact tggcataact cagtatctaa
4441 atatagtata ttgatcgggc gaaactgcta gcagctgcct acaacgatgc gatgatggtg
4501 tcaagttact ttgatggtat aggcttatct ctgtccatct ctacttaaga ttttaacatt
4561 cagtctcagc gggaaacact ccacacacat atctagctgc attttccagt cccgtattac
4621 aaagaatgtt gaatattatt gtaccattaa ctggttttga agagatatct tccttggatt
4681 aacaggttga gaagcagcgt gctgaactta accgtgaatt ggaagaactc ggtgagcgtc
4741 ttgatgaggc tggtggtgcc acatctgccc aggtaagaca ctttgtatac aaacctgaga
4801 tgtcgtgatt aaaaagttcg cgtgatattc ataaaacaaa aacaattgtt tgagaatatg
4861 tttgccattt tcaactttac gcttctttct agcaatgaaa tctaattgat agcattatac
4921 tatgaacaga ttgagctcaa caagaagaga gaggctgagc ttcttaagat ccgccgtgat
4981 cttgaggagg cttccctcca gcacgaggcc cagatctctg ccctccgcaa gaagcaccag
5041 gatgccgcca acgagatggc cgaccaggtt gaccagctcc agaaagtcaa atccaagtaa
5101 gttattctca attatcaata tacattaccc tagctgcaaa agtatattca ggattgaaaa
5161 tatgctcaca gaaaattgat ataatttgca aactgctttg gagcagattg attaaatata
5221 actcgattaa gtcgtattat atggatgtga tagcagttgt ataccaaatt aaataattat
5281 aacaaattcc aggctcgaga aggacaagaa agatcttaag cgcgaaatgg atgacctcga
5341 gagtcagatg actcacaaca tgaagaacaa ggtatcacat gcctggtcat tacaccaagc
5401 atgtcataac gacagcacag tcctttacga tgatccatcc gtccttatat taccgagcat
5461 gtatcgaaca gggcacctcc tgtttggtca atccgtatac ctatccttag atattccgaa
5521 aagacacatt ccgttcccga gataatcagg atgtggatag tccaaccttt ttattttgta
5581 ttgtactttc ctgtgtgata ttgtgcattg tccccttaaa cccgtttcag gtccgagaaa
5641 gagaaacaac agttgagaag cgaggttgag gatttacaag ctcaaatcca acatatttct
5701 aagaataagg tagataggta gtcattctga aatttgcatg tgccatcaaa ttatttactt
5761 tatttaatta tttatggcgg catgttttca agctgatttt tactttatca gattatctag
5821 tattacgaca taggaccgtt tttcaggaaa tgcatgacga aaacacctaa attctaaatt
5881 gcatgtgaca tttccctcat atcaaccaga tcagaaaagg acaaacgaga cttgatggta
5941 gaatgtgaag acttgctcat gtgtttggaa caagccgaaa gagctagggt aaaacgtgtg
6001 gagatatatt aacaatttca gtgatagaat taacaacgaa ataacataaa ttcagattat
6061 cagataacaa aattgctttt ttttattaac atgacaacat tttttggctt tttgttaata
6121 atgttttgta aagttttatc actttttgtt taaattcact tagatacaat tgctttattt
6181 tcatcacact tgtacttgca tgtatttact tcatctccag tttttcagag tatgaatcac
6241 catttcacta accgaatcca tatcacgact actaatactg ttcaatgttg ttttgaaacc
6301 ggttataaaa acatctgtac ttgatttgtt tggaataaac tacaattata taactaccaa
6361 atgtaagtgt tcagctgttc tacagttgga cgtgaaatta tgtaaaagtg cttttctatt
6421 tattaatgtt aaaataattc gaagtaaacg aaccatccct cacatcagcc aacgagttaa
6481 tacatatcag gaggacctag tccgaaagcg ttaactaacc atatgtacat tgagcggctg
6541 ttacaactca acagttgaca aattactctt ctcaaacata tatacctcgc cttcttacta
6601 ttttgccgta aactttatca cagggatgct ccgagaaggt catgaagcag ttcgaatccc
6661 agatgtccga tttgaatgcc agactcgagg acagccagag gtccatcaac gagctccaga
6721 gccagaagag ccgtctccag gctgagaact ccgaccttac cagacagctc gaggatgctg
6781 aacaccgcgt cagcgttctc tccaaggaga aatctcagct ctcatcccag cttgaggatg
6841 cccgtcgcag ccttgaggag gagaccaggg taagttgtct tttattgtca ccaaatacct
6901 ttaacaatga aaacagaatc gttcaattta caaatttctg tatagatgga ccaatgtgaa
