LOCUS       SIU02510.1               302 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            CONSERVED TRANSMEMBRANE PROTEIN protein.
ACCESSION   LT708304-3924
PROTEIN_ID  SIU02510.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB3878"
                     /note="Mb3878, -, len: 302 aa. Equivalent to Rv3848, len:
                     302 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.7% identity in 302 aa overlap). Probable conserved
                     transmembrane protein, similar to hypothetical
                     (transmembrane) proteins e.g. Q9HVG2|PA4629 HYPOTHETICAL
                     PROTEIN from Pseudomonas aeruginosa (192 aa), FASTA
                     scores: opt: 304, E(): 5.3e-11, (35.05% identity in 174 aa
                     overlap); Q9A5S7|CC2370 HYPOTHETICAL PROTEIN from
                     Caulobacter crescentus (207 aa), FASTA scores: opt: 285,
                     E(): 7.4e-10, (29.9% identity in 184 aa overlap);
                     Q9KY43|SCC8A.05c PUTATIVE INTEGRAL MEMBRANE PROTEIN from
                     Streptomyces coelicolor (193 aa), FASTA scores: opt: 245,
                     E(): 1.6e-07, (32.8% identity in 195 aa overlap); etc.
                     Protein product from Mb3878 detected using shotgun mass
                     spectrometry and SWATH mass spectrometry. Mb3878 found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing (TPM > 20)."
                     /db_xref="GOA:A0A1R3Y5F1"
                     /db_xref="InterPro:IPR001727"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y5F1"
BEGIN
        1 MLAATLLSLG AVFLAELGDR SQLITMTYTL RYRWWVVLTG VAIAAFTVHG VAVAIGHFLG
       61 STVPARPAAC VSAIAFLIFA VWVWREDTAS DSETSPTAAE PRLALFTVVS SFALAELGDK
      121 TTLATVTLAS DHHWAGVWIG TTLGMILADG LAIGAGLLLH RRLPERLLQV LTGLLFLLFG
      181 LWLLFDDALG FRSIAIAVTA AVVLAAATTA VSVRVAQTRR RRPTAAATPE DDSTRPERSS
      241 VAPGHPGSIL LPLPEVSLRG RRPPSGSPDE RCADPGSKGG SRRISVGCWL PGVGRIRPTR
      301 SS
//