LOCUS       SIU02391.1               162 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 CONSERVED
            HYPOTHETICAL PROTEIN protein.
ACCESSION   LT708304-3805
PROTEIN_ID  SIU02391.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB3762"
                     /note="Mb3762, -, len: 162 aa. Equivalent to Rv3735, len:
                     162 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 162 aa overlap). Conserved
                     hypothetical protein, highly similar to several bacterial
                     hypothetical proteins e.g.
                     Q9UX41|ORF-C09_016|SSO0651|AAK40956 from Sulfolobus
                     solfataricus (163 aa), FASTA scores: opt: 627, E():
                     1.2e-34, (55.9% identity in 161 aa overlap); O26795|MTH699
                     from Methanobacterium thermoautotrophicum (168 aa), FASTA
                     scores: opt: 616, E(): 6.7e-34, (56.1% identity in 155 aa
                     overlap); |Q9Y9J9|APE2289 from Aeropyrum pernix (191 aa),
                     FASTA scores: opt: 591, E(): 3.4e-32, (54.65% identity in
                     161 aa overlap); etc. Contains PS00435 Peroxidases
                     proximal heme-ligand signature. Protein product from
                     Mb3762 detected using SWATH mass spectrometry. Mb3762
                     found to be expressed during exponential growth in
                     Sauton's minimal media by RNA-sequencing (TPM > 20)."
                     /db_xref="InterPro:IPR007153"
                     /db_xref="InterPro:IPR036902"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y531"
BEGIN
        1 MSLAWDVVSV DKPDDVNVVI GQAHFIKAVE DLHEAMVGVS PSLRFGLAFC EASGPRLVRH
       61 TGNDGDLVEL ATRTALAIAA GHSFVIFLRE GFPINILNPV QAVPEVCTIY CATANPVDVV
      121 VAVTPHGRGI VGVVDGQTPL GVETDRDIAQ RRDLLRAIGY KL
//