LOCUS SIU02438.1 178 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 Bacterial proteasome activator protein. ACCESSION LT708304-3852 PROTEIN_ID SIU02438.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="bpa" /locus_tag="BQ2027_MB3809" /note="Mb3809, -, len: 178 aa. Equivalent to Rv3780, len: 178 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 178 aa overlap). Conserved hypothetical protein, equivalent to Q9CD99|ML0115 HYPOTHETICAL 19.1 KDA PROTEIN from Mycobacterium leprae (174 aa), FASTA scores: opt: 903, E(): 2.3e-48, (82.95% identity in 170 aa overlap). Also highly similar to Q9XA56|SCGD3.23c HYPOTHETICAL 19.5 KDA PROTEIN from Streptomyces coelicolor (179 aa), FASTA scores: opt: 692, E(): 1.8e-35, (65.9% identity in 170 aa overlap). Note that this putative protein is 4 aa longer at the N-terminus compared to previous annotation (in Nature 393: 537-544 (1998)). Protein product from Mb3809 detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb3809 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:P65092" /db_xref="InterPro:IPR019695" /db_xref="UniProtKB/Swiss-Prot:P65092" BEGIN 1 MRKRMVIGLS TGSDDDDVEV IGGVDPRLIA VQENDSDESS LTDLVEQPAK VMRIGTMIKQ 61 LLEEVRAAPL DEASRNRLRD IHATSIRELE DGLAPELREE LDRLTLPFNE DAVPSDAELR 121 IAQAQLVGWL EGLFHGIQTA LFAQQMAARA QLQQMRQGAL PPGVGKSGQH GHGTGQYL //