6961 gcaatgtata acagtgttta atatttgttg acatttaaat tgtaaacact tatcatcgta
7021 tagttacaca tgttaacttt tatgtttagg cccgcagcaa gctccagaat gaggtccgca
7081 acatgcacgc cgatatggat gctattcgtg aacagcttga ggaggaacag gaatccaaat
7141 ctgatgttca gcgccagctt tcaaaggcca acaacgagat ccagcaatgg aggtccaaat
7201 tcgagagcga gggtgctaac cgcactgagg agcttgagga ccagaagtat tgtattatac
7261 aatcacaaat aatactcaaa ttctaataac tctaatgaaa tggcaaaaga cgaaattgta
7321 ttgtatccaa aaacaggtcg acataagata aatggatatt tccacccgtt gttaaaacct
7381 ttaatgctat tggttgtaaa gtttcatttt gatatgcaga aatatattta cttttactta
7441 tatacaggcg caaacttctc ggcaagcttt ctgaggctga acagaccacc gaggctgcca
7501 acgccaaatg cagcgccttg gagaaggcca agtcccgcct gcagcaggag ttggaagaca
7561 tgtccattga agttgacagg gtatgtatat tacttaacga ttaaatgaat acagctataa
7621 ctttgatgat tattacacct tcataagaaa catacaactc ttatttaaac ctcatcattt
7681 ctaatagaaa ggaaatactt attccgtggt ttgttttagg ctaacgccag tgtcaaccag
7741 atggagaaga aacagcgtgc tttcgataag accaccgctg aatggcaagc caaggtcaac
7801 agcctccagt ccgagctcga gaactcccag aaggaatccc gcggctactc tgctgagctg
7861 tacaggatca aggccagcat tgaggaatac caagacagca ttggtgccct caggagggag
7921 aacaagaact tggctggtga ggacaattga attcacctta tatcaacgac tgattaatac
7981 atatccgtag tcatctcgct atgaaactaa attatcaatt atacttaata agttggaaat
8041 atagtttcaa attattaata tggaatttgt ttgttataga tgaaatccac gaccttactg
8101 atcagctgtc cgagggaggc cgctccacac acgagctcga caaagcccgc aggaggctcg
8161 agatggaaaa agaggaactc caggccgctc ttgaggaggc cgagggtgct cttgaacagg
8221 aggaagccaa ggtcatgcgt gctcagctcg agatcgccac cgtccgcaac gagatcgaca
8281 aacgcatcca ggagaaggaa gaggaattcg acaacacccg gtaaataaat atttcatcat
8341 atctctgtct tatgacatca aaattaaagt cgaacattac ttctcttctc acaaacagtg
8401 acagtcgaat ttacttttaa cttttatgtt acagccgcaa ccaccagcgt gcccttgaat
8461 ccatgcaggc cagtttggag gctgaggcca agggtaaggc tgatgccatg aggatcaaga
8521 agaagcttga acaggacatc aacgagctcg aggttgctct cgatgcttcc aacagaggca
8581 aggccgagat ggagaagacc gtcaagagat accagcaaca gatcagggta aataattata
8641 ttatagcgcc ctcaaaattc aaacggactt tcaattatga tattatctga attccgactg
8701 caatatatta gacatgcaaa agtttctaag tgttaaatta tatgattcag gaaatgcaga
8761 catccattga ggaggaacag agacagcgcg atgaggctcg cgaatcctac aacatggctg
8821 agaggaggtg cactcttatg tctggtgagg tcgaggagct cagagctgcc ttggaacagg
8881 ccgagagggc ccgcaaggca tctgacaatg agcttgctga tgccaacgac cgtgtcaatg
8941 aactcacatc tcaggtttca tctgtccagg gccagaagag gaaactcgag ggtgatatca
9001 atgccatgca gaccgacctt gatgagatgc acggcgagtt gaagggtgct gatgagaggt
9061 gcaagaaggc tatggctgat gccgctcgtc ttgctgatga actccgtgcc gaacaggatc
9121 acagcaacca ggttgagaag gtacgcaaga acttggaaag ccaggtcaag gaattccaga
9181 tccgtttgga tgaggctgag gcttcttccc tcaagggagg caagaagatg atccagaaat
9241 tggaatccag agtacatgag cttgaggctg aacttgacaa cgagcagcgc cgtcacgctg
9301 agacccagaa gaacatgcgc aaggccgacc gccgtcttaa ggaattggct ttccaggccg
9361 atgaggacag gaagaaccag gaacgtctcc aggaactcat tgacaaactc aacgccaaga
9421 tcaagacatt caagcgtcag gtcgaggaag ccgtaagtat tcgtttctat tgataggaca
9481 ttattctgta ttcattcaaa attcaaaaga tttaacggac gcgtgaaata tatcccatat
