LOCUS       SIU02472.1               273 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Cof
            family hydrolase protein.
ACCESSION   LT708304-3886
PROTEIN_ID  SIU02472.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB3843C"
                     /note="Mb3843c, -, len: 273 aa. Equivalent to Rv3813c,
                     len: 273 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.6% identity in 273 aa overlap). Conserved hypothetical
                     protein, equivalent to Q9CDB9|ML0089 HYPOTHETICAL PROTEIN
                     from Mycobacterium leprae (281 aa) FASTA scores: opt:
                     1479, E(): 9.6e-81, (80.45% identity in 271 aa overlap);
                     and similar to Q98LI0|MLL1014 from (280 aa) . Also similar
                     to many hypothetical proteins from several organisms e.g.
                     Q9ZBX2|SCD78.27c from Streptomyces coelicolor (280 aa),
                     FASTA scores: opt: 597, E(): 2.2e-28, (43.25% identity in
                     266 aa overlap); Q9RXR7|DR0240 from Deinococcus
                     radiodurans (284 aa), FASTA scores: opt: 543, E():
                     3.5e-25, (38.65% identity in 264 aa overlap);
                     Q99YH5|SPY1700 from Streptococcus pyogenes (274 aa) FASTA
                     scores: opt: 373, E(): 4.3e-15, (30.75% identity in 270 aa
                     overlap); P70947|YITU from Bacillus subtilis (270 aa)
                     FASTA scores: opt: 353, E(): 6.5e-14, (30.0% identity in
                     280 aa overlap); etc. Protein product from Mb3843c
                     detected using shotgun mass spectrometry and SWATH mass
                     spectrometry. Mb3843c found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:A0A1R3Y5B8"
                     /db_xref="InterPro:IPR000150"
                     /db_xref="InterPro:IPR006379"
                     /db_xref="InterPro:IPR023214"
                     /db_xref="InterPro:IPR036412"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y5B8"
BEGIN
        1 MKPTVPALVA CDVDGTLLDD GETVTKRTRD AVHAAVDAGT HFILATGRPP RWVRPIVDAL
       61 GFAPMAVCAN GAVIYDPGTD RVTSVRTLPV DALATLAEVA TRVIPGAGLA VERIGERAHD
      121 TATPQFVSSP GYEHAWLNPD NTEVSIDHLL SAPAIKLLIR KAGAASADMA AELAKHVGFE
      181 GDITYSTNNG LVEIVPLGIS KATGVDEIAR PLGISDAEVV AFGDMPNDVP MLLRAGLGVA
      241 MGNAHPDALA VADEVTAPNS EDGVARVLER WWS
//