LOCUS       SIU02342.1               451 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            CONSERVED TRANSMEMBRANE PROTEIN protein.
ACCESSION   LT708304-3756
PROTEIN_ID  SIU02342.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB3714"
                     /note="Mb3714, -, len: 451 aa. Equivalent to Rv3689, len:
                     451 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.8% identity in 451 aa overlap). Probable conserved
                     transmembrane protein, with Proline rich N-terminus,
                     similar to Q9KYW6|SCE33.17 PUTATIVE INTEGRAL MEMBRANE
                     PROTEIN from Streptomyces coelicolor (462 aa) FASTA
                     scores: opt: 730, E(): 2.7e-21, (38.1% identity in 412 aa
                     overlap). Mb3714 found to be expressed during exponential
                     growth in Sauton's minimal media by RNA-sequencing (TPM >
                     20)."
                     /db_xref="GOA:A0A1R3Y4X6"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y4X6"
BEGIN
        1 MHKRYAPQRP KPDTETYIEK CTDRRQDGGH DERRQLLRPV SMLPPGYPVE PPPVAPGYAP
       61 AGYPPYPATP PGYGPPGYGA PPSYGPPPGY GPPLGYPAAP PGCGPPPGYG PPLGYGPPLA
      121 PGAVKPGIIP LRPLTLSDIF NGAVGYIRAN PKATLGLTAM VVVTLQIISL VALFGPMTAF
      181 GDIVTGEPDE LTGAVVGGWS ASFGASLLVS WLAGVLLSGM LTVIVGRAVF GSPITVGEAW
      241 AKVRGRLLAL FGLALLEAAG VVAVLGLAVV ILSGVAAAAN EAAAALLGFP LLLVVGVSLA
      301 YLYVVLLFAP VLIVLERLPI VEAITRSFAL VRHGFWRVLG IRLLTVLVVG VVGNAIAAPF
      361 MIVGEIVTAV TASDGSVTMR LVGATLSAIG VTIGQIVTAP FSAGVVVLLY TDRRIRAEAF
      421 DLVLQTGLEA GPAGGPAPVE STDNLWLTRP F
//