LOCUS SIU02374.1 147 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 conserved protein protein. ACCESSION LT708304-3788 PROTEIN_ID SIU02374.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB3745C" /note="Mb3745c, -, len: 147 aa. Equivalent to Rv3718c, len: 147 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 147 aa overlap). Conserved hypothetical protein, equivalent to O69517|ML2332|MLCB2407.18 HYPOTHETICAL 15.5 KDA PROTEIN from Mycobacterium leprae (145 aa), FASTA scores: opt: 780, E(): 1.4e-44, (81.95% identity in 144 aa overlap). Also highly similar to Q9ZBJ2|SC9C7.18 CONSERVED HYPOTHETICAL PROTEIN from Streptomyces coelicolor (147 aa) FASTA scores: opt: 475, E(): 1.7e-24, (52.05% identity in 146 aa overlap); and showing some similarity to various proteins e.g. P27538|PR2_PETCR PATHOGENESIS-RELATED PROTEIN 2 from Petroselinum crispum (Parsley) (Petroselinum hortense) (158 aa); P92918|ALL2_APIGR MAJOR ALLERGEN API G 2 from Apium graveolens (Celery) (159 aa); etc. Protein product from Mb3745c detected using shotgun mass spectrometry. Mb3745c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="InterPro:IPR014488" /db_xref="InterPro:IPR019587" /db_xref="InterPro:IPR023393" /db_xref="UniProtKB/TrEMBL:A0A1R3Y509" BEGIN 1 MGQVSAASTI LINAEPTATL DALADYETVR PKILSPHYSE YQVLEGGKGR GTVAKWRLQA 61 TQSRVRDVQV NVDVAGHTVI EKDMNSSMVT NWTVAPAGPG SSVTVKTTWT GAGGVKGFFE 121 KTFAPLGLKK IQAEVLSNLK TELEGDA //