LOCUS SIU02391.1 162 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 CONSERVED HYPOTHETICAL PROTEIN protein. ACCESSION LT708304-3805 PROTEIN_ID SIU02391.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB3762" /note="Mb3762, -, len: 162 aa. Equivalent to Rv3735, len: 162 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 162 aa overlap). Conserved hypothetical protein, highly similar to several bacterial hypothetical proteins e.g. Q9UX41|ORF-C09_016|SSO0651|AAK40956 from Sulfolobus solfataricus (163 aa), FASTA scores: opt: 627, E(): 1.2e-34, (55.9% identity in 161 aa overlap); O26795|MTH699 from Methanobacterium thermoautotrophicum (168 aa), FASTA scores: opt: 616, E(): 6.7e-34, (56.1% identity in 155 aa overlap); |Q9Y9J9|APE2289 from Aeropyrum pernix (191 aa), FASTA scores: opt: 591, E(): 3.4e-32, (54.65% identity in 161 aa overlap); etc. Contains PS00435 Peroxidases proximal heme-ligand signature. Protein product from Mb3762 detected using SWATH mass spectrometry. Mb3762 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing (TPM > 20)." /db_xref="InterPro:IPR007153" /db_xref="InterPro:IPR036902" /db_xref="UniProtKB/TrEMBL:A0A1R3Y531" BEGIN 1 MSLAWDVVSV DKPDDVNVVI GQAHFIKAVE DLHEAMVGVS PSLRFGLAFC EASGPRLVRH 61 TGNDGDLVEL ATRTALAIAA GHSFVIFLRE GFPINILNPV QAVPEVCTIY CATANPVDVV 121 VAVTPHGRGI VGVVDGQTPL GVETDRDIAQ RRDLLRAIGY KL //