LOCUS       SIU02522.1               390 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Antiactivator
            of flagellar biosynthesis FleN, an ATPase protein.
ACCESSION   LT708304-3936
PROTEIN_ID  SIU02522.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB3890"
                     /note="Mb3890, -, len: 390 aa. Equivalent to Rv3860, len:
                     390 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.7% identity in 390 aa overlap). Conserved hypothetical
                     protein, showing similarity with hypothetical proteins
                     from Mycobacterium leprae e.g. Q9CDD8|ML0048 (586 aa),
                     FASTA scores: opt: 484, E(): 5.5e-14, (29.95% identity in
                     407 aa overlap); O33082|MLCB628.11c (478 aa) FASTA scores:
                     opt: 484, E(): 4.8e-14, (29.95% identity in 407 aa
                     overlap); etc. Also some similarity with O86637|SC3C3.03c
                     HYPOTHETICAL 112.1 KDA PROTEIN from Streptomyces
                     coelicolor(1083 aa), FASTA scores: opt: 483, E(): 9.6e-14,
                     (30.45% identity in 404 aa overlap). And some similarity
                     with other proteins from Mycobacterium tuberculosis
                     (strains H37Rv and CDC1551) e.g.
                     O05456|Rv3888c|MTCY15F10.24 HYPOTHETICAL 37.7 KDA PROTEIN
                     (341 aa), FASTA scores: opt: 603, E(): 2.8e-19, (35.2%
                     identity in 284 aa overlap); O06396|Rv0530|MTCY25D10.09
                     HYPOTHETICAL 43.0 KDA PROTEIN (405 aa), FASTA scores: opt:
                     538, E(): 2e-16, (31.0% identity in 371 aa overlap);
                     O69740|Rv3876|MTV027.11 (666 aa), FASTA scores: opt: 475,
                     E(): 1.5e-13, (30.2% identity in 391 aa overlap); etc.
                     Contains PS00017 ATP/GTP-binding site motif A (P-loop).
                     Protein product from Mb3890 detected using SWATH mass
                     spectrometry. Mb3890 found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="InterPro:IPR002586"
                     /db_xref="InterPro:IPR027417"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y5G0"
BEGIN
        1 MYERDEFLRD RIRPHQPGTP RGYSPRPPSG DRCPAPPPGR HAAAATPPGP PRLPSAPLRP
       61 LPDPAWPRQP EAPPPSTWAD PALAPIRSRT RPGERGWRRM VRLVTFGLVG LGRSGMQRQE
      121 AQFEATIRTV LHGNHKVAVL GKGGVGKTSV AACVGSILAE LRQQDRIVGI DADTAFGRLS
      181 SRIDPRAAGS FWELTTDTNL RSFTDITARL GRNSAGLYVL AGQPASGPRR ALDPAIYREA
      241 ALRLDHHFAI SVIDCGSSME AAVTQEVLRD VDALIVVSSP WADGASAAAN TIEWLSDYGL
      301 TGLLRRSIVV LNDSDGHADK RTKSLLAQEF IDHGQPVVEV PFDPHLRPGG VIDMSHEMAP
      361 TTRLKILQVA ATVTAYFASR PADAHGSPPR
//