9541 ctctaaaaat ctaaaaatac ttgcattaaa ttttctaatt ggtctttaca ggaggagatc
9601 gcagccatca acttggccaa ataccgcaaa gcccagcacg agcttgagga ggctgaggaa
9661 cgcgctgaca ccgccgactc taccctccag aagttccgcg ccaagagccg tagctccgtc
9721 tctgtccagc gctccagcgt atccgttagt gcttctaacg taagtattat ataactttca
9781 cttgaaatga tattaatcga gaaatgtgcc gaacatgttg tttctgtata gaaataatga
9841 agtaagaaaa gaaagagaaa actttatata tatcaaatag attaaaaaat tgaattcata
9901 tgttatcgca cgattttctc tagattatta gctttctgta tatttatcac agccggggat
9961 gctgagtacg gccaatcttg ttggtcgtgg agttagtact cagagagaac catcaaccgc
10021 caaatagtaa actttgccac aataccaata ggaggtaaac cagaaagtgt ggcactaggt
10081 agttagtggt attccttgta gaaacatatt acagaatctt atatatctag tagtctgtag
10141 taatcattag tcattcacaa actacttacg accgttttga aatatagtta caatagttaa
10201 gtaaaccaat actaaggttt ttctagttta gaatttatct aatttgccct taatcgttcc
10261 ctgaaaactt gcaggccgca catgtcgcac atcaccacgt tgaatagaca ccgtaagttt
10321 cttcgagagt tgagctattt attgctactg tgctgctggt tctatggttg gctacatttt
10381 attgctattg tttttcagta aacatcttac gaagtttaca accgatatta gtaatacaca
10441 atcagtaagt cacgaagcat gggtcgagtg aagtaccctc ttcctgtatt tagtttctcg
10501 tgacattttt gtatttttcg tgttcatctt ccacccaaag ttaaatattg ttttcaatat
10561 ccacaaatcc agacaccctc cataaaaatc aagcaaacga acgaattcct tcttgaatat
10621 gccccatcca gtgcatgacg agccatacat cttggcctac cagatatttc ggaccaatcg
10681 gatgtgatcc tttcctcata atcatttaac acaaatcatc acatgcctaa tatattttca
10741 ccagaagcgt tatttttcta ctgattttct gatcattttt gttccacgtg tatcatcgca
10801 tgacaatcgt tcttgcaaat tttcctgtaa aatttttgaa gtatgtaaac ctacaggatc
10861 atcaatatct gttttatgag aatgattcaa aatacaagaa ttcatcctgt tggattttga
10921 aatccaatca tattaatttc atcggtttca ttctaacaag tgttttgagt ttcagtggtt
10981 ttgcatccat ttggtttcaa gaattctgtt ttcaggacac aagtgtttat gttgatactc
11041 agatatttag atactaatat aatctaagga attgtgtacc aattacataa ttcatctcta
11101 atttccggat tacatataat tatcaattta tcataatatg tgatgaaaat atatttatat
11161 tacaaatcta ctacagtaag ctctttaata ttttagatca ctttgatatt tactctattt
11221 ctgcagaatg ttgctaagat attgaatatt agttctaaag ctctcaaacc tttacttgac
11281 tttgaagact atgatctgta acttaatcgc catttttctc tcacttgcag tcccctagtt
11341 acagctacct ttcccctaga acaagagggt cctctgtggt gaattcatac cgttctgtaa
11401 caccgtccaa tgagggggat gatgacggat attgaccaat caaatgacat tatgtggatt
11461 gtgtttagga gatgcgagtt ttgctttgat tccacatcat caagactatt agtgaaatcg
11521 tactgaccaa aagataaaaa tgctgctgtt atttgtgtgt attcagcgga ctaagtgtgg
11581 atgagcattt ctatattctt cgacgtgaaa aacatttgtc acatatacaa ctactgttac
11641 atgagcaggt cccattcagc gactccgtcc aacaaaaagt tgccttataa cacagccttg
11701 cgggtgaaaa attccctgga tggatttttc atttgcttgt gacttgtgcc ccgatgtttt
11761 tatgtttatt tatgaaatat gcaataatat ttcttctcag agagattgtg attgtagtgt
11821 tacttgttga taatattatt atcataaagc aataatttat tagctttaaa ttattaatat
11881 taaataatta ttataaaaat catcttgaga tggtcccttt tagagggaag cttacggata
11941 caatactcag atgatccctc attggacaaa aatgcatacc ggaaacaaca aatatgtttg
12001 atttgtttcc gtgttgcggt ttaagataat gacgattata tgatgatgaa ccttaataaa
12061 gctcttctat gatatat
//