LOCUS       SIU02500.1               181 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 bacterioferritin 
            bfrb protein.
ACCESSION   LT708304-3914
PROTEIN_ID  SIU02500.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="bfrB"
                     /locus_tag="BQ2027_MB3871"
                     /note="Mb3871, bfrB, len: 181 aa. Equivalent to Rv3841,
                     len: 181 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 181 aa overlap). Possible bfrB,
                     bacterioferritin, similar to other ferritin or
                     hypothetical proteins e.g. O26261|MTH158|RSGA FERRITIN
                     LIKE PROTEIN from Methanothermobacter thermautotrophicus
                     (171 aa), FASTA scores: opt: 277, E(): 6.6e-11, (30.1%
                     identity in 166 aa overlap); Q99SZ3|SA1709 HYPOTHETICAL
                     PROTEIN from Staphylococcus aureus subsp. aureus N315 (166
                     aa), FASTA scores: opt: 275, E(): 8.7e-11, (33.35%
                     identity in 156 aa overlap); Q9X0L2|TM1128 FERRITIN from
                     Thermotoga maritima (164 aa), FASTA scores: opt: 247, E():
                     5.3e-09, (25.65% identity in 156 aa overlap);
                     Q9KDT7|BH1124 FERRITIN from Bacillus halodurans (169 aa),
                     FASTA scores: opt: 246, E(): 6.3e-09, (28.95% identity in
                     152 aa overlap); O29424|AF0834 PUTATIVE FERRITIN from
                     Archaeoglobus fulgidu (169 aa), FASTA scores: opt: 246,
                     E(): 6.3e-09, (28.95% identity in 152 aa overlap); etc.
                     Also shows similarity with Rv1876|MTCY180.42|BFRA PROBABLE
                     BACTERIOFERRITIN from Mycobacterium tuberculosis (159 aa).
                     SEEMS BELONG TO THE BACTERIOFERRITIN FAMILY. Protein
                     product from Mb3871 detected using shotgun mass
                     spectrometry and SWATH mass spectrometry. Mb3871 found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /db_xref="GOA:A0A1R3Y5E2"
                     /db_xref="InterPro:IPR001519"
                     /db_xref="InterPro:IPR008331"
                     /db_xref="InterPro:IPR009040"
                     /db_xref="InterPro:IPR009078"
                     /db_xref="InterPro:IPR012347"
                     /db_xref="InterPro:IPR041719"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y5E2"
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MTEYEGPKTK FHALMQEQIH NEFTAAQQYV AIAVYFDSED LPQLAKHFYS QAVEERNHAM
       61 MLVQHLLDRD LRVEIPGVDT VRNQFDRPRE ALALALDQER TVTDQVGRLT AVARDEGDFL
      121 GEQFMQWFLQ EQIEEVALMA TLVRVADRAG ANLFELENFV AREVDVAPAA SGAPHAAGGR
      181 L
//