LOCUS SIU02450.1 643 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 arabinofuranosylt ransferase afta protein. ACCESSION LT708304-3864 PROTEIN_ID SIU02450.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="afta" /locus_tag="BQ2027_MB3821" /note="Mb3821, -, len: 643 aa. Equivalent to Rv3792, len: 643 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 643 aa overlap). Probable conserved transmembrane protein, equivalent, but longer 21 aa, to Q9CDA6|ML0107 PUTATIVE MEMBRANE PROTEIN from Mycobacterium leprae (632 aa), FASTA scores: opt: 1981, E(): 2.1e-110, (77.5% identity in 631 aa overlap). C-terminal end highly similar to C-terminus of O05765 PUTATIVE PRODUCT ORF 3 from Mycobacterium smegmatis (603 aa), FASTA scores: opt: 1261, E(): 1.4e-67, (70.7% identity in 266 aa overlap). Protein product from Mb3821 detected using SWATH mass spectrometry. Mb3821 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:Q7TVN5" /db_xref="InterPro:IPR020959" /db_xref="InterPro:IPR020963" /db_xref="UniProtKB/Swiss-Prot:Q7TVN5" BEGIN 1 MPSRRKSPQF GHEMGAFTSA RAREVLVALG QLAAAVVVAV GVAVVSLLAI ARVEWPAFPS 61 SNQLHALTTV GQVGCLAGLV GIGWLWRHGR FRRLARLGGL VLVSAFTVVT LGMPLGATKL 121 YLFGISVDQQ FRTEYLTRLT DTAALRDMTY IGLPPFYPPG WFWIGGRAAA LTGTPAWEMF 181 KPWAITSMAI AVAVALVLWW RMIRFEYALL VTVATAAVML AYSSPEPYAA MITVLLPPML 241 VLTWSGLGAR DRQGWAAVVG AGVFLGFAAT WYTLLVAYGA FTVVLMALLL AGSRLQSGIK 301 AAVDPLCRLA VVGAIAAAIG STTWLPYLLR AARDPVSDTG SAQHYLPADG AALTFPMLQF 361 SLLGAICLLG TLWLVMRARS SAPAGALAIG VLAVYLWSLL SMLATLARTT LLSFRLQPTL 421 SVLLVAAGAF GFVEAVQALG KRGRGVIPMA AAIGLAGAIA FSQDIPDVLR PDLTIAYTDT 481 DGYGQRGDRR PPGSEKYYPA IDAAIRRVTG KRRDRTVVLT ADYSFLSYYP YWGFQGLTPH 541 YANPLAQFDK RATQIDSWSG LSTADEFIAA LDKLPWQPPT VFLMRHGAHN SYTLRLAQDV 601 YPNQPNVRRY TVDLRTALFA DPRFVVEDIG PFVLAIRKPQ ESA //