LOCUS SIU02360.1 214 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 conserved protein protein. ACCESSION LT708304-3774 PROTEIN_ID SIU02360.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB3731C" /note="Mb3731c, -, len: 214 aa. Equivalent to Rv3705c, len: 214 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 214 aa overlap). Conserved hypothetical protein, equivalent to Q9CB80|ML2320 HYPOTHETICAL PROTEIN from Mycobacterium leprae (215 aa) FASTA scores: opt: 1145, E(): 5.9e-68, (79.45% identity in 214 aa overlap). Some similarity to the C-terminal end of Q11053|PKNH_MYCTU|Rv1266c|MT1304|MTCY50.16 PROBABLE SERINE/THREONINE-PROTEIN from Mycobacterium tuberculosis (626 aa), FASTA scores: opt: 175, E(): 0.0005, (24.9% identity in 201 aa overlap); and to the N-terminal end of P23903|E13B_BACCI|GLCA GLUCAN ENDO-1,3-BETA-GLUCOSIDASE A1 PRECURSOR from Bacillus circulans (682 aa), FASTA scores: opt: 122, E(): 1.6, (25.6% identity in 164 aa overlap). Protein product from Mb3731c detected using SWATH mass spectrometry. Mb3731c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="InterPro:IPR026954" /db_xref="InterPro:IPR038232" /db_xref="UniProtKB/TrEMBL:A0A1R3Y4W8" BEGIN 1 MRIAAAVVSI GLAVIAGFAV PVADAHPSEP GVVSYAVLGK GSVGNIVGAP MGWEAVFTRP 61 FQAFWVELPA CNNWVDIGLP EVYDDPDLAS FNGATTQTSA TDQTHLVKQA VGVFASNDAA 121 DRAFHRVVDR TVGCSGQTTA IHLDDGTTQV WSFAGGPSTG TDEAWTKQEA GTDRRCFVQT 181 RLRENVLLQA KVCQSGNAGP AVNVLAGAMQ NTLG //