LOCUS       SIU02374.1               147 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 conserved
            protein protein.
ACCESSION   LT708304-3788
PROTEIN_ID  SIU02374.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB3745C"
                     /note="Mb3745c, -, len: 147 aa. Equivalent to Rv3718c,
                     len: 147 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 147 aa overlap). Conserved
                     hypothetical protein, equivalent to
                     O69517|ML2332|MLCB2407.18 HYPOTHETICAL 15.5 KDA PROTEIN
                     from Mycobacterium leprae (145 aa), FASTA scores: opt:
                     780, E(): 1.4e-44, (81.95% identity in 144 aa overlap).
                     Also highly similar to Q9ZBJ2|SC9C7.18 CONSERVED
                     HYPOTHETICAL PROTEIN from Streptomyces coelicolor (147 aa)
                     FASTA scores: opt: 475, E(): 1.7e-24, (52.05% identity in
                     146 aa overlap); and showing some similarity to various
                     proteins e.g. P27538|PR2_PETCR PATHOGENESIS-RELATED
                     PROTEIN 2 from Petroselinum crispum (Parsley)
                     (Petroselinum hortense) (158 aa); P92918|ALL2_APIGR MAJOR
                     ALLERGEN API G 2 from Apium graveolens (Celery) (159 aa);
                     etc. Protein product from Mb3745c detected using shotgun
                     mass spectrometry. Mb3745c found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="InterPro:IPR014488"
                     /db_xref="InterPro:IPR019587"
                     /db_xref="InterPro:IPR023393"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y509"
BEGIN
        1 MGQVSAASTI LINAEPTATL DALADYETVR PKILSPHYSE YQVLEGGKGR GTVAKWRLQA
       61 TQSRVRDVQV NVDVAGHTVI EKDMNSSMVT NWTVAPAGPG SSVTVKTTWT GAGGVKGFFE
      121 KTFAPLGLKK IQAEVLSNLK TELEGDA
//