LOCUS       SIU02415.1               100 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE
            CONSERVED MEMBRANE PROTEIN protein.
ACCESSION   LT708304-3829
PROTEIN_ID  SIU02415.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB3786"
                     /note="Mb3786, -, len: 100 aa. Equivalent to Rv3760, len:
                     100 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 100 aa overlap). Possible conserved
                     membrane protein, equivalent to Q50094|ML2366|MLCB12.11c
                     PUTATIVE MEMBRANE PROTEIN from Mycobacterium leprae (113
                     aa), FASTA scores: opt: 423, E(): 1.2e-20, (67.7% identity
                     in 99 aa overlap). Also similar with Q9JST1|NMA2149
                     PUTATIVE INNER MEMBRANE HYPOTHETICAL PROTEIN from
                     Neisseria meningitidis (serogroup A) (104 aa), FASTA
                     scores: opt: 113, E(): 0.95, (33.85% identity in 62 aa
                     overlap); and showing similarity with Q9ZAX7 ABC
                     TRANSPORTER MEMBRANE PROTEIN SUBUNIT from Streptococcus
                     mutans (498 aa), FASTA scores: opt: 108, E(): 6.7, (42.35%
                     identity in 85 aa overlap) (similarity at C-terminus); and
                     P33108|SECY_MICLU PREPROTEIN TRANSLOCASE SECY SUBUNIT from
                     Micrococcus luteus (Micrococcus lysodeikticus) (436 aa),
                     FASTA scores: opt: 106, E(): 8.2, (29.05% identity in 86
                     aa overlap). Equivalent to AAK48231 from Mycobacterium
                     tuberculosis strain CDC1551 (117 aa) but shorter 17 aa.
                     Protein product from Mb3786 detected using shotgun mass
                     spectrometry and SWATH mass spectrometry. Mb3786 found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing (TPM > 20)."
                     /db_xref="GOA:A0A1R3Y6N8"
                     /db_xref="InterPro:IPR010445"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y6N8"
BEGIN
        1 MPGSVPGKAP EEPPVKFTRA AAVWSALIVG FLILILLLIF IAQNTASAQF AFFGWRWSLP
       61 LGVAILLAAV GGGLITVFAG TARILQLRRA AKKTHAAALR
//