LOCUS SIU02522.1 390 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 Antiactivator of flagellar biosynthesis FleN, an ATPase protein. ACCESSION LT708304-3936 PROTEIN_ID SIU02522.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB3890" /note="Mb3890, -, len: 390 aa. Equivalent to Rv3860, len: 390 aa, from Mycobacterium tuberculosis strain H37Rv, (99.7% identity in 390 aa overlap). Conserved hypothetical protein, showing similarity with hypothetical proteins from Mycobacterium leprae e.g. Q9CDD8|ML0048 (586 aa), FASTA scores: opt: 484, E(): 5.5e-14, (29.95% identity in 407 aa overlap); O33082|MLCB628.11c (478 aa) FASTA scores: opt: 484, E(): 4.8e-14, (29.95% identity in 407 aa overlap); etc. Also some similarity with O86637|SC3C3.03c HYPOTHETICAL 112.1 KDA PROTEIN from Streptomyces coelicolor(1083 aa), FASTA scores: opt: 483, E(): 9.6e-14, (30.45% identity in 404 aa overlap). And some similarity with other proteins from Mycobacterium tuberculosis (strains H37Rv and CDC1551) e.g. O05456|Rv3888c|MTCY15F10.24 HYPOTHETICAL 37.7 KDA PROTEIN (341 aa), FASTA scores: opt: 603, E(): 2.8e-19, (35.2% identity in 284 aa overlap); O06396|Rv0530|MTCY25D10.09 HYPOTHETICAL 43.0 KDA PROTEIN (405 aa), FASTA scores: opt: 538, E(): 2e-16, (31.0% identity in 371 aa overlap); O69740|Rv3876|MTV027.11 (666 aa), FASTA scores: opt: 475, E(): 1.5e-13, (30.2% identity in 391 aa overlap); etc. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Protein product from Mb3890 detected using SWATH mass spectrometry. Mb3890 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="InterPro:IPR002586" /db_xref="InterPro:IPR027417" /db_xref="UniProtKB/TrEMBL:A0A1R3Y5G0" BEGIN 1 MYERDEFLRD RIRPHQPGTP RGYSPRPPSG DRCPAPPPGR HAAAATPPGP PRLPSAPLRP 61 LPDPAWPRQP EAPPPSTWAD PALAPIRSRT RPGERGWRRM VRLVTFGLVG LGRSGMQRQE 121 AQFEATIRTV LHGNHKVAVL GKGGVGKTSV AACVGSILAE LRQQDRIVGI DADTAFGRLS 181 SRIDPRAAGS FWELTTDTNL RSFTDITARL GRNSAGLYVL AGQPASGPRR ALDPAIYREA 241 ALRLDHHFAI SVIDCGSSME AAVTQEVLRD VDALIVVSSP WADGASAAAN TIEWLSDYGL 301 TGLLRRSIVV LNDSDGHADK RTKSLLAQEF IDHGQPVVEV PFDPHLRPGG VIDMSHEMAP 361 TTRLKILQVA ATVTAYFASR PADAHGSPPR //