LOCUS       SIU02321.1               172 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            CONSERVED TRANSMEMBRANE PROTEIN protein.
ACCESSION   LT708304-3735
PROTEIN_ID  SIU02321.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB3693"
                     /note="Mb3693, -, len: 172 aa. Equivalent to Rv3669, len:
                     172 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 172 aa overlap). Probable conserved
                     transmembrane protein, equivalent to Q9CB97|ML2296
                     PUTATIVE MEMBRANE PROTEIN from Mycobacterium leprae (181
                     aa), FASTA scores: opt: 863, E(): 1.4e-47, (77.35%
                     identity in 181 aa overlap). Also similar to two PUTATIVE
                     INTEGRAL MEMBRANE TRANSPORT PROTEINS from Streptomyces
                     coelicolor; Q9X930|SCH5.28 (162 aa) FASTA scores: opt:
                     265, E(): 6.3e-10, (37.4% identity in 155 aa overlap); and
                     Q9X9W1|SCI7.29c (165 aa), FASTA scores: opt: 194, E():
                     1.9e-05, (30.6% identity in 134 aa overlap). Contains two
                     hydrophobic stretches in centre. Protein product from
                     Mb3693 detected using shotgun mass spectrometry. Mb3693
                     found to be expressed during exponential growth in
                     Sauton's minimal media by RNA-sequencing (TPM > 20)."
                     /db_xref="GOA:A0A1R3Y4S2"
                     /db_xref="InterPro:IPR009937"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y4S2"
BEGIN
        1 MSKIDRKNGV PSTLTTIPLA DPHAGPAEPS IGDLIKDATT QMSTLVRAEV ELARAEITRD
       61 VKKGLTGSVF FISSLVVGFY STFFFFFFVA ELLDTWIWRW VAFLLVFAIM VVVTAVLALL
      121 GFLKVRRIRG PRQTIASVKE TRTALTPGHD KTPVTPKPVT SDRATPVDPS GW
//