LOCUS       SIU02351.1               145 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 possible
            toxin vapc48. contains pin domain. protein.
ACCESSION   LT708304-3765
PROTEIN_ID  SIU02351.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="vapc48"
                     /locus_tag="BQ2027_MB3723C"
                     /note="Mb3723c, -, len: 145 aa. Equivalent to Rv3697c,
                     len: 145 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.3% identity in 145 aa overlap). Possible conserved
                     membrane protein, similar to many proteins from
                     Mycobacterium tuberculosis e.g.
                     Q10800|YS72_MYCTU|Rv2872|MT2939|MTCY274.03 (147 aa) FASTA
                     scores: opt: 223, E(): 7.3e-08, (32.6% identity in 141 aa
                     overlap); O53501|Rv2103c|MTV020.03 (144 aa), FASTA scores:
                     opt: 215, E(): 2.4e-07, (31.4% identity in 137 aa
                     overlap); O53812|Rv0749|MTV041.23 (142 aa), FASTA scores:
                     opt: 192, E(): 7.6e-06, (31.25% identity in 144 aa
                     overlap); etc. Mb3723c found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:A0A1R3Y4X2"
                     /db_xref="InterPro:IPR002716"
                     /db_xref="InterPro:IPR006226"
                     /db_xref="InterPro:IPR022907"
                     /db_xref="InterPro:IPR029060"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y4X2"
BEGIN
        1 MSETFDVDVL VHATHRASPF HDKAKTLVER FLARPGLVYL LWPVALGYLR VVTHPTLLGA
       61 PLAPEVAVEN IEQFTSRPHV RQVGEANGFW PVYRRVADPV KPRGNLVPDA HLVALMRHHG
      121 IATIWSHDRD FRKFEGIRIR DPFSG
//