LOCUS       SIU02360.1               214 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 conserved
            protein protein.
ACCESSION   LT708304-3774
PROTEIN_ID  SIU02360.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB3731C"
                     /note="Mb3731c, -, len: 214 aa. Equivalent to Rv3705c,
                     len: 214 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 214 aa overlap). Conserved
                     hypothetical protein, equivalent to Q9CB80|ML2320
                     HYPOTHETICAL PROTEIN from Mycobacterium leprae (215 aa)
                     FASTA scores: opt: 1145, E(): 5.9e-68, (79.45% identity in
                     214 aa overlap). Some similarity to the C-terminal end of
                     Q11053|PKNH_MYCTU|Rv1266c|MT1304|MTCY50.16 PROBABLE
                     SERINE/THREONINE-PROTEIN from Mycobacterium tuberculosis
                     (626 aa), FASTA scores: opt: 175, E(): 0.0005, (24.9%
                     identity in 201 aa overlap); and to the N-terminal end of
                     P23903|E13B_BACCI|GLCA GLUCAN ENDO-1,3-BETA-GLUCOSIDASE A1
                     PRECURSOR from Bacillus circulans (682 aa), FASTA scores:
                     opt: 122, E(): 1.6, (25.6% identity in 164 aa overlap).
                     Protein product from Mb3731c detected using SWATH mass
                     spectrometry. Mb3731c found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="InterPro:IPR026954"
                     /db_xref="InterPro:IPR038232"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y4W8"
BEGIN
        1 MRIAAAVVSI GLAVIAGFAV PVADAHPSEP GVVSYAVLGK GSVGNIVGAP MGWEAVFTRP
       61 FQAFWVELPA CNNWVDIGLP EVYDDPDLAS FNGATTQTSA TDQTHLVKQA VGVFASNDAA
      121 DRAFHRVVDR TVGCSGQTTA IHLDDGTTQV WSFAGGPSTG TDEAWTKQEA GTDRRCFVQT
      181 RLRENVLLQA KVCQSGNAGP AVNVLAGAMQ NTLG
//