LOCUS       SIU02487.1               203 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE
            RESOLVASE protein.
ACCESSION   LT708304-3901
PROTEIN_ID  SIU02487.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB3858C"
                     /note="Mb3858c, -, len: 203 aa. Equivalent to Rv3828c, len
                     203 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 203 aa overlap). Possible resolvase
                     within IS1537 element, similar to others e.g.
                     Q97X40|SSO1915 FIRST ORF IN TRANSPOSON ISC1913 from
                     Sulfolobus solfataricus (213 aa), FASTA scores: opt: 275,
                     E(): 1.6e-11, (30.6% identity in 196 aa overlap);
                     Q9V1M0|PAB2076 RESOLVASE RELATED PROTEIN from Pyrococcus
                     abyssi (212 aa), FASTA scores: opt: 254, E(): 4.2e-10,
                     (29.95% identity in 197 aa overlap); Q9RMU7|ORFA PUTATIVE
                     TRANSPOSASE (BELONGS TO THE MERR FAMILY OF TRANSCRIPTIONAL
                     REGULATORS) from elicobacter pylori (Campylobacter pylori)
                     (217 aa), FASTA scores: opt: 243, E(): 2.3e-09, (31.8%
                     identity in 154 aa overlap); etc. Also highly similar to
                     proteins from Mycobacterium tuberculosis e.g.
                     O33334|Rv2792c|MTV002.57c RESOLVASE (193 aa), FASTA
                     scores: opt: 970, E(): 1.5e-58, (79.25% identity in 193 aa
                     overlap); O07773|Rv0605|MTCY19H5.17c PUTATIVE RESOLVASE
                     (202 aa), FASTA scores: opt: 964, E(): 4e-58, (76.25%
                     identity in 202 aa overlap); P95116|Rv2979c|MTCY349.08
                     HYPOTHETICAL 21.4 KDA PROTEIN (194 aa), FASTA scores: opt:
                     895, E(): 1.8e-53, (74.75% identity in 194 aa overlap);
                     Q10831|YS86_MYCTU|Rv2886c|MT2954|MTCY274.17c HYPOTHETICAL
                     31.9 KDA PROTEIN (295 aa), FASTA scores: opt: 826, E():
                     1.1e-48, (66.2% identity in 204 aa overlap) (similarity
                     only at C-terminus); etc. Contains PS00397 Site-specific
                     recombinases active site. Possible helix-turn-helix motif
                     from aa 11-32, Score 1305 (+3.63 SD)."
                     /db_xref="GOA:A0A1R3Y5C9"
                     /db_xref="InterPro:IPR006118"
                     /db_xref="InterPro:IPR006119"
                     /db_xref="InterPro:IPR036162"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y5C9"
BEGIN
        1 MSVVCCRNRW MNLAVWAERN GVAWVIAYRW FRAGLLPVPA QRVGRLILVN DPAVEESGRG
       61 RTLVYARVSS ADQRSDLDRR VARVTAWATS QHLSVDKVVA EGGWALNGHR RKFFALLGDP
      121 VVTRIVVEHR DRFCWFGSEY VEAALVAQGR ELVVVDLAEV DDDLVGDMTE ILTSMCARLY
      181 GERAAQNGAK RALAAAVGDA EAA
//