LOCUS       SIU02438.1               178 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Bacterial
            proteasome activator protein.
ACCESSION   LT708304-3852
PROTEIN_ID  SIU02438.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="bpa"
                     /locus_tag="BQ2027_MB3809"
                     /note="Mb3809, -, len: 178 aa. Equivalent to Rv3780, len:
                     178 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 178 aa overlap). Conserved
                     hypothetical protein, equivalent to Q9CD99|ML0115
                     HYPOTHETICAL 19.1 KDA PROTEIN from Mycobacterium leprae
                     (174 aa), FASTA scores: opt: 903, E(): 2.3e-48, (82.95%
                     identity in 170 aa overlap). Also highly similar to
                     Q9XA56|SCGD3.23c HYPOTHETICAL 19.5 KDA PROTEIN from
                     Streptomyces coelicolor (179 aa), FASTA scores: opt: 692,
                     E(): 1.8e-35, (65.9% identity in 170 aa overlap). Note
                     that this putative protein is 4 aa longer at the
                     N-terminus compared to previous annotation (in Nature 393:
                     537-544 (1998)). Protein product from Mb3809 detected
                     using shotgun mass spectrometry and SWATH mass
                     spectrometry. Mb3809 found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:P65092"
                     /db_xref="InterPro:IPR019695"
                     /db_xref="UniProtKB/Swiss-Prot:P65092"
BEGIN
        1 MRKRMVIGLS TGSDDDDVEV IGGVDPRLIA VQENDSDESS LTDLVEQPAK VMRIGTMIKQ
       61 LLEEVRAAPL DEASRNRLRD IHATSIRELE DGLAPELREE LDRLTLPFNE DAVPSDAELR
      121 IAQAQLVGWL EGLFHGIQTA LFAQQMAARA QLQQMRQGAL PPGVGKSGQH GHGTGQYL
//