LOCUS SIU02410.1 199 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 conserved protein protein. ACCESSION LT708304-3824 PROTEIN_ID SIU02410.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB3781C" /note="Mb3781c, -, len: 199 aa. Equivalent to Rv3755c, len: 199 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 199 aa overlap). Conserved hypothetical protein showing similarity to CAC47343|SMC03980 CONSERVED HYPOTHETICAL PROTEIN from Rhizobium meliloti (Sinorhizobium meliloti) (196 aa) FASTA scores: opt: 244, E(): 4.1e-09, (30.9% identity in 191 aa overlap); Q9I2B5|PA1994 from Pseudomonas aeruginosa (187 aa), FASTA scores: opt: 226, E(): 6e-08, (29.9% identity in 194 aa overlap); and Q98N73|MLR0268 HYPOTHETICAL PROTEIN (183 aa), FASTA scores: opt: 234, E(): 1.8e-08, (27.05% identity in 185 aa overlap). Protein product from Mb3781c detected using shotgun mass spectrometry. Mb3781c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing (TPM > 20)." /db_xref="InterPro:IPR009467" /db_xref="UniProtKB/TrEMBL:A0A1R3Y540" BEGIN 1 MNAVPSDLTP RVWPAMLTWR AQDISRMESV RVQLSGKRIR ANGRIVAAAT ANNPAFGAHY 61 DLQTDETGAT KRFGLTVTLA ERERQLAIAR DEENMWLVTD HQGERRAAYN GALDIDLVFS 121 PFFNALPIRR LGLHERAESI ALPVVYVNVP EMSVDAATVS YTSEGRLDGI KLRSPVADTT 181 VTVDSDGFIV DYPGLAERM //