LOCUS SIU02430.1 114 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 CONSERVED HYPOTHETICAL PROTEIN [SECOND PART] protein. ACCESSION LT708304-3844 PROTEIN_ID SIU02430.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB3801C" /note="Mb3801c, -, len: 114 aa. Equivalent to 3' end of Rv3773c, len: 194 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 114 aa overlap). Hypothetical protein, highly similar to C-terminal end of O53773|Rv0576|MTV039.14 POSSIBLE TRANSCRIPTIONAL REGULATOR from Mycobacterium tuberculosis (434 aa), FASTA scores: opt: 575, E(): 8.3e-30, (47.4% identity in 192 aa overlap); and some similarity with other proteins from Mycobacterium tuberculosis e.g. P71985|Rv1727|MTCY04C12.12 (189 aa) FASTA scores: opt: 176, E(): 0.00022, (31.1% identity in 180 aa overlap). REMARK-M.bovis-M.tuberculosis: In Mycobacterium tuberculosis Rv3773c exists as a single gene. In Mycobacterium bovis, a frameshift due to a single base insertion (*-a) splits Rv3773c in two parts, Mb3802c and Mb3801c. Protein product from Mb3801c detected using SWATH mass spectrometry. Mb3801c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="InterPro:IPR017517" /db_xref="InterPro:IPR017520" /db_xref="UniProtKB/TrEMBL:A0A1R3Y567" BEGIN 1 MERLVSGAAR SALDAWHRHG LEGDVSLGPG SMSAKVAVSV FSVEFLVHAW DYAVAVGSEL 61 KAADSLAEYV LELARKLIKP EERSVAGFNE PVDVPEDGGA LERLIAFTGR NPAR //