LOCUS       SIU02430.1               114 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 CONSERVED
            HYPOTHETICAL PROTEIN [SECOND PART] protein.
ACCESSION   LT708304-3844
PROTEIN_ID  SIU02430.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB3801C"
                     /note="Mb3801c, -, len: 114 aa. Equivalent to 3' end of
                     Rv3773c, len: 194 aa, from Mycobacterium tuberculosis
                     strain H37Rv, (100.0% identity in 114 aa overlap).
                     Hypothetical protein, highly similar to C-terminal end of
                     O53773|Rv0576|MTV039.14 POSSIBLE TRANSCRIPTIONAL REGULATOR
                     from Mycobacterium tuberculosis (434 aa), FASTA scores:
                     opt: 575, E(): 8.3e-30, (47.4% identity in 192 aa
                     overlap); and some similarity with other proteins from
                     Mycobacterium tuberculosis e.g. P71985|Rv1727|MTCY04C12.12
                     (189 aa) FASTA scores: opt: 176, E(): 0.00022, (31.1%
                     identity in 180 aa overlap).
                     REMARK-M.bovis-M.tuberculosis: In Mycobacterium
                     tuberculosis Rv3773c exists as a single gene. In
                     Mycobacterium bovis, a frameshift due to a single base
                     insertion (*-a) splits Rv3773c in two parts, Mb3802c and
                     Mb3801c. Protein product from Mb3801c detected using SWATH
                     mass spectrometry. Mb3801c found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="InterPro:IPR017517"
                     /db_xref="InterPro:IPR017520"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y567"
BEGIN
        1 MERLVSGAAR SALDAWHRHG LEGDVSLGPG SMSAKVAVSV FSVEFLVHAW DYAVAVGSEL
       61 KAADSLAEYV LELARKLIKP EERSVAGFNE PVDVPEDGGA LERLIAFTGR NPAR
//