LOCUS SIU02351.1 145 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 possible toxin vapc48. contains pin domain. protein. ACCESSION LT708304-3765 PROTEIN_ID SIU02351.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="vapc48" /locus_tag="BQ2027_MB3723C" /note="Mb3723c, -, len: 145 aa. Equivalent to Rv3697c, len: 145 aa, from Mycobacterium tuberculosis strain H37Rv, (99.3% identity in 145 aa overlap). Possible conserved membrane protein, similar to many proteins from Mycobacterium tuberculosis e.g. Q10800|YS72_MYCTU|Rv2872|MT2939|MTCY274.03 (147 aa) FASTA scores: opt: 223, E(): 7.3e-08, (32.6% identity in 141 aa overlap); O53501|Rv2103c|MTV020.03 (144 aa), FASTA scores: opt: 215, E(): 2.4e-07, (31.4% identity in 137 aa overlap); O53812|Rv0749|MTV041.23 (142 aa), FASTA scores: opt: 192, E(): 7.6e-06, (31.25% identity in 144 aa overlap); etc. Mb3723c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:A0A1R3Y4X2" /db_xref="InterPro:IPR002716" /db_xref="InterPro:IPR006226" /db_xref="InterPro:IPR022907" /db_xref="InterPro:IPR029060" /db_xref="UniProtKB/TrEMBL:A0A1R3Y4X2" BEGIN 1 MSETFDVDVL VHATHRASPF HDKAKTLVER FLARPGLVYL LWPVALGYLR VVTHPTLLGA 61 PLAPEVAVEN IEQFTSRPHV RQVGEANGFW PVYRRVADPV KPRGNLVPDA HLVALMRHHG 121 IATIWSHDRD FRKFEGIRIR DPFSG //