LOCUS VTW47540.1 1098 aa PRT CON 06-FEB-2024
DEFINITION Caenorhabditis elegans IRS-type PTB domain-containing
protein protein.
ACCESSION BX284606-1644
PROTEIN_ID VTW47540.1
SOURCE Caenorhabditis elegans
ORGANISM Caenorhabditis elegans
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
Caenorhabditis.
REFERENCE 1 (bases 1 to 17718942)
AUTHORS WormBase.
CONSRTM WormBase Consortium
JOURNAL Submitted (04-FEB-2024) to the INSDC. WormBase Group, European
Bioinformatics Institute, Cambridge, CB10 1SA, UK. Email:
help@wormbase.org
REFERENCE 2 (bases 1 to 17718942)
AUTHORS Sulson J.E., Waterston R.
JOURNAL Submitted (03-MAR-2003) to the INSDC. Nematode Sequencing Project:
Sanger Institute, Hinxton, Cambridge CB10 1SA, UK and The Genome
Institute at Washington University, St. Louis, MO 63110, USA.
REFERENCE 3 (bases 1 to 17718942)
AUTHORS Sulson J.E., Waterston R.
CONSRTM Caenorhabditis elegans Sequencing Consortium
TITLE Genome sequence of the nematode C. elegans: a platform for
investigating biology
JOURNAL Science 282(5396), 2012-2018(1998).
COMMENT Annotated features correspond to WormBase release WS292.
Protein-coding gene structures below are the result of integration
and manual review of the following types of data: ab initio
predictions by Genefinder (P. Green and L. Hillier, pers. comm.);
alignments to published proteins and cDNAs; genome sequence
conservation with other nematodes (e.g. to C. briggsae using WABA:
Genome Res. 2000. 10:1115-1125); sequence features (such as
trans-splice and polyA sites).
Sources of data: large-scale EST projects of Yuji Kohara
(http://www.ddbj.nig.ac.jp/c-elegans/html/CE_INDEX.html); ORFeome
cloning project (http://worfdb.dfci.harvard.edu); RST large-scale
sequencing project (Genome Res. 2009. 19:2334-2342); IST library
(Science. 2004. 303:540-3); RT-PCR EST set (Ewing B. Green P. 2010
Unpublished); UTRome EST data submission (UTRome v1 Mangone M.
Piano F. 2009); TEC-RED data (PNAS 2004. 101:1650-1655); RNA Deep
sequencing data (454 read clusters - Makedonka Mitreva,
unpublished; Illumina sequence data, Genome Res. 2009. 19:657-66);
Numerous data sets from the modENCODE project (Science. 2010.
330:1775-87); Individual C. elegans Nucleotide Database
submissions; Personal communications with C. elegans researchers;
Non-Coding gene structures below are derived using the following
methods and data: ab initio prediction of tRNAs by tRNAscan-SE
(Nucl. Acids. Res., 25, 955-964); integration and appraisal of
miRNAs from miRBase (http://www.mirbase.org); integration and
appraisal of RFAM predictions (rfam.sanger.ac.uk); 21U-RNAs (Cell.
2006. 127:1193-1207); modENCODE data (Science. 2010. 330:1775-87);
manual curation of novel published ncRNAs from the literature.
FEATURES Qualifiers
source /organism="Caenorhabditis elegans"
/chromosome="X"
/strain="Bristol N2"
/mol_type="genomic DNA"
/db_xref="taxon:6239"
protein /transl_table=1
/gene="ist-1"
/locus_tag="CELE_C54D1.3"
/standard_name="C54D1.3d"
/note="Confirmed by transcript evidence"
/db_xref="UniProtKB/TrEMBL:A0A4V0INB3"
/db_xref="WormBase:WBGene00002163"
intron_pos 44:1 (1/17)
intron_pos 122:0 (2/17)
intron_pos 168:0 (3/17)
intron_pos 226:1 (4/17)
intron_pos 267:2 (5/17)
intron_pos 307:0 (6/17)
intron_pos 369:2 (7/17)
intron_pos 373:2 (8/17)
intron_pos 450:2 (9/17)
intron_pos 468:2 (10/17)
intron_pos 542:2 (11/17)
intron_pos 589:0 (12/17)
intron_pos 656:0 (13/17)
intron_pos 737:2 (14/17)
intron_pos 791:2 (15/17)
intron_pos 952:1 (16/17)
intron_pos 1000:2 (17/17)
BEGIN
1 MLPAEPTSGE PKNDGEYVET MFDATEEKKQ ETIAPKQEET VKKLSMAARE ERIRESRQQG
61 QLKEKRLKNP DSKGDTSHDK PTRETWKPLA VEDLPKDEDP DEFGIPEVYK CGNCLVGFAP
121 VKKKKLMFVT LTERCLELHE SEKSYRAGKA AKHMVDLSMS FNVHSEHYDA KLKKCLCLMG
181 PDETICMRPE GGILTIEGWR RAIVKLIHES RRRKMDRVPR PEDIFDAAYD VRVCLFPKNL
241 EKYVESLKTD GFTNICTVAK ELLGKKRLCL YPNTLAIVDL CIEPTAYGLP PAGFPPFRAS
301 SMFILERNTV AYYGFRENYF YVRIGKGSPY RGFELLFQVD TNEVCKEIYS RLRALADRDL
361 ENRKQESIRR PESDMHGMES LSVPSPLLHR TKLSLDSPVI TPRDRRLMLG RECLSFASLE
421 KDDSAPSSPF ANYNRPRGSL GNFQLDHLSR FDQPRGSIHS LGNIPIDRPR VSTLQSVKPG
481 KEETGLREAL LESYGHLRKK NSTQSERGEI VVPEQERKMS DNRPRLRTQD IKTVTKPELK
541 SEEPIRPRLP PLKFNANKPS GEFLLSLQRE KELMEEARKN GYDGRTHNPD GTPREIKKDF
601 LDTVCPQAAA PEVVIKEKII NNDTYTLMGP ADWGKLEDIV KDDYSDSGDS CYSSRRGTGS
661 QPTRPAASHL ACQMQNRTQS FGAKQQTFQN RLPPTVNLPD SERKISAANQ GTSNQLDLPQ
721 EDPRKRAFSL GSKNFFNLIG LNDFRRLVSK RHRTSSPNHT STSGISLNSS NASPSASSNF
781 LASSEYLEHA RTDSFGSARS SPKSLHTQRT SSPKRRSDED LISIDFSRLG KNSASDTKRF
841 PFGGGGPGGS FDYDREKREK EDNNRRDREK AAMDLKRKEE WEARELAEKK RELERKIQAK
901 KDRKLEKGRG KDREKDKDHD HDKEFRPKAD SGIADCTPSS SFSGKKDHKN DGSSDSAYMD
961 KEGLKYLADI KKRKKEQGAI DTTNSSSSSL STIVSIEDNK VTRRITETVE TKVVTADLAK
1021 ALGAIDPNRR SSACIEINRK PSICTAIMEE REGEASETDS RGEPSDRKTT AAPVTRKPAS
1081 TGSSMSPFRR LKFLSFRK
//