LOCUS SIU02321.1 172 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE CONSERVED TRANSMEMBRANE PROTEIN protein. ACCESSION LT708304-3735 PROTEIN_ID SIU02321.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB3693" /note="Mb3693, -, len: 172 aa. Equivalent to Rv3669, len: 172 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 172 aa overlap). Probable conserved transmembrane protein, equivalent to Q9CB97|ML2296 PUTATIVE MEMBRANE PROTEIN from Mycobacterium leprae (181 aa), FASTA scores: opt: 863, E(): 1.4e-47, (77.35% identity in 181 aa overlap). Also similar to two PUTATIVE INTEGRAL MEMBRANE TRANSPORT PROTEINS from Streptomyces coelicolor; Q9X930|SCH5.28 (162 aa) FASTA scores: opt: 265, E(): 6.3e-10, (37.4% identity in 155 aa overlap); and Q9X9W1|SCI7.29c (165 aa), FASTA scores: opt: 194, E(): 1.9e-05, (30.6% identity in 134 aa overlap). Contains two hydrophobic stretches in centre. Protein product from Mb3693 detected using shotgun mass spectrometry. Mb3693 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing (TPM > 20)." /db_xref="GOA:A0A1R3Y4S2" /db_xref="InterPro:IPR009937" /db_xref="UniProtKB/TrEMBL:A0A1R3Y4S2" BEGIN 1 MSKIDRKNGV PSTLTTIPLA DPHAGPAEPS IGDLIKDATT QMSTLVRAEV ELARAEITRD 61 VKKGLTGSVF FISSLVVGFY STFFFFFFVA ELLDTWIWRW VAFLLVFAIM VVVTAVLALL 121 GFLKVRRIRG PRQTIASVKE TRTALTPGHD KTPVTPKPVT SDRATPVDPS GW //