LOCUS       SIU02357.1               233 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Amidohydrolase
            EgtC (hercynylcysteine sulfoxide synthase) protein.
ACCESSION   LT708304-3771
PROTEIN_ID  SIU02357.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="egtC"
                     /locus_tag="BQ2027_MB3728C"
                     /note="Mb3728c, -, len: 233 aa. Equivalent to Rv3702c,
                     len: 233 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 233 aa overlap). Conserved
                     hypothetical protein, highly similar to other hypothetical
                     proteins Q9RCZ9|SCM1.45 from Streptomyces coelicolor (271
                     aa), FASTA scores: opt: 383, E(): 2.3e-17, (44.85%
                     identity in 252 aa overlap); and P54004|Y199_SYNY3|SLR0199
                     from Synechocystis sp. strain PCC 6803 (304 aa), FASTA
                     scores: opt: 292, E(): 1.7e-11, (30.05% identity in 263 aa
                     overlap); and similar to others e.g. Q9KMU4|VCA0225 from
                     Vibrio cholerae (254 aa), FASTA scores: opt: 260, E():
                     1.6e-09, (29.8% identity in 245 aa overlap). Equivalent to
                     AAK48172 from Mycobacterium tuberculosis strain CDC1551
                     (194 aa) but longer 39 aa. Protein product from Mb3728c
                     detected using shotgun mass spectrometry and SWATH mass
                     spectrometry. Mb3728c found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:A0A1R3Y4X8"
                     /db_xref="InterPro:IPR017808"
                     /db_xref="InterPro:IPR017932"
                     /db_xref="InterPro:IPR029055"
                     /db_xref="InterPro:IPR032889"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y4X8"
BEGIN
        1 MCRHLGWLGA QVAVSSLVLD PPQGLRVQSY APRRQKHGLM NADGWGVGFF DGAIPRRWRS
       61 PAPLWGDTSF HSVAPALRSH CILAAVRSAT VGMPIEVSAT PPFTDGHWLL AHNGVVDRAV
      121 LPAGPAAESV CDSAILAATI FAHGLDALGD TIVKVGAADP NARLNILAAN GSRLIATTWG
      181 DTLSILRRAD GVVLASEPYD DDSGWGDVPD RHLVEVTQKG VTLTALDRAK GPR
//