LOCUS SIU02390.1 454 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 putative triacylglycerol synthase (diacylglycerol acyltransferase) tgs2 protein. ACCESSION LT708304-3804 PROTEIN_ID SIU02390.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="tgs2" /locus_tag="BQ2027_MB3761C" /note="Mb3761c, -, len: 454 aa. Equivalent to Rv3734c, len: 454 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 454 aa overlap). Hypothetical protein, highly similar to O69707|Y1E0_MYCTU|Rv3740c|MT3848|MTV025. 088c HYPOTHETICAL PROTEIN from Mycobacterium tuberculosis (448 aa), FASTA scores: opt: 1917, E(): 1.3e-111, (61.4% identity in 451 aa overlap); and similar to many other proteins from Mycobacterium tuberculosis (strains H37Rv and CDC1551) e.g. P71694|YE43_MYCTU|Rv1425|MT1468|MTCY21B4 .43|MTCY493.29c (459 aa), FASTA scores: opt: 824, E(): 1.1e-43, (36.5% identity in 460 aa overlap); Q50680|YM85_MYCTU|Rv2285|MT2343|MTCY339.25c (445 aa) FASTA scores: opt: 766, E(): 4.1e-40, (36.4% identity in 453 aa overlap); etc. Also similar to Q9RIU8|SCM11.13c HYPOTHETICAL 47.1 KDA PROTEIN from Streptomyces coelicolor (446 aa), FASTA scores: opt: 331, E(): 4.3e-13, (32.9% identity in 468 aa overlap); and Q9X7A8|ML1244|MLCB1610.05 CONSERVED MEMBRANE PROTEIN from Mycobacterium leprae (491 aa), FASTA scores: opt: 296, E(): 7e-11, (28.35% identity in 413 aa overlap). Contains PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. Start site chosen by homology, but may extend further upstream. Protein product from Mb3761c detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb3761c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:P67211" /db_xref="InterPro:IPR004255" /db_xref="InterPro:IPR009721" /db_xref="InterPro:IPR014292" /db_xref="InterPro:IPR023213" /db_xref="UniProtKB/Swiss-Prot:P67211" BEGIN 1 MDLMMPNDSM FLFIESREHP MHVGGLSLFE PPQGAGPEFV REFTERLVAN DEFQPMFRKH 61 PATIGGGIAR VAWAYDDDID IDYHVRRSAL PSPGRVRDLL ELTSRLHTSL LDRHRPLWEL 121 HVVEGLNDGR FAMYTKMHHA LIDGVSAMKL AQRTLSADPD DAEVRAIWNL PPRPRTRPPS 181 DGSSLLDALF KMAGSVVGLA PSTLKLARAA LLEQQLTLPF AAPHSMFNVK VGGARRCAAQ 241 SWSLDRIKSV KQAAGVTVND AVLAMCAGAL RYYLIERNAL PDRPLIAMVP VSLRSKEDAD 301 AGGNLVGSVL CNLATHVDDP AQRIQTISAS MDGNKKVLSE LPQLQVLALS ALNMAPLTLA 361 GVPGFLSAVP PPFNIVISNV PGPVDPLYYG TARLDGSYPL SNIPDGQALN ITLVNNAGNL 421 DFGLVGCRRS VPHLQRLLAH LESSLKDLEQ AVGI //